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| 2. |
- Bylesjö, Max, et al.
(författare)
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Integrated analysis of transcript, protein and metabolite data to study lignin biosynthesis in hybrid aspen
- 2009
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Ingår i: Journal of Proteome Research. - : American Chemical Society (ACS). - 1535-3893 .- 1535-3907. ; 8:1, s. 199-210
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Tidskriftsartikel (refereegranskat)abstract
- Tree biotechnology will soon reach a mature state where it will influence the overall supply of fiber, energy and wood products. We are now ready to make the transition from identifying candidate genes, controlling important biological processes, to discovering the detailed molecular function of these genes on a broader, more holistic, systems biology level. In this paper, a strategy is outlined for informative data generation and integrated modeling of systematic changes in transcript, protein and metabolite profiles measured from hybrid aspen samples. The aim is to study characteristics of common changes in relation to genotype-specific perturbations affecting the lignin biosynthesis and growth. We show that a considerable part of the systematic effects in the system can be tracked across all platforms and that the approach has a high potential value in functional characterization of candidate genes.
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| 3. |
- De Palma, Adriana, et al.
(författare)
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Predicting bee community responses to land-use changes : effects of geographic and taxonomic biases
- 2016
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Ingår i: Scientific Reports. - : Nature Publishing Group. - 2045-2322. ; 6, s. 1-14
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Tidskriftsartikel (refereegranskat)abstract
- Land-use change and intensification threaten bee populations worldwide, imperilling pollination services. Global models are needed to better characterise, project, and mitigate bees' responses to these human impacts. The available data are, however, geographically and taxonomically unrepresentative; most data are from North America and Western Europe, overrepresenting bumblebees and raising concerns that model results may not be generalizable to other regions and taxa. To assess whether the geographic and taxonomic biases of data could undermine effectiveness of models for conservation policy, we have collated from the published literature a global dataset of bee diversity at sites facing land-use change and intensification, and assess whether bee responses to these pressures vary across 11 regions (Western, Northern, Eastern and Southern Europe; North, Central and South America; Australia and New Zealand; South East Asia; Middle and Southern Africa) and between bumblebees and other bees. Our analyses highlight strong regionally-based responses of total abundance, species richness and Simpson's diversity to land use, caused by variation in the sensitivity of species and potentially in the nature of threats. These results suggest that global extrapolation of models based on geographically and taxonomically restricted data may underestimate the true uncertainty, increasing the risk of ecological surprises.
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| 4. |
- Eklund, Ann, et al.
(författare)
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Times of trouble—seasonal variation in number and severity of attacks on sheep caused by large carnivores and eagles in Sweden
- 2024
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Ingår i: European Journal of Wildlife Research. - 1612-4642 .- 1439-0574. ; 70
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Tidskriftsartikel (refereegranskat)abstract
- Wildlife managers and livestock owners can choose from a multitude of interventions to prevent carnivore attacks on domestic animals, ranging from light and sound deterrents to fencing and lethal control. To guide management and make the best and most cost-effective choice of interventions, knowledge about where and when these measures are needed the most is important. By identifying spatiotemporal patterns of carnivore attacks, resources can be used more efficiently to prevent such attacks. We used a Swedish nationwide, long-term data set to identify inter- and intra-seasonal variation in probability, number, and severity (number of killed or injured per attack) of large carnivore attacks on sheep. Our results show that there are specific “times of trouble”, regarding the number of attacks from golden eagle (Aquila chrysaetos) in late spring, and from brown bears (Ursus arctos), lynx (Lynx lynx), and wolves (Canis lupus) in late summer. Additionally, for brown bears and wolves, the severity of attacks varied throughout the grazing season with a peak in the latter part of the summer. The results can be used for guidance of temporal prioritisation of preventive interventions to reduce the probability, number, and severity of large carnivore attacks on sheep.
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| 5. |
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| 6. |
- Hudson, Lawrence N, et al.
(författare)
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The database of the PREDICTS (Projecting Responses of Ecological Diversity In Changing Terrestrial Systems) project
- 2017
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Ingår i: Ecology and Evolution. - : John Wiley & Sons. - 2045-7758. ; 7:1, s. 145-188
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Tidskriftsartikel (refereegranskat)abstract
- The PREDICTS project-Projecting Responses of Ecological Diversity In Changing Terrestrial Systems (www.predicts.org.uk)-has collated from published studies a large, reasonably representative database of comparable samples of biodiversity from multiple sites that differ in the nature or intensity of human impacts relating to land use. We have used this evidence base to develop global and regional statistical models of how local biodiversity responds to these measures. We describe and make freely available this 2016 release of the database, containing more than 3.2 million records sampled at over 26,000 locations and representing over 47,000 species. We outline how the database can help in answering a range of questions in ecology and conservation biology. To our knowledge, this is the largest and most geographically and taxonomically representative database of spatial comparisons of biodiversity that has been collated to date; it will be useful to researchers and international efforts wishing to model and understand the global status of biodiversity.
