| 1. |
-
- 2019
-
Tidskriftsartikel (refereegranskat)
|
|
| 2. |
- Kattge, Jens, et al.
(författare)
-
TRY plant trait database - enhanced coverage and open access
- 2020
-
Ingår i: Global Change Biology. - : Wiley-Blackwell. - 1354-1013 .- 1365-2486. ; 26:1, s. 119-188
-
Tidskriftsartikel (refereegranskat)abstract
- Plant traits-the morphological, anatomical, physiological, biochemical and phenological characteristics of plants-determine how plants respond to environmental factors, affect other trophic levels, and influence ecosystem properties and their benefits and detriments to people. Plant trait data thus represent the basis for a vast area of research spanning from evolutionary biology, community and functional ecology, to biodiversity conservation, ecosystem and landscape management, restoration, biogeography and earth system modelling. Since its foundation in 2007, the TRY database of plant traits has grown continuously. It now provides unprecedented data coverage under an open access data policy and is the main plant trait database used by the research community worldwide. Increasingly, the TRY database also supports new frontiers of trait-based plant research, including the identification of data gaps and the subsequent mobilization or measurement of new data. To support this development, in this article we evaluate the extent of the trait data compiled in TRY and analyse emerging patterns of data coverage and representativeness. Best species coverage is achieved for categorical traits-almost complete coverage for 'plant growth form'. However, most traits relevant for ecology and vegetation modelling are characterized by continuous intraspecific variation and trait-environmental relationships. These traits have to be measured on individual plants in their respective environment. Despite unprecedented data coverage, we observe a humbling lack of completeness and representativeness of these continuous traits in many aspects. We, therefore, conclude that reducing data gaps and biases in the TRY database remains a key challenge and requires a coordinated approach to data mobilization and trait measurements. This can only be achieved in collaboration with other initiatives.
|
|
| 3. |
- Leebens-Mack, James H., et al.
(författare)
-
One thousand plant transcriptomes and the phylogenomics of green plants
- 2019
-
Ingår i: Nature. - : Nature Publishing Group. - 0028-0836 .- 1476-4687. ; 574:7780, s. 679-
-
Tidskriftsartikel (refereegranskat)abstract
- Green plants (Viridiplantae) include around 450,000-500,000 species(1,2) of great diversity and have important roles in terrestrial and aquatic ecosystems. Here, as part of the One Thousand Plant Transcriptomes Initiative, we sequenced the vegetative transcriptomes of 1,124 species that span the diversity of plants in a broad sense (Archaeplastida), including green plants (Viridiplantae), glaucophytes (Glaucophyta) and red algae (Rhodophyta). Our analysis provides a robust phylogenomic framework for examining the evolution of green plants. Most inferred species relationships are well supported across multiple species tree and supermatrix analyses, but discordance among plastid and nuclear gene trees at a few important nodes highlights the complexity of plant genome evolution, including polyploidy, periods of rapid speciation, and extinction. Incomplete sorting of ancestral variation, polyploidization and massive expansions of gene families punctuate the evolutionary history of green plants. Notably, we find that large expansions of gene families preceded the origins of green plants, land plants and vascular plants, whereas whole-genome duplications are inferred to have occurred repeatedly throughout the evolution of flowering plants and ferns. The increasing availability of high-quality plant genome sequences and advances in functional genomics are enabling research on genome evolution across the green tree of life.
|
|
| 4. |
- Lundgren, Markus, et al.
(författare)
-
Analgesic antipyretic use among young children in the TEDDY study : No association with islet autoimmunity
- 2017
-
Ingår i: BMC Pediatrics. - : Springer Science and Business Media LLC. - 1471-2431. ; 17:1
-
Tidskriftsartikel (refereegranskat)abstract
- Background: The use of analgesic antipyretics (ANAP) in children have long been a matter of controversy. Data on their practical use on an individual level has, however, been scarce. There are indications of possible effects on glucose homeostasis and immune function related to the use of ANAP. The aim of this study was to analyze patterns of analgesic antipyretic use across the clinical centers of The Environmental Determinants of Diabetes in the Young (TEDDY) prospective cohort study and test if ANAP use was a risk factor for islet autoimmunity. Methods: Data were collected for 8542 children in the first 2.5 years of life. Incidence was analyzed using logistic regression with country and first child status as independent variables. Holm's procedure was used to adjust for multiplicity of intercountry comparisons. Time to autoantibody seroconversion was analyzed using a Cox proportional hazards model with cumulative analgesic use as primary time dependent covariate of interest. For each categorization, a generalized estimating equation (GEE) approach was used. Results: Higher prevalence of ANAP use was found in the U.S. (95.7%) and Sweden (94.8%) compared to Finland (78.1%) and Germany (80.2%). First-born children were more commonly given acetaminophen (OR 1.26; 95% CI 1.07, 1.49; p = 0.007) but less commonly Non-Steroidal Anti-inflammatory Drugs (NSAID) (OR 0.86; 95% CI 0.78, 0.95; p = 0.002). Acetaminophen and NSAID use in the absence of fever and infection was more prevalent in the U.S. (40.4%; 26.3% of doses) compared to Sweden, Finland and Germany (p < 0.001). Acetaminophen or NSAID use before age 2.5 years did not predict development of islet autoimmunity by age 6 years (HR 1.02, 95% CI 0.99-1.09; p = 0.27). In a sub-analysis, acetaminophen use in children with fever weakly predicted development of islet autoimmunity by age 3 years (HR 1.05; 95% CI 1.01-1.09; p = 0.024). Conclusions: ANAP use in young children is not a risk factor for seroconversion by age 6 years. Use of ANAP is widespread in young children, and significantly higher in the U.S. compared to other study sites, where use is common also in absence of fever and infection.
