Sökning: WFRF:(Palviainen Teemu)
> Naturvetenskap >
The genetic backgro...
The genetic background of the associations between sense of coherence and mental health, self-esteem and personality
-
- Silventoinen, Karri (författare)
- Karolinska Institutet
-
- Vuoksimaa, Eero (författare)
- Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, Finland
-
- Volanen, Salla-Maarit (författare)
- Folkhälsan Research Center, Helsinki, Finland ; Clinicum, Department of Public Health, University of Helsinki, Finland
-
visa fler...
-
- Palviainen, Teemu (författare)
- Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, Finland
-
- Rose, Richard J. (författare)
- Department of Psychological & Brain Sciences, Indiana University, Bloomington, USA
-
- Suominen, Sakari (författare)
- Högskolan i Skövde,Institutionen för hälsovetenskaper,Forskningsmiljön hälsa, hållbarhet och digitalisering,Department of Public Health, University of Turku, Finland,Medborgarcentrerad hälsa MeCH, Research on Citizen Centered Health, University of Skövde (Reacch US)
-
- Kaprio, Jaakko (författare)
- Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, Finland
-
visa färre...
-
(creator_code:org_t)
- 2021-05-19
- 2022
- Engelska.
-
Ingår i: Social Psychiatry and Psychiatric Epidemiology. - : Springer. - 0933-7954 .- 1433-9285. ; 57:2, s. 423-433
- Relaterad länk:
-
https://doi.org/10.1...
-
visa fler...
-
https://his.diva-por... (primary) (Raw object)
-
https://link.springe...
-
https://urn.kb.se/re...
-
https://doi.org/10.1...
-
http://kipublication...
-
visa färre...
Abstract
Ämnesord
Stäng
- PURPOSE: Sense of coherence (SOC) represents coping and can be considered an essential component of mental health. SOC correlates with mental health and personality, but the background of these associations is poorly understood. We analyzed the role of genetic factors behind the associations of SOC with mental health, self-esteem and personality using genetic twin modeling and polygenic scores (PGS).METHODS: Information on SOC (13-item Orientation of Life Questionnaire), four mental health indicators, self-esteem and personality (NEO Five Factor Inventory Questionnaire) was collected from 1295 Finnish twins at 20-27 years of age.RESULTS: In men and women, SOC correlated negatively with depression, alexithymia, schizotypal personality and overall mental health problems and positively with self-esteem. For personality factors, neuroticism was associated with weaker SOC and extraversion, agreeableness and conscientiousness with stronger SOC. All these psychological traits were influenced by genetic factors with heritability estimates ranging from 19 to 66%. Genetic and environmental factors explained these associations, but the genetic correlations were generally stronger. The PGS of major depressive disorder was associated with weaker, and the PGS of general risk tolerance with stronger SOC in men, whereas in women the PGS of subjective well-being was associated with stronger SOC and the PGSs of depression and neuroticism with weaker SOC.CONCLUSION: Our results indicate that a substantial proportion of genetic variation in SOC is shared with mental health, self-esteem and personality indicators. This suggests that the correlations between these traits reflect a common neurobiological background rather than merely the influence of external stressors.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences (hsv//eng)
- NATURVETENSKAP -- Biologi -- Genetik (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Genetics (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
Nyckelord
- Mental health
- Personality
- Polygenic score
- Sense of coherence
- Twins
- Research on Citizen Centered Health, University of Skövde (Reacch US)
- Medborgarcentrerad hälsa (Mech)
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas