SwePub
Tyck till om SwePub Sök här!
Sök i LIBRIS databas

  Extended search

WFRF:(Mates Dana)
 

Search: WFRF:(Mates Dana) > (2010-2014) > Tiemeier Henning > Genome-wide meta-an...

  • 1 of 1
  • Previous record
  • Next record
  •    To hitlist

Genome-wide meta-analyses identify multiple loci associated with smoking behavior

Furberg, Helena (author)
Kim, YunJung (author)
Dackor, Jennifer (author)
show more...
Boerwinkle, Eric (author)
Franceschini, Nora (author)
Ardissino, Diego (author)
Bernardinelli, Luisa (author)
Mannucci, Pier M. (author)
Mauri, Francesco (author)
Merlini, Piera A. (author)
Absher, Devin (author)
Assimes, Themistocles L. (author)
Fortmann, Stephen P. (author)
Iribarren, Carlos (author)
Knowles, Joshua W. (author)
Quertermous, Thomas (author)
Ferrucci, Luigi (author)
Tanaka, Toshiko (author)
Bis, Joshua C. (author)
Furberg, Curt D. (author)
Haritunians, Talin (author)
McKnight, Barbara (author)
Psaty, Bruce M. (author)
Taylor, Kent D. (author)
Thacker, Evan L. (author)
Almgren, Peter (author)
Lund University,Lunds universitet,Genomik, diabetes och endokrinologi,Forskargrupper vid Lunds universitet,Genomics, Diabetes and Endocrinology,Lund University Research Groups
Groop, Leif (author)
Lund University,Lunds universitet,Genomik, diabetes och endokrinologi,Forskargrupper vid Lunds universitet,Genomics, Diabetes and Endocrinology,Lund University Research Groups
Ladenvall, Claes (author)
Lund University,Lunds universitet,Genomik, diabetes och endokrinologi,Forskargrupper vid Lunds universitet,Genomics, Diabetes and Endocrinology,Lund University Research Groups
Boehnke, Michael (author)
Jackson, Anne U. (author)
Mohlke, Karen L. (author)
Stringham, Heather M. (author)
Tuomilehto, Jaakko (author)
Benjamin, Emelia J. (author)
Hwang, Shih-Jen (author)
Levy, Daniel (author)
Preis, Sarah Rosner (author)
Vasan, Ramachandran S. (author)
Duan, Jubao (author)
Gejman, Pablo V. (author)
Levinson, Douglas F. (author)
Sanders, Alan R. (author)
Shi, Jianxin (author)
Lips, Esther H. (author)
Mckay, James D. (author)
Agudo, Antonio (author)
Barzan, Luigi (author)
Bencko, Vladimir (author)
Benhamou, Simone (author)
Castellsague, Xavier (author)
Canova, Cristina (author)
Conway, David I. (author)
Fabianova, Eleonora (author)
Foretova, Lenka (author)
Janout, Vladimir (author)
Healy, Claire M. (author)
Holcatova, Ivana (author)
Kjaerheim, Kristina (author)
Lagiou, Pagona (author)
Lissowska, Jolanta (author)
Lowry, Ray (author)
Macfarlane, Tatiana V. (author)
Mates, Dana (author)
Richiardi, Lorenzo (author)
Rudnai, Peter (author)
Szeszenia-Dabrowska, Neonilia (author)
Zaridze, David (author)
Znaor, Ariana (author)
Lathrop, Mark (author)
Brennan, Paul (author)
Bandinelli, Stefania (author)
Frayling, Timothy M. (author)
Guralnik, Jack M. (author)
Milaneschi, Yuri (author)
Perry, John R. B. (author)
Altshuler, David (author)
Elosua, Roberto (author)
Kathiresan, Sek (author)
Lucas, Gavin (author)
Melander, Olle (author)
Lund University,Lunds universitet,Kardiovaskulär forskning - hypertoni,Forskargrupper vid Lunds universitet,Cardiovascular Research - Hypertension,Lund University Research Groups
O'Donnell, Christopher J. (author)
Salomaa, Veikko (author)
Schwartz, Stephen M. (author)
Voight, Benjamin F. (author)
Penninx, Brenda W. (author)
Smit, Johannes H. (author)
Vogelzangs, Nicole (author)
Boomsma, Dorret I. (author)
de Geus, Eco J. C. (author)
Vink, Jacqueline M. (author)
Willemsen, Gonneke (author)
Chanock, Stephen J. (author)
Gu, Fangyi (author)
Hankinson, Susan E. (author)
Hunter, David J. (author)
Hofman, Albert (author)
Tiemeier, Henning (author)
Uitterlinden, Andre G. (author)
van Duijn, Cornelia M. (author)
Walter, Stefan (author)
Chasman, Daniel I. (author)
Everett, Brendan M. (author)
Pare, Guillaume (author)
Ridker, Paul M. (author)
Li, Ming D. (author)
Maes, Hermine H. (author)
Audrain-McGovern, Janet (author)
Posthuma, Danielle (author)
Thornton, Laura M. (author)
Lerman, Caryn (author)
Kaprio, Jaakko (author)
Rose, Jed E. (author)
Ioannidis, John P. A. (author)
Kraft, Peter (author)
Lin, Dan-Yu (author)
Sullivan, Patrick F. (author)
show less...
 (creator_code:org_t)
2010-04-25
2010
English.
In: Nature Genetics. - : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 42:5, s. 134-441
  • Journal article (peer-reviewed)
Abstract Subject headings
Close  
  • Consistent but indirect evidence has implicated genetic factors in smoking behavior1,2. We report meta-analyses of several smoking phenotypes within cohorts of the Tobacco and Genetics Consortium (n = 74,053). We also partnered with the European Network of Genetic and Genomic Epidemiology (ENGAGE) and Oxford-GlaxoSmithKline (Ox-GSK) consortia to follow up the 15 most significant regions (n > 140,000). We identified three loci associated with number of cigarettes smoked per day. The strongest association was a synonymous 15q25 SNP in the nicotinic receptor gene CHRNA3 (rs1051730[A], b = 1.03, standard error (s.e.) = 0.053, beta = 2.8 x 10(-73)). Two 10q25 SNPs (rs1329650[G], b = 0.367, s. e. = 0.059, beta = 5.7 x 10(-10); and rs1028936[A], b = 0.446, s. e. = 0.074, beta = 1.3 x 10(-9)) and one 9q13 SNP in EGLN2 (rs3733829[G], b = 0.333, s. e. = 0.058, P = 1.0 x 10(-8)) also exceeded genome-wide significance for cigarettes per day. For smoking initiation, eight SNPs exceeded genome-wide significance, with the strongest association at a nonsynonymous SNP in BDNF on chromosome 11 (rs6265[C], odds ratio (OR) = 1.06, 95% confidence interval (Cl) 1.04-1.08, P = 1.8 x 10(-8)). One SNP located near DBH on chromosome 9 (rs3025343[G], OR = 1.12, 95% Cl 1.08-1.18, P = 3.6 x 10(-8)) was significantly associated with smoking cessation.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Kardiologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Endokrinologi och diabetes (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Endocrinology and Diabetes (hsv//eng)

