| 1. |
- Candefjord, Stefan, 1981, et al.
(författare)
-
Microwave technology for detecting traumatic intracranial bleedings: tests on phantom of subdural hematoma and numerical simulations
- 2017
-
Ingår i: Medical and Biological Engineering and Computing. - : Springer Science and Business Media LLC. - 1741-0444 .- 0140-0118. ; 55:8, s. 1177-1188
-
Tidskriftsartikel (refereegranskat)abstract
- Traumatic brain injury is the leading cause of death and severe disability for young people and a major public health problem for elderly. Many patients with intracranial bleeding are treated too late, because they initially show no symptoms of severe injury and are not transported to a trauma center. There is a need for a method to detect intracranial bleedings in the prehospital setting. In this study, we investigate whether broadband microwave technology (MWT) in conjunction with a diagnostic algorithm can detect subdural hematoma (SDH). A human cranium phantom and numerical simulations of SDH are used. Four phantoms with SDH 0, 40, 70 and 110 mL are measured with a MWT instrument. The simulated dataset consists of 1500 observations. Classification accuracy is assessed using fivefold cross-validation, and a validation dataset never used for training. The total accuracy is 100 and 82–96 % for phantom measurements and simulated data, respectively. Sensitivity and specificity for bleeding detection were 100 and 96 %, respectively, for the simulated data. SDH of different sizes is differentiated. The classifier requires training dataset size in order of 150 observations per class to achieve high accuracy. We conclude that the results indicate that MWT can detect and estimate the size of SDH. This is promising for developing MWT to be used for prehospital diagnosis of intracranial bleedings.
|
|
| 2. |
- Candefjord, Stefan, 1981, et al.
(författare)
-
Microwave technology for localization of traumatic intracranial bleedings—a numerical simulation study
- 2013
-
Ingår i: Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS. - 1557-170X. - 9781457702167 ; , s. 1948-1951
-
Konferensbidrag (refereegranskat)abstract
- Traumatic brain injury (TBI) is a major public health problem worldwide. Intracranial bleedings represents the most serious complication of TBI and need to be surgically evacuated promptly to save lives and mitigate injury. Microwave technology (MWT) is promising as a complement to computed tomography (CT) to be used in road and air ambulances for early detection of intracranial bleedings. In this study, we perform numerical simulations to investigate if a classification algorithm based on singular value decomposition can distinguish between bleedings at different positions adjacent to the skull bone for a similar but simplified problem. The classification accuracy is 94-100% for all classes, a result that encourages us to pursue our efforts with MWT for more realistic scenarios. This indicates that MWT has potential for localizing a detected bleeding, which would increase the diagnostic value of this technique.
|
|
| 3. |
|
|
| 4. |
|
|
| 5. |
- Dobsicek Trefna, Hana, 1979, et al.
(författare)
-
Detection of wood decay by microwaves
- 2015
-
Ingår i: Progress in Electromagnetics Research Symposium, PIERS 2015,Prague.. - 1559-9450.
-
Konferensbidrag (refereegranskat)
|
|
| 6. |
- Fhager, Andreas, 1976, et al.
(författare)
-
Microwave Technology in Medical Diagnostics and Treatment
- 2015
-
Ingår i: 2015 Ieee Mtt-S International Microwave Workshop Series on Rf and Wireless Technologies for Biomedical and Healthcare Applications. - New York : Ieee. - 9781479985432 ; , s. 133-134
-
Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- There is a great need for novel diagnostics and treatment tools in today's healthcare. In this paper we describe our development and progress in novel microwave based diagnostics and treatment applications. The target applications are stroke diagnostics, breast cancer detection and microwave hyperthermia.
|
|
| 7. |
- Fhager, Andreas, 1976, et al.
(författare)
-
Stroke diagnostics with a microwave helmet
- 2013
-
Ingår i: 2013 7th European Conference on Antennas and Propagation, EuCAP 2013. - 2164-3342. - 9788890701832 ; , s. 845-846
-
Konferensbidrag (refereegranskat)abstract
- In this paper we describe a microwave based measurement setup for detection and diagnostics of stroke. Results and experience from clinical testing is reported.
|
|
| 8. |
- Jian, Qiuchi, 1984, et al.
(författare)
-
Detection of breathing and heartbeat by using a simple UWB radar system
- 2014
-
Ingår i: 8th European Conference on Antennas and Propagation, EuCAP 2014. - 2164-3342. - 9788890701849 ; , s. 3078-3081
-
Konferensbidrag (refereegranskat)abstract
- We present the development on an ultra-wideband (UWB) radar system and its signal processing algorithms for detecting human breathing and heartbeat in the paper. The UWB radar system consists of two (Tx and Rx) antennas and one compact CMOS UWB transceiver. Several signal processing techniques are developed for the application. The system has been tested by real measurements. .
|
|
| 9. |
- Persson, Mikael, 1959, et al.
(författare)
-
Microwave based diagnostics and treatment in practice
- 2013
-
Ingår i: 2013 IEEE MTT-S International Microwave Workshop Series on RF and Wireless Technologies for Biomedical and Healthcare Applications, IMWS-BIO 2013 - Proceedings.
-
Konferensbidrag (refereegranskat)abstract
- Globally, around 15 million people each year suffer a stroke. Only a small fraction of stroke patients who could benefit from thrombolytic treatment reach diagnosis and treatment in time. To increase this low figure we have developed microwave technology aiming to differentiate hemorrhagic from ischemic stroke patients. The standard method for breast cancer diagnosis today is X-ray mammography. Despite its recognized ability to detect tumors it suffers from some limitations. Neither the false positive nor the false negative detection rates are negligible. An interesting alternative being researched extensively today is microwave tomography. In our current strive to develop a clinical prototype we have found that the most suitable design consists of an antenna array placed in a full 3D pattern. During the last decade clinical studies have demonstrated the ability of microwave hyperthermia to dramatically enhance cancer patient survival. The fundamental challenge is to adequately heat deep-seated tumors while preventing surrounding healthy tissue from undesired heating and damage. We are specifically addressing the challenge to deliver power levels with spatial control, patient treatment planning, and noninvasive temperature measurements. © 2013 IEEE.
|
|
| 10. |
- Persson, Mikael, 1959, et al.
(författare)
-
Microwave-Based Stroke Diagnosis Making Global Prehospital Thrombolytic Treatment Possible
- 2014
-
Ingår i: IEEE Transactions on Biomedical Engineering. - : Institute of Electrical and Electronics Engineers (IEEE). - 0018-9294 .- 1558-2531. ; 61:11, s. 2806-2817
-
Tidskriftsartikel (refereegranskat)abstract
- Here, we present two different brain diagnostic devices based on microwave technology and the associated two first proof-of-principle measurements that show that the systems can differentiate hemorrhagic from ischemic stroke in acute stroke patients, as well as differentiate hemorrhagic patients from healthy volunteers. The system was based on microwave scattering measurements with an antenna system worn on the head. Measurement data were analyzed with a machine-learning algorithm that is based on training using data from patients with a known condition. Computer tomography images were used as reference. The detection methodology was evaluated with the leave-one-out validation method combined with a Monte Carlo-based bootstrap step. The clinical motivation for this project is that ischemic stroke patients may receive acute thrombolytic treatment at hospitals, dramatically reducing or abolishing symptoms. A microwave system is suitable for prehospital use, and therefore has the potential to allow significantly earlier diagnosis and treatment than today.
|
|
