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Träfflista för sökning "WFRF:(Maibach Howard I.) ;pers:(Menné Torkil)"

Search: WFRF:(Maibach Howard I.) > Menné Torkil

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1.
  • Schalock, Peter C, et al. (author)
  • Hypersensitivity reactions to metallic implants-diagnostic algorithm and suggested patch test series for clinical use.
  • 2012
  • In: Contact Dermatitis. - : Wiley. - 0105-1873 .- 1600-0536. ; 66:1, s. 4-19
  • Journal article (peer-reviewed)abstract
    • Cutaneous and systemic hypersensitivity reactions to implanted metals are challenging to evaluate and treat. Although they are uncommon, they do exist, and require appropriate and complete evaluation. This review summarizes the evidence regarding evaluation tools, especially patch and lymphocyte transformation tests, for hypersensitivity reactions to implanted metal devices. Patch test evaluation is the gold standard for metal hypersensitivity, although the results may be subjective. Regarding pre-implant testing, those patients with a reported history of metal dermatitis should be evaluated by patch testing. Those without a history of dermatitis should not be tested unless considerable concern exists. Regarding post-implant testing, a subset of patients with metal hypersensitivity may develop cutaneous or systemic reactions to implanted metals following implant. For symptomatic patients, a diagnostic algorithm to guide the selection of screening allergen series for patch testing is provided. At a minimum, an extended baseline screening series and metal screening is necessary. Static and dynamic orthopaedic implants, intravascular stent devices, implanted defibrillators and dental and gynaecological devices are considered. Basic management suggestions are provided. Our goal is to provide a comprehensive reference for use by those evaluating suspected cutaneous and systemic metal hypersensitivity reactions.
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2.
  • Thyssen, Jacob P., et al. (author)
  • Sensitivity and specificity of the nickel spot (dimethylglyoxime) test
  • 2010
  • In: Contact Dermatitis. - 0105-1873 .- 1600-0536. ; 62:5, s. 279-288
  • Journal article (peer-reviewed)abstract
    • Objectives: To evaluate the sensitivity and specificity of the DMG test. Methods: DMG spot testing, chemical analysis according to the EN 1811 reference method, and X-ray fluorescence spectroscopy (XRF) were performed concomitantly on 96 metallic components from earrings recently purchased in San Francisco. Results: The sensitivity of the DMG test was 59.3% and the specificity was 97.5% based on DMG-test results and nickel release concentrations determined by the EN 1811 reference method. Conclusions: The DMG test has a high specificity but a modest sensitivity. It may serve well for screening purposes. Past exposure studies may have underestimated nickel release from consumer items.
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  • Result 1-2 of 2
Type of publication
journal article (2)
Type of content
peer-reviewed (2)
Author/Editor
Lidén, Carola (2)
Maibach, Howard I. (2)
Johansen, Jeanne D. (2)
Thyssen, Jacob P. (2)
Menné, Torkil (2)Undo refine
Bruze, Magnus (1)
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Lundgren, Lennart (1)
Skare, Lizbet (1)
Taylor, James S (1)
Schalock, Peter C (1)
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University
Stockholm University (1)
Lund University (1)
Karolinska Institutet  (1)Undo refine
Language
English (2)
Research subject (UKÄ/SCB)
Medical and Health Sciences (1)

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