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- Kurth, F, et al.
(författare)
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Large-scale analysis of structural brain asymmetries during neurodevelopment : Associations with age and sex in 4265 children and adolescents.
- 2024
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Ingår i: Human Brain Mapping. - 1065-9471 .- 1097-0193. ; 45:11, s. e26754-
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Tidskriftsartikel (refereegranskat)abstract
- Only a small number of studies have assessed structural differences between the two hemispheres during childhood and adolescence. However, the existing findings lack consistency or are restricted to a particular brain region, a specific brain feature, or a relatively narrow age range. Here, we investigated associations between brain asymmetry and age as well as sex in one of the largest pediatric samples to date (n = 4265), aged 1-18 years, scanned at 69 sites participating in the ENIGMA (Enhancing NeuroImaging Genetics through Meta-Analysis) consortium. Our study revealed that significant brain asymmetries already exist in childhood, but their magnitude and direction depend on the brain region examined and the morphometric measurement used (cortical volume or thickness, regional surface area, or subcortical volume). With respect to effects of age, some asymmetries became weaker over time while others became stronger; sometimes they even reversed direction. With respect to sex differences, the total number of regions exhibiting significant asymmetries was larger in females than in males, while the total number of measurements indicating significant asymmetries was larger in males (as we obtained more than one measurement per cortical region). The magnitude of the significant asymmetries was also greater in males. However, effect sizes for both age effects and sex differences were small. Taken together, these findings suggest that cerebral asymmetries are an inherent organizational pattern of the brain that manifests early in life. Overall, brain asymmetry appears to be relatively stable throughout childhood and adolescence, with some differential effects in males and females.
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- Rona, P.A., et al.
(författare)
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Carslberg ridge and mid-atlantic ridge : slow-spreading apparent analogs
- 2005
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Ingår i: AGU, Fall Meeting. - : American Geophysical Union (AGU).
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- We compare morphology, tectonics, petrology, and hydrothermal activity of a known section of the Mid-Atlantic Ridge (MAR) between the Kane and Atlantis fracture zones (full multi-beam coverage 21N to 31N) to the lesser known Carlsberg Ridge (CR; limited multi-beam coverage plus satellite altimetry). The CR extends from the Owen Fracture Zone (10N) to the Vityaz Fracture Zone (5S) and spreads at half-rates (~1.2-1.8 cm/yr) similar to the MAR: 1) Morphology: Both ridges exhibit distinct segmentation (primarily sinistral) and axial valleys with high floor to crest relief (range 1122-1771 m). Average lengths of segments (CR: 70 km; MAR: 50 km) and crest-to crest width of the axial valley are greater on the CR (40 km) than MAR (23 km). Axial volcanic ridges form the neovolcanic zone on both ridges, typically 2.6 km wide and 213 m high on the CR. Average water depth near segment centers is greater on the MAR (3933 m) than the CR (3564 m). V-shaped patterns oblique to the spreading axis are present on both ridges. 2) Tectonics: Segments on each ridge are predominantly separated by short-offset (<30 km) non-transform discontinuities with longer transform faults generally spaced hundreds of kilometers apart. Bulls-eye Mantle Bouguer Lows (-30 to -50 mgal) are present at centers of spreading segments on both ridges. Metamorphic core complexes of lower crust and upper mantle are present on the MAR section (at fracture zones) and at least at one locality at 58.33E on the CR. 3) Petrology: MORB composition from our 20 stations along the CR fall into the MORB family, with no evidence of hotspot inputs (no excess K or Nb), or extreme fractionation, similar to the MAR section. REE and trace element patterns between 57E and 61E on the CR indicate increasing melt depletion to the northwest, while glasses exhibit a striking systematic increase in MgO (decrease in fractionation) to the northwest and attain among the most primitive composition of any ocean ridge adjacent to the Owen fracture zone (9.93wt percent). Sr, Nd, and Pb isotopic compositions of Indian Ocean MORB are distinct from those of other oceans. They exhibit relatively higher 87Sr/86Sr, and lower 143Nd/144Nd, 207Pb/204Pb and 208Pb/204Pb for a given 206Pb/204Pb invoking mixing and regional-scale contamination of a depleted mantle with a variously designated enriched reservoir (EM1, EM2, DUPAL, etc.). 4) Hydrothermal activity: The MAR section encompasses a low-T hydrothermal field driven by the serpentinization at the Atlantis fracture zone (Lost City at 30N), and three high-temperature fields driven by magmatic heat in the axial valley (Broken Spur 29N, TAG 26N, and Snake Pit 23N). A 70 km-long, 1000 m-thick megaplume was detected in the water column up to 1400 m above the CR axial valley centered at 6.05N, 60.95E in August 2003, the first clear evidence of high-temperature hydrothermal activity on the CR. Further CR hydrothermal evidence includes relict sulfide chimneys at 58E; Mn-oxide coatings on basalts in the axial valley with Fe/Mn ratios at the boundary between hydrogenous and hydrothermal composition with thickness at two stations (1.67S, 67.77E; 5.35S, 68.62E) suggestive of hydrothermal input; and a d3He anomaly (166 per mil) in the water column at one of our stations in April 1979 (5.35S, 68.62E).
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