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| 7. |
- Johansen, I. B., et al.
(författare)
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Bigger is not better: cortisol-induced cardiac growth and dysfunction in salmonids
- 2017
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Ingår i: Journal of Experimental Biology. - : The Company of Biologists. - 0022-0949 .- 1477-9145. ; 220:14, s. 2545-2553
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Tidskriftsartikel (refereegranskat)abstract
- Stress and elevated cortisol levels are associated with pathological heart growth and cardiovascular disease in humans and other mammals. We recently established a link between heritable variation in post-stress cortisol production and cardiac growth in salmonid fish too. A conserved stimulatory effect of the otherwise catabolic steroid hormone cortisol is probably implied, but has to date not been established experimentally. Furthermore, whereas cardiac growth is associated with failure of the mammalian heart, pathological cardiac hypertrophy has not previously been described in fish. Here, we show that rainbow trout (Oncorhynchus mykiss) treated with cortisol in the diet for 45 days have enlarged hearts with lower maximum stroke volume and cardiac output. In accordance with impaired cardiac performance, overall circulatory oxygen-transporting capacity was diminished as indicated by reduced aerobic swimming performance. In contrast to the well-known adaptive/physiological heart growth observed in fish, cortisol-induced growth is maladaptive. Furthermore, the observed heart growth was associated with up-regulated signature genes of mammalian cardiac pathology, suggesting that signalling pathways mediating cortisol-induced cardiac remodelling in fish are conserved from fish to mammals. Altogether, we show that excessive cortisol can induce pathological cardiac remodelling. This is the first study to report and integrate the etiology, physiology and molecular biology of cortisol-induced pathological remodelling in fish.
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| 9. |
- Linders, Torsten, 1971, et al.
(författare)
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Distribution and fate of trawling-induced suspension of sediments in a marine protected area
- 2018
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Ingår i: ICES Journal of Marine Science. - : Oxford University Press (OUP). - 1054-3139 .- 1095-9289. ; 75:2, s. 785-795
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Tidskriftsartikel (refereegranskat)abstract
- Bottom trawls suspend sediments by physical contact and the drag created by the gear when towed over the seafloor. Increased turbidity and redistribution of sediments may be of concern as some organisms are vulnerable to increased levels of sediment particles in the water column. This study investigates the distribution and fate of trawling-induced suspension of sediments in a coastal marine protected area (MPA). Bottom trawling is allowed in a deep trench of the MPA and regulated to weekdays with weekend closures. We use the closed period as controls to experimentally investigate sediment resuspension generated by the trawling fleet. We find that the turbidity is elevated at trawled depths and originates from small particles of silt–mud seafloor origin that remain suspended for days preventing background levels to be reached during closures. Peaks in the plumes behind trawlers reach levels critical to organisms but decays within hours. Currents in the trench are too weak to resuspend sediments; however, wind-induced resuspension events of elevated turbidity likely originating from nearby shallower areas may occur. Short-term closures and small-scale MPAs are concluded to be of limited use as management tools to reduce effects of resuspension by bottom trawling.
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| 10. |
- Mills, James A., et al.
(författare)
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Archiving Primary Data : Solutions for Long-Term Studies
- 2015
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Ingår i: Trends in Ecology & Evolution. - : Elsevier BV. - 0169-5347 .- 1872-8383. ; 30:10, s. 581-589
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Tidskriftsartikel (refereegranskat)abstract
- The recent trend for journals to require open access to primary data included in publications has been embraced by many biologists, but has caused apprehension amongst researchers engaged in long-term ecological and evolutionary studies. A worldwide survey of 73 principal investigators (PIs) with long-term studies revealed positive attitudes towards sharing data with the agreement or involvement of the PI, and 93% of PIs have historically shared data. Only 8% were in favor of uncontrolled, open access to primary data while 63% expressed serious concern. We present here their viewpoint on an issue that can have non-trivial scientific consequences. We discuss potential costs of public data archiving and provide possible solutions to meet the needs of journals and researchers.
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