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Allergic contact de...
Allergic contact dermatitis caused by isobornyl acrylate in Freestyle® Libre, a newly introduced glucose sensor
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- Herman, Anne (författare)
- Saint-Luc University Hospital
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- Aerts, Olivier (författare)
- University of Antwerp,Antwerp University Hospital
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- Baeck, Marie (författare)
- Saint-Luc University Hospital
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- Bruze, Magnus (författare)
- Lund University,Lunds universitet,Yrkes- och miljödermatologi,Forskargrupper vid Lunds universitet,Occupational and Environmental Dermatology,Lund University Research Groups,Skåne University Hospital
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- De Block, Christophe (författare)
- Antwerp University Hospital,University of Antwerp
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- Goossens, An (författare)
- Catholic University of Leuven,University Hospitals Leuven
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- Hamnerius, Nils (författare)
- Lund University,Lunds universitet,Yrkes- och miljödermatologi,Forskargrupper vid Lunds universitet,Occupational and Environmental Dermatology,Lund University Research Groups,Skåne University Hospital
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- Huygens, Sara (författare)
- University Hospitals Leuven,Catholic University of Leuven
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- Maiter, Dominique (författare)
- Saint-Luc University Hospital
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- Tennstedt, Dominique (författare)
- Saint-Luc University Hospital
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- Vandeleene, Bernard (författare)
- Saint-Luc University Hospital
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- Mowitz, Martin (författare)
- Lund University,Lunds universitet,Yrkes- och miljödermatologi,Forskargrupper vid Lunds universitet,Occupational and Environmental Dermatology,Lund University Research Groups,Skåne University Hospital
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(creator_code:org_t)
- 2017-08-14
- 2017
- Engelska 7 s.
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Ingår i: Contact Dermatitis. - : Wiley. - 0105-1873. ; 77:6, s. 367-373
- Relaterad länk:
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http://dx.doi.org/10...
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https://www.onlineli...
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https://lup.lub.lu.s...
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https://doi.org/10.1...
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Abstract
Ämnesord
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- Background: Glucose sensors, such as FreeStyle® Libre, are innovative medical devices developed for diabetes patients as a replacement for classic glucose meters, ensuring continuous glucose monitoring without the disadvantage of regular skin finger pricks. Objectives: To report several cases of allergic contact dermatitis caused by FreeStyle® Libre, and to report on isobornyl acrylate as a culprit allergen. Patients and Methods: Fifteen patients presented with allergic contact dermatitis caused by FreeStyle® Libre. All but 1 were patch tested with a baseline series, and with pieces and/or ultrasonic bath extracts of (the adhesive part of) the glucose sensor. Isobornyl acrylate was patch tested, in various concentrations and vehicles, in 13 patients. Gas chromatography–mass spectrometry (GC-MS) of the sensors was performed. Results: All patients reacted to the adhesive part of the sensor, and 12 patients were shown to be sensitized to isobornyl acrylate. Simultaneous reactions to other allergens were rarely observed. GC-MS showed the presence of isobornyl acrylate in the sensors. Conclusions: Cases of allergic contact dermatitis caused by FreeStyle® Libre are increasingly being observed, and isobornyl acrylate is a relevant culprit allergen. Cross-reactivity to other acrylates was infrequently observed, but other, hitherto unidentified, contact allergens may still be present in the device.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Dermatologi och venereologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Dermatology and Venereal Diseases (hsv//eng)
Nyckelord
- acrylates
- adhesive
- allergic contact dermatitis
- CAS no. 5888-33-5
- diabetes mellitus
- FreeStyle® Libre
- gas chromatography
- glucose sensor
- isobornyl acrylate
- mass spectrometry
- medical device
- sesquiterpene lactone mix
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- art (ämneskategori)
- ref (ämneskategori)
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Herman, Anne
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Aerts, Olivier
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Baeck, Marie
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Bruze, Magnus
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De Block, Christ ...
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Goossens, An
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visa fler...
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Hamnerius, Nils
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Huygens, Sara
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Maiter, Dominiqu ...
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Tennstedt, Domin ...
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Vandeleene, Bern ...
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Mowitz, Martin
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