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  • Ferrannini, Giulia, et al. (författare)
  • Antiphospholipid antibodies in patients with dysglycaemia : A neglected cardiovascular risk factor?
  • 2020
  • Ingår i: Diabetes & Vascular Disease Research. - : SAGE PUBLICATIONS LTD. - 1479-1641 .- 1752-8984. ; 17:3
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: Cardiovascular disease is a serious complication in patients with dysglycaemia, defined as either type 2 diabetes or impaired glucose tolerance. Research focusing on the identification of potential markers for atherothrombotic disease in these subjects is warranted. The antiphospholipid syndrome is a common acquired prothrombotic condition, defined by a combination of thrombotic events and/or obstetric morbidity and positivity of specific antiphospholipid antibodies. Available information on antiphospholipid antibodies in dysglycaemia is scarce. Objective: This study investigates the association between antiphospholipid antibodies and dysglycaemia. Patients/Methods: The PAROKRANK (periodontitis and its relation to coronary artery disease) study included 805 patients, investigated 6-10 weeks after a first myocardial infarction, and 805 matched controls. Participants without known diabetes (91%) underwent an oral glucose tolerance test. Associations between antiphospholipid antibodies (anti-cardiolipin and anti-beta 2 glycoprotein-I IgG, IgM and IgA) and dysglycaemia were analysed. Results: In total, 137 (9%) subjects had previously known type 2 diabetes and 371 (23%) newly diagnosed dysglycaemia. Compared with the normoglycaemic participants, those with dysglycaemia had a higher proportion with first myocardial infarction (61% vs 45%,p < 0.0001) and were more often antiphospholipid antibody IgG positive (8% vs 5%;p = 0.013). HbA1c, fasting glucose and 2-h glucose were significantly associated to antiphospholipid antibody IgG. Odds ratios (ORs) were 1.04 (95% confidence interval [CI] 1.02-1.06), 1.14 (95% CI 1.00 - 1.27) and 1.12 (95% CI 1.04 - 1.21), respectively, after adjustments for age, gender and smoking. Conclusions: This study reports an association between antiphospholipid antibody IgG positivity and dysglycaemia. Further studies are needed to verify these findings and to investigate if antithrombotic therapy reduces vascular complications in antiphospholipid antibody positive subjects with dysglycaemia.
  • Johansson, Kerstin, 1963- (författare)
  • Bli vuxen i arbetarstad : fem ungdomar berättar om skola, arbete och det egna livet
  • 2003
  • Doktorsavhandling (övrigt vetenskapligt)abstract
    • In this dissertation, the lives of five young people living in Norrköping follows for five years (1998 – 2002) through fieldwork involving observations and recurring interviews.The objective of the study is to describe and analyse the development into adulthood and the creation of a (cultural) identity among a group of young people in a town, which used to be heavily working class. The objective is also to relate this to gender and class, institutional practices, the cultural legacy and changes in society.Primarily qualitative sociological research methods have been applied in the study. Ideas about social interaction and social processes derived from symbolic interactionism constitute one of the scientific foundations of the study.The study deals with the three key transitions; education, work and personal life. These transitions, which are essential to attaining adulthood, are emphasised and problematised in the study.In this study we can see that the process of individualisation in modern society has, in the context of the development of young people into adulthood, taken the form of a stream of messages to which they relate and in which society has, via institutional practices and rhetoric, played an active role. Factors such as gender, class and culture have constituted the conditions for the individualisation process. The mixed messages received by these young people have been representative of the discrepancy between general career possibilities and the actual opportunities which the youths in the study have encountered. These mixed messages have been mediated, as biographical schemes, at home (by parents), at school, in the context of institutional practices and, not least, via local politics, local media and in literature about the town.In its conclusion, this study points out that political and public discourse in Norrköping constitutes a bearer and “preserver” of a patriarchal tradition which contributes to preserving the negative image of the working-class town of Norrköping.
  • Krekula, Clary, 1959-, et al. (författare)
  • Ålder i intersektionell analys
  • 2005
  • Ingår i: Kvinnovetenskaplig tidskrift. - 0348-8365. ; :2-3, s. 81-94-
  • Tidskriftsartikel (refereegranskat)
  • Nyström, Anne-Sofie, 1974- (författare)
  • Att synas och lära utan att synas lära : en studie om underprestation och privilegierade unga mäns identitetsförhandlingar i gymnasieskolan
  • 2012
  • Doktorsavhandling (övrigt vetenskapligt)abstract
    • In the last decade stratification within educational results has, in Sweden as in other countries, been framed as a matter of boys’ and young men’s under-achievement. The question of whether this is a problem, and if so, for whom and how to change the structure, has been discussed in research and educational policy. The aim of the thesis is to contribute to these fields and to enhance knowledge of young people’s gendered and classed identity processes, by analyzing how achievement and engagement were negotiated and given meaning in relation to young men. Previous research has primarily explored identity processes among “risk categories” or subordinated students. The objective here was to analyze how masculinity was accomplished via peer-group interactions within a rarely problematized category, through examining how upper middle-class young men identify themselves and are ascribed identities by others.The study’s design was inspired by ethnographic methodology and combined participant observation, semi-structured individual and group interviews and a background questionnaire. Identities, social categorizations (especially gender and class) and dominance-relations were thus analyzed from an actor-oriented perspective. The research participants were young men and women, age 15-16, in two school classes. The field work was conducted at, respectively, a Natural Science and a Vehicle Programme; educational settings with connotations to masculinity but significantly different in terms of class. The study enrolled a total of fifty-six students, but focus is upon the fifteen young men among the natural science students. High achievement and under-achievement, high social and cognitive ability, and group loyalty are main themes in the study. Identity claims were analyzed in relation to the practices through which they were negotiated, e.g. self-hindrance. Similar to other research, the results emphasize the relationship between masculinity and “effortless achievement”. The concept “under-achievement” is developed as an analytical tool, by distinguishing between five dimensions.
  • Närvänen, Anna-Liisa, et al. (författare)
  • Childhood as generation or life phase?
  • 2004
  • Ingår i: Young. - : Sage Publications. - 1103-3088 .- 1741-3222. ; 12:1, s. 91-111
  • Tidskriftsartikel (refereegranskat)
  • Alexanderson, Karin, 1952-, et al. (författare)
  • Att se barn som anhöriga
  • 2015
  • Ingår i: Att se barn som anhöriga. - Kalmar och Växjö : Nationells komptenscentrum anhöriga och Linnéuniversitetet. - 9789187731266 ; , s. 21-42
  • Bokkapitel (refereegranskat)
  • Alexanderson, Karin, 1952-, et al. (författare)
  • Barn som anhöriga, utsatta och omvårdare - två typexempel
  • 2015
  • Ingår i: Att se barn som anhöriga<em> </em>. - Kalmar och Växjö : Nationellt kompetenscentrum anhöriga och Linneuniversitetet. - 9789187731266 ; , s. 345-366
  • Bokkapitel (refereegranskat)
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