| 1. |
|
|
| 2. |
- Hällström, Waldemar, et al.
(författare)
-
Fifteen-Piconewton Force Detection from Neural Growth Cones Using Nanowire Arrays
- 2010
-
Ingår i: Nano Letters. - : American Chemical Society (ACS). - 1530-6992 .- 1530-6984. ; 10:3, s. 782-787
-
Tidskriftsartikel (refereegranskat)abstract
- We used epitaxially grown monodisperse nanowire arrays to measure cellular forces with a spatial resolution of 1 mu m. Nerve cells were cultured on the array and cellular forces were calculated from the displacement of the nanowire tips. The measurements were done in situ on live cells using confocal microscopy, Forces down to 15 pN were measured on neural growth cones, showing that this method can be used to study the Fine details of growth-cone dynamics.
|
|
| 3. |
- Hällström, Waldemar, et al.
(författare)
-
Gallium phosphide nanowires as a substrate for cultured neurons
- 2007
-
Ingår i: Nano Letters. - : American Chemical Society (ACS). - 1530-6992 .- 1530-6984. ; 7:10, s. 2960-2965
-
Tidskriftsartikel (refereegranskat)abstract
- Dissociated sensory neurons were cultured on epitaxial gallium phosphide (GaP) nanowires grown vertically from a gallium phosphide surface. Substrates covered by 2.5 mu m long, 50 nm wide nanowires supported cell adhesion and axonal outgrowth. Cell survival was better on nanowire substrates than on planar control substrates. The cells interacted closely with the nanostructures, and cells penetrated by hundreds of wires were observed as well as wire bending due to forces exerted by the cells.
|
|
| 4. |
|
|
| 5. |
|
|
| 6. |
|
|
| 7. |
- Johansson, Fredrik, et al.
(författare)
-
Nanomodified surfaces and guidance of nerve cell processes
- 2008
-
Ingår i: Journal of Vacuum Science and Technology B. - : American Vacuum Society. - 1520-8567 .- 1071-1023. ; 26:6, s. 2558-2561
-
Konferensbidrag (refereegranskat)abstract
- Axonal growth and guidance were studied on different micro- and nanostructured surfaces. Nanoimprinted grooves in a polymer, epitaxial III/V nanowires, porous silicon patterns, and chemically altered surfaces were all shown to induce axonal guidance. Neurons were also found to be able to attach and grow on gallium phosphide nanowires without compromising cell survival. The results are important for the construction of a new generation of neuroelectrical interfaces, including high spatial resolution electrodes. The advantages of the different nanostructured surfaces are discussed.
|
|
| 8. |
- Prinz, Christelle, et al.
(författare)
-
Axonal guidance on patterned free-standing nanowire surfaces
- 2008
-
Ingår i: Nanotechnology. - : IOP Publishing. - 0957-4484 .- 1361-6528. ; 19:34
-
Tidskriftsartikel (refereegranskat)abstract
- We demonstrate high-fidelity guidance of axons using rows of nanowires. The axons are prevented from crossing the rows, making it possible to guide and sort a large number of axons as opposed to when chemical patterns are used. Focal adhesion forms at the nanowires establishing a possible site of information transfer between the surface and the cells. Rows of gallium phosphide (GaP) nanowires were epitaxially grown on GaP(111) substrates in patterns defined by electron beam lithography.
|
|
| 9. |
|
|
| 10. |
|
|
