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Sökning: WFRF:(Morris T) > Mittuniversitetet

  • Resultat 1-3 av 3
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1.
  • Middeldorp, Christel M., et al. (författare)
  • The Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia : design, results and future prospects
  • 2019
  • Ingår i: European Journal of Epidemiology. - : Springer Science and Business Media LLC. - 0393-2990 .- 1573-7284. ; 34:3, s. 279-300
  • Tidskriftsartikel (refereegranskat)abstract
    • The impact of many unfavorable childhood traits or diseases, such as low birth weight and mental disorders, is not limited to childhood and adolescence, as they are also associated with poor outcomes in adulthood, such as cardiovascular disease. Insight into the genetic etiology of childhood and adolescent traits and disorders may therefore provide new perspectives, not only on how to improve wellbeing during childhood, but also how to prevent later adverse outcomes. To achieve the sample sizes required for genetic research, the Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia were established. The majority of the participating cohorts are longitudinal population-based samples, but other cohorts with data on early childhood phenotypes are also involved. Cohorts often have a broad focus and collect(ed) data on various somatic and psychiatric traits as well as environmental factors. Genetic variants have been successfully identified for multiple traits, for example, birth weight, atopic dermatitis, childhood BMI, allergic sensitization, and pubertal growth. Furthermore, the results have shown that genetic factors also partly underlie the association with adult traits. As sample sizes are still increasing, it is expected that future analyses will identify additional variants. This, in combination with the development of innovative statistical methods, will provide detailed insight on the mechanisms underlying the transition from childhood to adult disorders. Both consortia welcome new collaborations. Policies and contact details are available from the corresponding authors of this manuscript and/or the consortium websites.
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2.
  • Ziegler, K., et al. (författare)
  • The synthesis of matrices of embedded semiconducting nanowires
  • 2004
  • Ingår i: Faraday discussions. - : Royal Society of Chemistry (RSC). - 1359-6640 .- 1364-5498. ; 125, s. 311-326
  • Tidskriftsartikel (refereegranskat)abstract
    • In this work we report how single crystal nanowires can be assembled into regular arrays using mesoporous thin films to define the architecture. Mesoporous thin films were prepared by a sol-gel method. These provide films of very regular structure and dimensions. The films produced in this way have almost single crystal like structures and can also exhibit strong epitaxy to the underlying silicon substrate. The films are subjected to a supercritical fluid (SCF) environment in which a precursor is decomposed to yield nanowires of metals, semiconductors or oxides. Using these SCF conditions, pore filling is complete and the products are nanowires which are single crystals and structurally aligned in one direction. The growth mechanism of the nanowires is described and size effects discussed.
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3.
  • Crowley, T.A., et al. (författare)
  • Synthesis of metal and metal oxide nanowires and nanotube arrays within a mesoporous silica template
  • 2003
  • Ingår i: Chemistry of Materials. - : American Chemical Society (ACS). - 0897-4756 .- 1520-5002. ; 15:18, s. 3518-3522
  • Tidskriftsartikel (refereegranskat)abstract
    • Metallic nanowires of cobalt, copper, and iron oxide magnetite (Fe3O4) have been synthesized within the pores of mesoporous silica using a supercritical fluid inclusion technique. The mesoporous matrix provides a means of producing a high density of stable, hexagonally ordered arrays of highly crystalline nanowires. The formation of the metal and metal oxide nanowires within the silica mesopores was confirmed by transmission electron microscopy (TEM), N2 adsorption experiments, and powder X-ray diffraction (PXRD). The mechanism of nanowire formation within the mesopores appears to occur through the initial binding and coating of the pore walls with the metal atoms to form tubelike structures within the mesoporous template. The thickness of these tubes subsequently increases with further metal deposition until nanowires are formed. Additionally, the crystal structure of the cobalt nanowires formed within the mesoporous template can be readily changed by manipulating the density of the supercritical fluid phase.  
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  • Resultat 1-3 av 3

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