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Träfflista för sökning "WFRF:(Petrén Mallmin M) ;hsvcat:3"

Sökning: WFRF:(Petrén Mallmin M) > Medicin och hälsovetenskap

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1.
  • Sandén, B., et al. (författare)
  • The significance of radiolucent zones surrounding pedicle screws : definition of screw loosening in spinal instrumentation
  • 2004
  • Ingår i: Journal of Bone and Joint Surgery. - 0301-620X .- 2044-5377. ; 86 B:3, s. 457-461
  • Tidskriftsartikel (refereegranskat)abstract
    • We examined the radiographs from a prospective clinical study of fixation by pedicle screws and those from an experimental study in a sheep model. In the clinical study, instruments were removed from 21 patients after implantation for 11 to 16 months and the extraction torques of the screws were recorded. A structured protocol was used for the radiological examinations. In the experimental study, loaded pedicle screw instrumentations were implanted in the sheep for six or 12 weeks. After radiological examination the pull-out resistance and the histological characteristics were studied. In the clinical study, all screws with radiolucent zones had a significantly reduced mean extraction torque compared with screws without radiolucent zones (16 +/- 10 Ncm v 403 +/- 220 Ncm; p < 0.0001). In the experimental study the mean maximum pull-out resistance for the screws with radiolucent zones was significantly lower than for those with no radiolucency (243 +/- 156 N v2214 +/- 578 N; p = 0.0006) and the mean bone-to-screw contact was reduced for screws with zones compared with those without zones (8 +/- 9% v 55 +/- 29%; p = 0.0002). Our findings showed that all screws with radiolucent zones had low extraction torques or low pull-out resistance. A radiolucent zone is a good indicator of loosening of a pedicle screw.
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2.
  • Sandén, Bengt, et al. (författare)
  • Hydroxyapatite coating improves fixation of pedicle screws : A clinical study
  • 2002
  • Ingår i: Journal of Bone and Joint Surgery. - 0301-620X .- 2044-5377. ; 84:3, s. 387-91
  • Tidskriftsartikel (refereegranskat)abstract
    • We investigated the effects of hydroxyapatite (HA) coating on the purchase of pedicle screws. A total of 23 consecutive patients undergoing lumbar fusion was randomly assigned to one of three treatment groups. The first received uncoated stainless-steel screws, the second screws which were partly coated with HA, and the third screws which were fully coated. The insertion torque was recorded. After 11 to 16 months, 21 screws had been extracted. The extraction torque was recorded. Radiographs were taken to assess fusion and to detect loosening of the screws. At removal, the extraction torques exceeded the upper limit of the torque wrench (600 Ncm) for many HA-coated screws. The calculated mean extraction torque was 29 +/- 36 Ncm for the uncoated group, 447 +/- 114 Ncm for the partly-coated group and 574 +/- 52 Ncm for the fully-coated group. There were significant differences between all three groups (p < 0.001). There were more radiolucent zones surrounding the uncoated screws than the HA-coated screws (p < 0.001). HA coating of pedicle screws resulted in improved fixation with reduced risk of loosening of the screws.
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  • Resultat 1-2 av 2
Typ av publikation
tidskriftsartikel (2)
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refereegranskat (2)
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Petrén-Mallmin, M. (2)
Larsson, Sune (1)
Larsson, C (1)
Olerud, Claes (1)
Johansson, Carina B. (1)
Sandén, B. (1)
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Sandén, Bengt (1)
Olerud, C (1)
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Lärosäte
Uppsala universitet (1)
Örebro universitet (1)
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Engelska (2)
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