|
|
| 5. |
|
|
| 6. |
|
|
| 7. |
-
Architecture in effect : vol 1. Rethinking the social in architecture: making effects
- 2018
-
Samlingsverk (redaktörskap) (refereegranskat)abstract
- Architecture in Effect presents research on the co-constitution of architecture and the social by addressing concrete problems and forwarding explorative theories and methodologies. The book compromises a wide-ranging collection of essays emerging from a multi-year research collective that has brought together partners from Sweden, the Nordic countries, the United Kingdom, Europe and the United States.The socially oriented perspective of Volume #1, Rethinking the Social, is complemented by discussions of architectural and transdisciplinary theories and methodologies in Volume #2, After Effects. Together these twin volumes reflect on topics such as the utopian idea of a welfare state, the role of intersubjective and non-human points of view, and the impact of historical and current images on the making of realities. The task of these books is to present a wide range of research topics that combine historical, material, and critical research approaches that respond to our current crises and challenges. Ultimately, this enables new modes of knowledge production within architecture to be advanced in its relation to societal transformation.
|
|
| 8. |
-
Architecture in Effect Vol #1(2) : Rethinking the Social in Architecture – Making Effects.
- 2019
-
Samlingsverk (redaktörskap) (refereegranskat)abstract
- Architecture in Effect is a substantial double volume that compiles 50 essays emerging from the architectural research environment of Sweden and drawing on a complex matrix of international collaborations. A central premise of the collected research is to question the relationship between the built environment and societal norms and to interrogate architecture’s role in these co-constitutive processes. The Architecture in Effect project is concerned with how contemporary political and environmental conditions place specific demands on society and on the everyday life of individuals. Architectural researchers have the capacity to both initiate and criticize architectural production and culture amidst existing and emerging societies. Architecture in Effect is published by Actar Barcelona New York (2019). Rethinking the Social in Architecture: Making Effects Volume 01 Edited by Sten Gromark, Jennifer Mack, Roemer van Toorn That architecture serves as the setting for social actions, activities, and content is not a new idea. That the architectural project can precipitate crucial social change, even transgression, is a far more modern and disputed claim. Spatial design in society has recently shifted away from universal solutions toward satisfying specific market orientated interests. The time is now to reclaim architecture’s role in promoting political, economic, ecological, and cultural transformations. The radicality of architecture is renewed in the exploration of novel and unforeseen possibilities: making effects.
|
|
| 9. |
- Boric, Bojan
(författare)
-
The Ghost Boulevard
- 2020
-
Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- In 1947, Soviet architect Alexey Shchusev developed a large-scale urban renewal project for the post-war city of Chisinau, the then-capital of the SSR of Moldova. Part of the master plan was the construction of Boulevard D. Cantemir, which would cut through the city’s historic fabric. Only two sections of the boulevard were built before the project was abandoned. During the period of radical institutional political and economic shift towards a market economy in the early 1990s, initiatives to build the boulevard re-emerged through red lines, zoning documents, and planning regulations. The lack of political consensus caused planning paralyses over the city, creating a legal void where different actors competed to appropriate spaces. The power of the red lines has prompted various kinds of materializations of the boulevard. The real battle takes place in the sphere of the imaginary, and memory management is one of the main planning tools. Exploring the trajectory of the “Ghost Boulevard,” I reveal conflicting political and economic agendas and the many forces that constitute complex processes of planning today.
|
|
| 10. |
- Botvinik-Nezer, Rotem, et al.
(författare)
-
Variability in the analysis of a single neuroimaging dataset by many teams
- 2020
-
Ingår i: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 582, s. 84-88
-
Tidskriftsartikel (refereegranskat)abstract
- Data analysis workflows in many scientific domains have become increasingly complex and flexible. Here we assess the effect of this flexibility on the results of functional magnetic resonance imaging by asking 70 independent teams to analyse the same dataset, testing the same 9 ex-ante hypotheses(1). The flexibility of analytical approaches is exemplified by the fact that no two teams chose identical workflows to analyse the data. This flexibility resulted in sizeable variation in the results of hypothesis tests, even for teams whose statistical maps were highly correlated at intermediate stages of the analysis pipeline. Variation in reported results was related to several aspects of analysis methodology. Notably, a meta-analytical approach that aggregated information across teams yielded a significant consensus in activated regions. Furthermore, prediction markets of researchers in the field revealed an overestimation of the likelihood of significant findings, even by researchers with direct knowledge of the dataset(2-5). Our findings show that analytical flexibility can have substantial effects on scientific conclusions, and identify factors that may be related to variability in the analysis of functional magnetic resonance imaging. The results emphasize the importance of validating and sharing complex analysis workflows, and demonstrate the need for performing and reporting multiple analyses of the same data. Potential approaches that could be used to mitigate issues related to analytical variability are discussed. The results obtained by seventy different teams analysing the same functional magnetic resonance imaging dataset show substantial variation, highlighting the influence of analytical choices and the importance of sharing workflows publicly and performing multiple analyses.
|
|
