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- Ademuyiwa, Adesoji O., et al.
(författare)
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Determinants of morbidity and mortality following emergency abdominal surgery in children in low-income and middle-income countries
- 2016
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Ingår i: BMJ Global Health. - : BMJ Publishing Group Ltd. - 2059-7908. ; 1:4
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Tidskriftsartikel (refereegranskat)abstract
- Background: Child health is a key priority on the global health agenda, yet the provision of essential and emergency surgery in children is patchy in resource-poor regions. This study was aimed to determine the mortality risk for emergency abdominal paediatric surgery in low-income countries globally.Methods: Multicentre, international, prospective, cohort study. Self-selected surgical units performing emergency abdominal surgery submitted prespecified data for consecutive children aged <16 years during a 2-week period between July and December 2014. The United Nation's Human Development Index (HDI) was used to stratify countries. The main outcome measure was 30-day postoperative mortality, analysed by multilevel logistic regression.Results: This study included 1409 patients from 253 centres in 43 countries; 282 children were under 2 years of age. Among them, 265 (18.8%) were from low-HDI, 450 (31.9%) from middle-HDI and 694 (49.3%) from high-HDI countries. The most common operations performed were appendectomy, small bowel resection, pyloromyotomy and correction of intussusception. After adjustment for patient and hospital risk factors, child mortality at 30 days was significantly higher in low-HDI (adjusted OR 7.14 (95% CI 2.52 to 20.23), p<0.001) and middle-HDI (4.42 (1.44 to 13.56), p=0.009) countries compared with high-HDI countries, translating to 40 excess deaths per 1000 procedures performed.Conclusions: Adjusted mortality in children following emergency abdominal surgery may be as high as 7 times greater in low-HDI and middle-HDI countries compared with high-HDI countries. Effective provision of emergency essential surgery should be a key priority for global child health agendas.
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| 2. |
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| 3. |
- Thomas, HS, et al.
(författare)
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- 2019
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swepub:Mat__t
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| 4. |
- Glaser, Christian, et al.
(författare)
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Deep learning reconstruction of the neutrino energy with a shallow Askaryan detector
- 2022
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Ingår i: 37th International Cosmic Ray Conference, ICRC2021. - Trieste, Italy : Proceedings of Science.
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Konferensbidrag (refereegranskat)abstract
- Cost effective in-ice radio detection of neutrinos above a few 10(16) eV has been explored successfully in pilot-arrays. Alarge radio detector is currently being constructed in Greenland with the potential to measure the first cosmogenic neutrino, and an order-of-magnitude more sensitive detector is being planned with IceCube-Gen2. We present the first end-to-end reconstruction of the neutrino energy from radio detector data. NuRadioMC was used to create a large data set of 40 million events of expected radio signals that are generated via the Askaryan effect following a neutrino interaction in the ice for a broad range of neutrino energies between 100 PeV and 10 EeV. We simulated the voltage traces that would be measured by the five antennas of a shallow detector station in the presence of noise. We designed and trained a deep neural network to determine the shower energy directly from the simulated experimental data and achieve a resolution better than a factor of two (STD < 0.3 in log10(E)) which is below the irreducible uncertainty from inelasticity fluctuations. We present the model architecture and study the dependence of the resolution on event parameters. This method will enable Askaryan detectors to measure the neutrino energy.
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