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Träfflista för sökning "WFRF:(Ofverholm A) ;conttype:(scientificother)"

Search: WFRF:(Ofverholm A) > Other academic/artistic

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  • Ofverholm, I. Ivanov, et al. (author)
  • PROGNOSTIC IMPACT OF IKZF1 DELETIONS IN PEDIATRIC B-CELL PRECURSOR ACUTE LYMPHOBLASTIC LEUKEMIA TREATED ACCORDING TO NOPHO PROTOCOLS - THE SWEDISH EXPERIENCE
  • 2014
  • In: Haematologica. - 0390-6078 .- 1592-8721. ; 99:Suppl 1, s. 9-9
  • Journal article (other academic/artistic)abstract
    • Recently, IKZF1 deletions have been shown to be associated notonly with the leukemogenic process but also to confer a poor prognosis in allrisk groups of B-cell precursor ALL. In a previous study, we used Multiplex Ligation-dependentProbe Amplification (MLPA) to investigate the presence ofIKZF1 deletions in bone marrow DNA from 116 children diagnosed with BCPALL in a single center and treated according to NOPHO protocols. Deletionswere detected in 16% of cases; both event free survival and overall survivalwere significantly reduced in the IKZF1-deleted group compared to the groupwith intact IKZF1.
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  • Result 1-9 of 9

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