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Evaluating Sex and Age Differences in ADI-R and ADOS Scores in a Large European Multi-site Sample of Individuals with Autism Spectrum Disorder

Tillmann, J. (author)
King's College London
Ashwood, K. (author)
King's College London
Absoud, M. (author)
Guy's and St Thomas' NHS Foundation Trust,King's College London
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Bölte, S. (author)
Karolinska Institutet,Stockholm County Council,Karolinska Institute
Bonnet-Brilhault, F. (author)
University Of Tours
Buitelaar, J. K. (author)
Radboud University Nijmegen
Calderoni, S. (author)
University of Pisa
Calvo, R. (author)
Hospital Clínic of Barcelona
Canal-Bedia, R. (author)
University of Salamanca
Canitano, R. (author)
Azienda Ospedaliera Universitaria Senese, Siena
de Bildt, A. (author)
University Medical Center Groningen,University of Groningen
Gomot, M. (author)
University Of Tours
Hoekstra, P. J. (author)
University of Groningen
Kaale, A. (author)
Oslo university hospital,University of Oslo
McConachie, H. (author)
University of Newcastle upon Tyne
Murphy, D. G. (author)
King's College London
Narzisi, A. (author)
University of Pisa
Oosterling, I. (author)
Radboud University Nijmegen
Pejovic-Milovancevic, M. (author)
University of Belgrade
Persico, A. M. (author)
University of Messina,University Campus Bio-Medico
Puig, O. (author)
Hospital Clínic of Barcelona
Roeyers, H. (author)
Ghent University
Rommelse, N. (author)
Radboud University Nijmegen
Sacco, R. (author)
University Campus Bio-Medico
Scandurra, V. (author)
Azienda Ospedaliera Universitaria Senese, Siena
Stanfield, A. C. (author)
University of Edinburgh
Zander, E. (author)
Karolinska Institutet,Lund University,Lunds universitet,Barn- och ungdomspsykiatri,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Child and Adolescent Psychiatry,Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine,Region Skåne
Charman, T. (author)
King's College London
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 (creator_code:org_t)
2018-02-21
2018
English.
In: Journal of Autism and Developmental Disorders. - : Springer Science and Business Media LLC. - 0162-3257 .- 1573-3432. ; 48:7, s. 2490-2505
Related links:
http://dx.doi.org/10... (free)
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  • Journal article (peer-reviewed)
Abstract Subject headings
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  • Research on sex-related differences in Autism Spectrum Disorder (ASD) has been impeded by small samples. We pooled 28 datasets from 18 sites across nine European countries to examine sex differences in the ASD phenotype on the ADI-R (376 females, 1763 males) and ADOS (233 females, 1187 males). On the ADI-R, early childhood restricted and repetitive behaviours were lower in females than males, alongside comparable levels of social interaction and communication difficulties in females and males. Current ADI-R and ADOS scores showed no sex differences for ASD severity. There were lower socio-communicative symptoms in older compared to younger individuals. This large European ASD sample adds to the literature on sex and age variations of ASD symptomatology.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Psykiatri (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Psychiatry (hsv//eng)

Keyword

Age
Autism Spectrum Disorder
Phenotype
Sex
Symptom severity

Publication and Content Type

art (subject category)
ref (subject category)

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