SwePub
Sök i LIBRIS databas

  Utökad sökning

WFRF:(Mahteme Haile)
 

Sökning: WFRF:(Mahteme Haile) > (2010-2014) > Granath F. > Incidence, prevalen...

Incidence, prevalence and risk factors for peritoneal carcinomatosis from colorectal cancer

Segelman, J. (författare)
Karolinska Institutet
Granath, F. (författare)
Karolinska Institutet
Holm, T. (författare)
Karolinska Institutet
visa fler...
Machado, M. (författare)
Mahteme, Haile (författare)
Uppsala universitet,Kolorektalkirurgi
Martling, A. (författare)
Karolinska Institutet
visa färre...
 (creator_code:org_t)
2012-01-27
2012
Engelska.
Ingår i: British Journal of Surgery. - : Oxford University Press (OUP). - 0007-1323 .- 1365-2168. ; 99:5, s. 699-705
  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
Stäng  
  • Background: This was a population-based cohort study to determine the incidence, prevalence and risk factors for peritoneal carcinomatosis (PC) from colorectal cancer. Methods: Prospectively collected data were obtained from the Regional Quality Registry. The Cox proportional hazards regression model was used for multivariable analysis of clinicopathological factors to determine independent predictors of PC. Results: All 11 124 patients with colorectal cancer in Stockholm County during 1995-2007 were included and followed until 2010. In total, 924 patients (8.3 per cent) had synchronous or metachronous PC. PC was the first and only localization of metastases in 535 patients (4.8 per cent). The prevalence of synchronous PC was 4.3 per cent (477 of 11 124). The cumulative incidence of metachronous PC was 4.2 per cent (447 of 10 646). Independent predictors for metachronous PC were colonic cancer (hazard ratio (HR) 1.77, 95 per cent confidence interval 1.31 to 2.39; P = 0.002 for right-sided colonic cancer), advanced tumour (T) status (HR 9.98, 3.10 to 32.11; P < 0.001 for T4), advanced node (N) status (HR 7.41, 4.78 to 11.51; P < 0.001 for N2 with fewer than 12 lymph nodes examined), emergency surgery (HR 2.11, 1.66 to 2.69; P < 0.001) and non-radical resection of the primary tumour (HR 2.75, 2.10 to 3.61; P < 0.001 for R2 resection). Patients aged > 70 years had a decreased risk of metachronous PC (HR 0.69, 0.55 to 0.87; P = 0.003). Conclusion: PC is common in patients with colorectal cancer and is associated with identifiable risk factors.

Publikations- och innehållstyp

ref (ämneskategori)
art (ämneskategori)

Hitta via bibliotek

Till lärosätets databas

Sök utanför SwePub

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy