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Numrering	Referens	Omslagsbild	Hitta
1.	Bruze, Magnus, et al. (författare) Patch testing with methylchloroisothiazolinone/methylisothiazolinone 200 ppm aq. detects significantly more contact allergy than 100 ppm. A multicentre study within the European Environmental and Contact Dermatitis Research Group. 2014 Ingår i: Contact Dermatitis. - : Wiley. - 0105-1873. ; 71:1, s. 31-34 Tidskriftsartikel (refereegranskat)abstract Methylchloroisothiazolinone (MCI) and methylisothiazolinone (MI) are the active ingredients in commonly used preservative systems (e.g. Kathon CG(®) ). MCI/MI is present in the European baseline patch test series at 100 ppm aq. Since 1986, 200 ppm (dose 0.006 mg/cm(2) ) has been used in Sweden without causing skin irritation. Centres in Spain, the United Kingdom and Ireland have also used 200 ppm in their baseline series.
2.	Isaksson, Marléne, et al. (författare) Multicentre patch testing with methylisothiazolinone by the European Environmental and Contact Dermatitis Research Group. 2014 Ingår i: Contact Dermatitis. - : Wiley. - 0105-1873. ; 70:5, s. 78-317 Tidskriftsartikel (refereegranskat)
3.	Pontén, Ann, et al. (författare) Patch testing with 2.0% (0.60 mg/cm(2) ) formaldehyde instead of 1.0% (0.30 mg/cm(2) ) detects significantly more contact allergy. 2013 Ingår i: Contact Dermatitis. - : Wiley. - 0105-1873. ; 68:1, s. 50-53 Tidskriftsartikel (refereegranskat)abstract Background.The currently used patch test concentration for formaldehyde is 1.0% (wt/vol) in water. However, clinical experience and previous studies suggest that 1.0% might be insufficient for detecting an optimized number of clinically relevant cases of contact allergy to formaldehyde. Objectives.To validate earlier patch test results for comparison of 1% (wt/vol) and 2% (wt/vol) formaldehyde in water, and to investigate co-reactivity with quaternium-15. Materials and methods.In 12 dermatology clinics, 3591 patients were routinely patch tested simultaneously with 2.0% (wt/vol) (0.60 mg/cm(2) ) and 1.0% (wt/vol) (0.30 mg/cm(2) ) formaldehyde. Micropipettes were used for delivering the exact dosage of the allergen. Results.Significantly more patients reacted to 2.0% formaldehyde than to 1.0% (3.4% versus 1.8%, p < 0.001). Overall, there were no sex differences between those reacting positively to 2.0% and 1.0%. Of 25 quaternium-15-positive patients, 4 (0.1%) reacted positively without reacting to formaldehyde. Conclusion.On the basis of the results of this multicentre study, as well as of previous studies, it can be suggested that 2.0% (wt/vol) in water formaldehyde should be used in routine patch testing in the baseline series.

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Typ av publikation: tidskriftsartikel (3)

Typ av innehåll: refereegranskat (3)

Författare/redaktör: Bruze, Magnus (3); Goossens, An (3); Goncalo, Margarida (3); Le Coz, Christophe J ... (3); Rustemeyer, Thom... (3)Ta bort avgränsningen; White, Ian R. (3); visa fler...; Andersen, Klaus E (3); Maibach, Howard I. (3); Isaksson, Marléne (2); Gruvberger, Birgitta (2); Johansen, Jeanne D. (2); Agner, Tove (1); Johansen, Jeanne Duu ... (1); Pontén, Ann (1); Aalto-Korte, Kristii ... (1); Giménez-Arnau, Ana M ... (1); visa färre...

Lärosäte: Lunds universitet (3)

Språk: Engelska (3)

Forskningsämne (UKÄ/SCB): Medicin och hälsovetenskap (3)

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