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- Jondal, M, et al.
(författare)
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Thymocyte apoptosis by glucocorticoids and cAMP
- 1995
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Ingår i: Current topics in microbiology and immunology. - Berlin, Heidelberg : Springer Berlin Heidelberg. - 0070-217X. ; 200, s. 67-79
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Tidskriftsartikel (refereegranskat)
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- McConkey, DJ, et al.
(författare)
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Signal transduction pathways in apoptosis
- 1996
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Ingår i: Stem cells (Dayton, Ohio). - : Oxford University Press (OUP). - 1066-5099 .- 1549-4918. ; 14:6, s. 619-631
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Tidskriftsartikel (refereegranskat)
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6. |
- McConkey, DJ, et al.
(författare)
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The role of calcium in the regulation of apoptosis
- 1996
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Ingår i: Journal of leukocyte biology. - : Oxford University Press (OUP). - 0741-5400 .- 1938-3673. ; 59:6, s. 775-783
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Tidskriftsartikel (refereegranskat)abstract
- The recognition that apoptosis is regulated by an evolutionarily conserved set of polypeptides from the nematode Caenorhabditis elegant to humans suggests that a conserved set of biochemical mechanism(s) may also be involved in the response. Work from a number of independent laboratories suggests that alterations in cytosolic Ca2+ homeostasis represent one such candidate mechanism, and molecular targets for Ca2+ are now being identified. This review will summarize what is known about the role of Ca2+ in the regulation of apoptosis and discuss how Ca2+ might interact with some of the other biochemical signals implicated in cell death.
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