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1.	Niemi, MEK, et al. (author) 2021 swepub:Mat__t
2.	2017 swepub:Mat__t
3.	Glasbey, JC, et al. (author) 2021 swepub:Mat__t
4.	Adamina, M, et al. (author) The impact of surgical delay on resectability of colorectal cancer: An international prospective cohort study 2022 In: Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland. - : Wiley. - 1463-1318. ; 24:6, s. 708-726 Journal article (peer-reviewed)
5.	Ramdas, S., et al. (author) A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids 2022 In: American Journal of Human Genetics. - : Elsevier BV. - 0002-9297 .- 1537-6605. ; 109:8, s. 1366-1387 Journal article (peer-reviewed)abstract A major challenge of genome-wide association studies (GWASs) is to translate phenotypic associations into biological insights. Here, we integrate a large GWAS on blood lipids involving 1.6 million individuals from five ancestries with a wide array of functional genomic datasets to discover regulatory mechanisms underlying lipid associations. We first prioritize lipid-associated genes with expression quantitative trait locus (eQTL) colocalizations and then add chromatin interaction data to narrow the search for functional genes. Polygenic enrichment analysis across 697 annotations from a host of tissues and cell types confirms the central role of the liver in lipid levels and highlights the selective enrichment of adipose-specific chromatin marks in high-density lipoprotein cholesterol and triglycerides. Overlapping transcription factor (TF) binding sites with lipid-associated loci identifies TFs relevant in lipid biology. In addition, we present an integrative framework to prioritize causal variants at GWAS loci, producing a comprehensive list of candidate causal genes and variants with multiple layers of functional evidence. We highlight two of the prioritized genes, CREBRF and RRBP1, which show convergent evidence across functional datasets supporting their roles in lipid biology.
6.	Jukema, JW, et al. (author) Alirocumab in Patients With Polyvascular Disease and Recent Acute Coronary Syndrome: ODYSSEY OUTCOMES Trial 2019 In: Journal of the American College of Cardiology. - : Elsevier BV. - 1558-3597 .- 0735-1097. ; 74:9, s. 1167-1176 Journal article (peer-reviewed)
7.	Ray, KK, et al. (author) Effects of alirocumab on cardiovascular and metabolic outcomes after acute coronary syndrome in patients with or without diabetes: a prespecified analysis of the ODYSSEY OUTCOMES randomised controlled trial 2019 In: The lancet. Diabetes & endocrinology. - 2213-8595 .- 2213-8587. ; 7:8, s. 618-628 Journal article (peer-reviewed)
8.	Roe, MT, et al. (author) Risk Categorization Using New American College of Cardiology/American Heart Association Guidelines for Cholesterol Management and Its Relation to Alirocumab Treatment Following Acute Coronary Syndromes 2019 In: Circulation. - : Ovid Technologies (Wolters Kluwer Health). - 1524-4539 .- 0009-7322. ; 140:19, s. 1578-1589 Journal article (peer-reviewed)
9.	Steg, PG, et al. (author) Effect of Alirocumab on Mortality After Acute Coronary Syndromes 2019 In: Circulation. - 1524-4539. ; 140:2, s. 103-112 Journal article (peer-reviewed)
10.	Szarek, M, et al. (author) Alirocumab Reduces Total Hospitalizations and Increases Days Alive and Out of Hospital in the ODYSSEY OUTCOMES Trial 2019 In: Circulation. Cardiovascular quality and outcomes. - : Ovid Technologies (Wolters Kluwer Health). - 1941-7705 .- 1941-7713. ; 12:11, s. e005858- Journal article (peer-reviewed)

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Type of publication: journal article (82); conference paper (1)

Type of content: peer-reviewed (80); other academic/artistic (3)

Author/Editor: Mahajan, A. (16); Melander, Olle (15); Khan, A. (13); Lind, Lars (13); Jukema, JW (13); Li, Y. (12); show more...; Kumar, P. (12); Scott, D. (12); Samani, Nilesh J. (12); Kumar, A. (11); Rosenberg, M. (11); Hankey, Graeme J. (11); Takahashi, T. (11); Anderson, J (11); Jain, D (11); Martins, D (11); Fernandez, M (11); Hall, J (11); Rotter, Jerome I. (11); Takeda, Y (11); King, M. (10); Zhang, Z. (10); Zhu, H. (10); Robinson, S. (10); Zheng, Y. (10); Das, S. (10); Diaz, R. (10); Schmidt, H. (10); Davies, R (10); Aggarwal, R. (10); Diaz, A. (10); Aboyans, V (10); Khan, M (10); White, M. (10); Katz, A. (10); Salomaa, Veikko (10); Huang, L. (10); Harris, B (10); Rao, S (10); Janik, M (10); Schmidt, R (10); Kim, C. (10); Ferrari, E. (10); Wareham, Nicholas J. (10); Park, H. (10); Paré, Guillaume (10); Collins, N (10); Reynolds, T (10); Stewart, R (10); Larsen, J (10); show less...

University: Karolinska Institutet (49); Uppsala University (37); Lund University (36); University of Gothenburg (26); Umeå University (9); Stockholm University (4); show more...; Linköping University (4); Högskolan Dalarna (4); Chalmers University of Technology (2); Swedish University of Agricultural Sciences (2); Mid Sweden University (1); show less...

Language: English (86)

Research subject (UKÄ/SCB): Medical and Health Sciences (65); Natural sciences (10); Engineering and Technology (1); Social Sciences (1); Humanities (1)

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