Publication and Content Type

art (subject category)
ref (subject category)

Find in a library

To the university's database

  • 1 of 1
  • Previous record
  • Next record
  •    To hitlist

Find more in SwePub

By the author/editor
Furberg, Helena
Kim, YunJung
Dackor, Jennifer
Boerwinkle, Eric
Franceschini, No ...
Ardissino, Diego
show more...
Bernardinelli, L ...
Mannucci, Pier M ...
Mauri, Francesco
Merlini, Piera A ...
Absher, Devin
Assimes, Themist ...
Fortmann, Stephe ...
Iribarren, Carlo ...
Knowles, Joshua ...
Quertermous, Tho ...
Ferrucci, Luigi
Tanaka, Toshiko
Bis, Joshua C.
Furberg, Curt D.
Haritunians, Tal ...
McKnight, Barbar ...
Psaty, Bruce M.
Taylor, Kent D.
Thacker, Evan L.
Almgren, Peter
Groop, Leif
Ladenvall, Claes
Boehnke, Michael
Jackson, Anne U.
Mohlke, Karen L.
Stringham, Heath ...
Tuomilehto, Jaak ...
Benjamin, Emelia ...
Hwang, Shih-Jen
Levy, Daniel
Preis, Sarah Ros ...
Vasan, Ramachand ...
Duan, Jubao
Gejman, Pablo V.
Levinson, Dougla ...
Sanders, Alan R.
Shi, Jianxin
Lips, Esther H.
Mckay, James D.
Agudo, Antonio
Barzan, Luigi
Bencko, Vladimir
Benhamou, Simone
Castellsague, Xa ...
Canova, Cristina
Conway, David I.
Fabianova, Eleon ...
Foretova, Lenka
Janout, Vladimir
Healy, Claire M.
Holcatova, Ivana
Kjaerheim, Krist ...
Lagiou, Pagona
Lissowska, Jolan ...
Lowry, Ray
Macfarlane, Tati ...
Mates, Dana
Richiardi, Loren ...
Rudnai, Peter
Szeszenia-Dabrow ...
Zaridze, David
Znaor, Ariana
Lathrop, Mark
Brennan, Paul
Bandinelli, Stef ...
Frayling, Timoth ...
Guralnik, Jack M ...
Milaneschi, Yuri
Perry, John R. B ...
Altshuler, David
Elosua, Roberto
Kathiresan, Sek
Lucas, Gavin
Melander, Olle
O'Donnell, Chris ...
Salomaa, Veikko
Schwartz, Stephe ...
Voight, Benjamin ...
Penninx, Brenda ...
Smit, Johannes H ...
Vogelzangs, Nico ...
Boomsma, Dorret ...
de Geus, Eco J. ...
Vink, Jacqueline ...
Willemsen, Gonne ...
Chanock, Stephen ...
Gu, Fangyi
Hankinson, Susan ...
Hunter, David J.
Hofman, Albert
Tiemeier, Hennin ...
Uitterlinden, An ...
van Duijn, Corne ...
Walter, Stefan
Chasman, Daniel ...
Everett, Brendan ...
Pare, Guillaume
Ridker, Paul M.
Li, Ming D.
Maes, Hermine H.
Audrain-McGovern ...
Posthuma, Daniel ...
Thornton, Laura ...
Lerman, Caryn
Kaprio, Jaakko
Rose, Jed E.
Ioannidis, John ...
Kraft, Peter
Lin, Dan-Yu
Sullivan, Patric ...
show less...
About the subject
MEDICAL AND HEALTH SCIENCES
MEDICAL AND HEAL ...
and Clinical Medicin ...
and Cardiac and Card ...
MEDICAL AND HEALTH SCIENCES
MEDICAL AND HEAL ...
and Clinical Medicin ...
and Endocrinology an ...
Articles in the publication
Nature Genetics
By the university
Lund University

Search outside SwePub

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Close

Copy and save the link in order to return to this view