SwePub
Tyck till om SwePub Sök här!
Sök i SwePub databas

  Utökad sökning

Träfflista för sökning "WFRF:(Nord S) ;spr:eng"

Sökning: WFRF:(Nord S) > Engelska

  • Resultat 1-10 av 146
Sortera/gruppera träfflistan
   
NumreringReferensOmslagsbildHitta
1.
  •  
2.
  •  
3.
  •  
4.
  •  
5.
  •  
6.
  •  
7.
  •  
8.
  • Drlica-Wagner, A., et al. (författare)
  • SEARCH FOR GAMMA-RAY EMISSION FROM DES DWARF SPHEROIDAL GALAXY CANDIDATES WITH FERMI-LAT DATA
  • 2015
  • Ingår i: Astrophysical Journal Letters. - 2041-8205 .- 2041-8213. ; 809:1
  • Tidskriftsartikel (refereegranskat)abstract
    • Due to their proximity, high dark-matter (DM) content, and apparent absence of non-thermal processes, Milky Way dwarf spheroidal satellite galaxies (dSphs) are excellent targets for the indirect detection of DM. Recently, eight new dSph candidates were discovered using the first year of data from the Dark Energy Survey (DES). We searched for gamma-ray emission coincident with the positions of these new objects in six years of Fermi Large Area Telescope data. We found no significant excesses of gamma-ray emission. Under the assumption that the DES candidates are dSphs with DM halo properties similar to the known dSphs, we computed individual and combined limits on the velocity-averaged DM annihilation cross section for these new targets. If the estimated DM content of these dSph candidates is confirmed, they will constrain the annihilation cross section to lie below the thermal relic cross section for DM particles with masses less than or similar to 20 GeV annihilating via the b (b) over bar or pi(+)pi(-) channels.
  •  
9.
  • Lawrenson, Kate, et al. (författare)
  • Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locus
  • 2016
  • Ingår i: Nature Communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 7
  • Tidskriftsartikel (refereegranskat)abstract
    • A locus at 19p13 is associated with breast cancer (BC) and ovarian cancer (OC) risk. Here we analyse 438 SNPs in this region in 46,451 BC and 15,438 OC cases, 15,252 BRCA1 mutation carriers and 73,444 controls and identify 13 candidate causal SNPs associated with serous OC (P=9.2 × 10-20), ER-negative BC (P=1.1 × 10-13), BRCA1-associated BC (P=7.7 × 10-16) and triple negative BC (P-diff=2 × 10-5). Genotype-gene expression associations are identified for candidate target genes ANKLE1 (P=2 × 10-3) and ABHD8 (P<2 × 10-3). Chromosome conformation capture identifies interactions between four candidate SNPs and ABHD8, and luciferase assays indicate six risk alleles increased transactivation of the ADHD8 promoter. Targeted deletion of a region containing risk SNP rs56069439 in a putative enhancer induces ANKLE1 downregulation; and mRNA stability assays indicate functional effects for an ANKLE1 3′-UTR SNP. Altogether, these data suggest that multiple SNPs at 19p13 regulate ABHD8 and perhaps ANKLE1 expression, and indicate common mechanisms underlying breast and ovarian cancer risk.
  •  
10.
  •  
Skapa referenser, mejla, bekava och länka
  • Resultat 1-10 av 146
Typ av publikation
tidskriftsartikel (125)
konferensbidrag (19)
annan publikation (1)
bokkapitel (1)
Typ av innehåll
refereegranskat (128)
övrigt vetenskapligt/konstnärligt (18)
Författare/redaktör
Nord, CE (44)
Nord, S (18)
Nord, A (16)
Hall, P (15)
Czene, K (15)
Bolla, MK (15)
visa fler...
Margolin, S (15)
Hamann, U (15)
Schmidt, MK (15)
Mannermaa, A (15)
Lambrechts, D (15)
Chang-Claude, J (15)
Nevanlinna, H (15)
Forsberg, S (14)
Wang, Q. (14)
Michailidou, K (14)
Dunning, AM (14)
Andrulis, IL (14)
Fasching, PA (14)
Couch, FJ (14)
Kosma, VM (14)
Rudolph, A (14)
Chenevix-Trench, G (14)
Easton, DF (14)
Benitez, J. (13)
Dennis, J (13)
Giles, GG (13)
Hopper, JL (13)
Southey, MC (13)
Beckmann, MW (13)
Haiman, CA (13)
Winqvist, R (13)
Devilee, P (13)
Garcia-Closas, M (13)
Nordberg, P (12)
Ringh, M (12)
Brenner, H (12)
Lindblom, A (12)
Milne, RL (12)
Claesson, A. (12)
Broeks, A (12)
Cox, A (12)
Burwinkel, B (12)
Bojesen, SE (12)
Darabi, H (12)
Hooning, MJ (12)
Jakubowska, A (12)
Lubinski, J (12)
Flyger, H (12)
Cross, SS (12)
visa färre...
Lärosäte
Karolinska Institutet (108)
Lunds universitet (24)
Uppsala universitet (21)
Kungliga Tekniska Högskolan (6)
Linköpings universitet (5)
Stockholms universitet (4)
visa fler...
RISE (4)
Umeå universitet (3)
Göteborgs universitet (2)
Linnéuniversitetet (2)
Luleå tekniska universitet (1)
Örebro universitet (1)
Mittuniversitetet (1)
Södertörns högskola (1)
Chalmers tekniska högskola (1)
Högskolan i Borås (1)
visa färre...
Språk
Engelska (146)Ta bort avgränsningen
Forskningsämne (UKÄ/SCB)
Medicin och hälsovetenskap (31)
Naturvetenskap (24)
Teknik (4)
Samhällsvetenskap (1)

År

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy