↓ Direkt till sidans innehåll
↓ Direkt till sidans sekundära innehåll (sidomenyn)

Träfflista för sökning "WFRF:(Orntoft TF) ;pers:(Nordestgaard BG)"

Search: WFRF:(Orntoft TF) > Nordestgaard BG

Result 1-6 of 6

Sort/group result

Sort by: Hits per page:

Enumeration	Reference	Cover	Find
1.	Al Olama, AA, et al. (author) A meta-analysis of genome-wide association studies to identify prostate cancer susceptibility loci associated with aggressive and non-aggressive disease 2013 In: Human molecular genetics. - : Oxford University Press (OUP). - 1460-2083 .- 0964-6906. ; 22:2, s. 408-415 Journal article (peer-reviewed)
2.	Dadaev, T, et al. (author) Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants 2018 In: Nature communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 9:1, s. 2256- Journal article (peer-reviewed)abstract Prostate cancer is a polygenic disease with a large heritable component. A number of common, low-penetrance prostate cancer risk loci have been identified through GWAS. Here we apply the Bayesian multivariate variable selection algorithm JAM to fine-map 84 prostate cancer susceptibility loci, using summary data from a large European ancestry meta-analysis. We observe evidence for multiple independent signals at 12 regions and 99 risk signals overall. Only 15 original GWAS tag SNPs remain among the catalogue of candidate variants identified; the remainder are replaced by more likely candidates. Biological annotation of our credible set of variants indicates significant enrichment within promoter and enhancer elements, and transcription factor-binding sites, including AR, ERG and FOXA1. In 40 regions at least one variant is colocalised with an eQTL in prostate cancer tissue. The refined set of candidate variants substantially increase the proportion of familial relative risk explained by these known susceptibility regions, which highlights the importance of fine-mapping studies and has implications for clinical risk profiling.
3.	Kote-Jarai, Z, et al. (author) Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study 2011 In: Nature genetics. - : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 43:8, s. 785-U96 Journal article (peer-reviewed)
4.	Matejcic, M, et al. (author) Author Correction: Germline variation at 8q24 and prostate cancer risk in men of European ancestry 2019 In: Nature communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 10:1, s. 382- Journal article (peer-reviewed)abstract The original version of this Article contained an error in the spelling of the author Manuela Gago-Dominguez, which was incorrectly given as Manuela G. Dominguez. This has now been corrected in both the PDF and HTML versions of the Article.
5.	Schumacher, FR, et al. (author) Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci 2018 In: Nature genetics. - : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 50:7, s. 928- Journal article (peer-reviewed)
6.	Schumacher, FR, et al. (author) Author Correction: Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci 2019 In: Nature genetics. - : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 51:2, s. 363-363 Journal article (peer-reviewed)

Skapa referenser, mejla, bekava och länka

Permalink

Result 1-6 of 6

Refine your search

Type of publication: journal article (6)

Type of content: peer-reviewed (6)

Author/Editor: Brenner, H (6); Riboli, E. (6); Giles, GG (6); Southey, MC (6); Nordestgaard, BG (6)Undo refine; Haiman, CA (6); show more...; Henderson, BE (6); Le Marchand, L (6); Lubinski, J (6); Easton, DF (6); Kraft, P (6); Hunter, DJ (6); John, EM (6); Gronberg, H (6); Al Olama, AA (6); Kote-Jarai, Z (6); Berndt, SI (6); Benlloch, S (6); Lindstrom, S (6); Dadaev, T (6); Tammela, TLJ (6); Schleutker, J (6); Aly, M (6); Canzian, F (6); Roder, MA (6); Thibodeau, SN (6); McDonnell, SK (6); Stanford, JL (6); Maier, C (6); Cybulski, C (6); Wokolorczyk, D (6); Lin, HY (6); Albanes, D (6); Batra, J (6); Slavov, C (6); Kaneva, R (6); Mitev, V (6); Hamdy, FC (6); Wiklund, F (6); Eeles, RA (6); Neal, DE (6); Donovan, JL (6); Ostrander, EA (6); Sorensen, KD (6); Chambers, S (6); Zhang, HW (6); Lu, YJ (6); Park, JY (6); Stern, MC (6); Orntoft, TF (6); show less...

University: Karolinska Institutet (6); Uppsala University (3)

Language: English (6)

Research subject (UKÄ/SCB): Medical and Health Sciences (3)

Year

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

Copyright © LIBRIS - National Library Systems
LIBRIS.kb.se

pil uppåt

Close

Copy and save the link in order to return to this view