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Search: WFRF:(Palmqvist Richard) > (2002-2004) > Riboli Elio

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1.	Jenab, Mazda, et al. (author) Association of nut and seed intake with colorectal cancer risk in the European Prospective Investigation into Cancer and Nutrition. 2004 In: Cancer Epidemiology Biomarkers & Prevention. - 1055-9965 .- 1538-7755. ; 13:10, s. 1595-603 Journal article (peer-reviewed)
2.	Lukanova, Annekatrin, et al. (author) Nonlinear relationship of insulin-like growth factor (IGF)-I and IGF-I/IGF-binding protein-3 ratio with indices of adiposity and plasma insulin concentrations (Sweden). 2002 In: Cancer Causes and Control. - 0957-5243 .- 1573-7225. ; 13:6, s. 509-516 Journal article (peer-reviewed)abstract OBJECTIVE: In this study we test the hypothesis of a nonlinear relationship of IGF-I with indices of body fat such as body mass index (BMI), insulin, and leptin.METHODS: The controls used in three case-control cancer studies nested in the Northern Sweden Health and Disease Cohort, were combined for this analysis. Measurements of plasma IGF-I, IGFBP-3, insulin, and leptin were available for 445 men and 391 women.RESULTS: In both men and women we found the highest mean IGF-I levels in subjects with BMI between 24 and 26. IGF-I concentrations decreased toward BMI < or = 20 and BMI > 30 in men; however, the results for women did not reach statistical significance. The molar ratio of IGF-I/IGFBP-3 showed a similar profile to that of IGF-I, although much less pronounced. The observed peak mean IGF-I levels in the second quintiles of insulin and leptin in men supported these findings. No significant variation of mean IGF-I levels across quintiles of insulin and leptin were observed in women.CONCLUSIONS: The results of this study provide evidence that IGF-I plasma concentrations vary substantially over a wide range of body weight and that the relationship is nonlinear.

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Type of publication: journal article (2)

Type of content: peer-reviewed (2)

Author/Editor: Kaaks, Rudolf (2); Riboli, Elio (2)Undo refine; Palmqvist, Richard (2); Olsen, Anja (1); Tjønneland, Anne (1); Boutron-Ruault, Mari ... (1); show more...; Clavel-Chapelon, Fra ... (1); Boeing, Heiner (1); Trichopoulou, Antoni ... (1); Krogh, Vittorio (1); Tumino, Rosario (1); Sacerdote, Carlotta (1); Norat, Teresa (1); Lundin, Eva (1); Stattin, Pär (1); Lukanova, Annekatrin (1); van Guelpen, Bethany (1); Casagrande, Corinne (1); Ardanaz, Eva (1); Palli, Domenico (1); Jenab, Mazda (1); Rinaldi, Sabina (1); Ferrari, Pietro (1); Wallström, Peter (1); Peeters, Petra H. M. (1); Hallmans, Göran (1); Martínez, Carmen (1); Bingham, Sheila (1); Quiros, Jose R. (1); Bueno-De-Mesquita, H ... (1); Dorronsoro, Miren (1); Saracci, Rodolfo (1); Naska, Androniki (1); Söderberg, Stefan (1); Slimani, Nadia (1); Kesse, Emmanuelle (1); Engeset, Dagrun (1); Nieters, Alexandra (1); Ocke, Marga C (1); Biessy, Carine (1); Bergmann, Manuela (1); Celentano, Egidio (1); Overad, Kim (1); Stripp, Connie (1); Gonzcalez, Carlos A (1); Chirlaque, Maria D (1); San Joaquin, Miguel ... (1); show less...

University: Umeå University (2); Lund University (1)

Language: English (2)

Research subject (UKÄ/SCB): Medical and Health Sciences (2)

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