↓ Direkt till sidans innehåll
↓ Direkt till sidans sekundära innehåll (sidomenyn)

Tyck till om SwePub Sök här!

Träfflista för sökning "WFRF:(Parish Sarah) ;pers:(Peto Richard)"

Search: WFRF:(Parish Sarah) > Peto Richard

Result 1-2 of 2

Sort/group result

Sort by: Hits per page:

Enumeration	Reference	Cover	Find
1.	Peden, John F., et al. (author) A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease 2011 In: Nature Genetics. - : Springer Science and Business Media LLC. - 1061-4036 .- 1546-1718. ; 43:4, s. 339-344 Journal article (peer-reviewed)abstract Genome-wide association studies have identified 11 common variants convincingly associated with coronary artery disease (CAD)(1-7), a modest number considering the apparent heritability of CAD(8). All of these variants have been discovered in European populations. We report a meta-analysis of four large genome-wide association studies of CAD, with similar to 575,000 genotyped SNPs in a discovery dataset comprising 15,420 individuals with CAD (cases) (8,424 Europeans and 6,996 South Asians) and 15,062 controls. There was little evidence for ancestry-specific associations, supporting the use of combined analyses. Replication in an independent sample of 21,408 cases and 19,185 controls identified five loci newly associated with CAD (P < 5 x 10(-8) in the combined discovery and replication analysis): LIPA on 10q23, PDGFD on 11q22, ADAMTS7-MORF4L1 on 15q25, a gene rich locus on 7q22 and KIAA1462 on 10p11. The CAD-associated SNP in the PDGFD locus showed tissue-specific cis expression quantitative trait locus effects. These findings implicate new pathways for CAD susceptibility.
2.	Armitage, Jane, et al. (author) Intensive lowering of LDL cholesterol with 80 mg versus 20 mg simvastatin daily in 12,064 survivors of myocardial infarction: a double-blind randomised trial. 2010 In: Lancet. - 1474-547X. ; 376:9753, s. 1658-69 Journal article (peer-reviewed)abstract Lowering of LDL cholesterol reduces major vascular events, but whether more intensive therapy safely produces extra benefits is uncertain. We aimed to establish efficacy and safety of more intensive statin treatment in patients at high cardiovascular risk.

Skapa referenser, mejla, bekava och länka

Permalink

Result 1-2 of 2

Refine your search

Type of publication: journal article (2)

Type of content: peer-reviewed (2)

Author/Editor: Collins, Rory (2); Armitage, Jane (2); Bowman, Louise (2); Parish, Sarah (2); Peto, Richard (2)Undo refine; Salomaa, Veikko (1); show more...; Olsson, Gunnar (1); Soranzo, Nicole (1); Axelsson, Tomas (1); Deloukas, Panos (1); Syvänen, Ann-Christi ... (1); Azhar, Muhammad (1); Hellénius, Mai-Lis (1); Clarke, Robert (1); McCarthy, Mark I (1); Franco-Cereceda, And ... (1); Eriksson, Per (1); Hamsten, Anders (1); Rasheed, Asif (1); Samuel, Maria (1); Shah, Nabi (1); Ishaq, Mohammad (1); Saleheen, Danish (1); Ripatti, Samuli (1); Tognoni, Gianni (1); Samani, Nilesh J. (1); Folkersen, Lasse (1); de Faire, Ulf (1); Peltonen, Leena (1); Froguel, Philippe (1); Lathrop, Mark (1); Wilhelmsen, Lars, 19 ... (1); Leander, Karin (1); Gigante, Bruna (1); Farrall, Martin (1); Anand, Sonia S (1); Yusuf, Salim (1); Öhrvik, John (1); Wallendszus, Karl (1); Bulbulia, Richard (1); Rahimi, Kazem (1); Haynes, Richard (1); Elliott, Paul (1); Sivapalaratnam, Suth ... (1); Hopewell, Jemma C. (1); Trip, Mieke D. (1); Watkins, Hugh (1); Kastelein, John J. P ... (1); Spector, Tim (1); Sleight, Peter (1); show less...

University: University of Gothenburg (1); Uppsala University (1); Karolinska Institutet (1)

Language: English (2)

Year

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

Copyright © LIBRIS - National Library Systems
LIBRIS.kb.se

pil uppåt

Close

Copy and save the link in order to return to this view