SwePub
Sök i SwePub databas

  Utökad sökning

Träfflista för sökning "WFRF:(Petren A.) "

Sökning: WFRF:(Petren A.)

  • Resultat 1-10 av 16
  • [1]2Nästa
Sortera/gruppera träfflistan
   
NumreringReferensOmslagsbildHitta
1.
  •  
2.
  • Schofield, James P. R., et al. (författare)
  • Stratification of asthma phenotypes by airway proteomic signatures
  • 2019
  • Ingår i: Journal of Allergy and Clinical Immunology. - Elsevier. - 0091-6749 .- 1097-6825. ; 144:1, s. 70-82
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: Stratification by eosinophil and neutrophil counts increases our understanding of asthma and helps target therapy, but there is room for improvement in our accuracy in prediction of treatment responses and a need for better understanding of the underlying mechanisms. Objective: We sought to identify molecular subphenotypes of asthma defined by proteomic signatures for improved stratification. Methods: Unbiased label-free quantitative mass spectrometry and topological data analysis were used to analyze the proteomes of sputum supernatants from 246 participants (206 asthmatic patients) as a novel means of asthma stratification. Microarray analysis of sputum cells provided transcriptomics data additionally to inform on underlying mechanisms. Results: Analysis of the sputum proteome resulted in 10 clusters (ie, proteotypes) based on similarity in proteomic features, representing discrete molecular subphenotypes of asthma. Overlaying granulocyte counts onto the 10 clusters as metadata further defined 3 of these as highly eosinophilic, 3 as highly neutrophilic, and 2 as highly atopic with relatively low granulocytic inflammation. For each of these 3 phenotypes, logistic regression analysis identified candidate protein biomarkers, and matched transcriptomic data pointed to differentially activated underlying mechanisms. Conclusion: This study provides further stratification of asthma currently classified based on quantification of granulocytic inflammation and provided additional insight into their underlying mechanisms, which could become targets for novel therapies.
  •  
3.
  • Keleta, S, et al. (författare)
  • Exclusive measurement of two-pion production in the dd -> He-4 pi pi reaction
  • 2009
  • Ingår i: Nuclear Physics A. - 0375-9474 .- 1873-1554. ; 825:1-2, s. 71-90
  • Tidskriftsartikel (refereegranskat)abstract
    • The results from the first kinematically complete measurement of the dd -> He-4 pi pi reaction are reported. The aim was to investigate a long standing puzzle regarding the origin of the peculiar pi pi-invariant mass distributions appearing in double pion production in light ion collisions, the so-called ABC effect. The measurements were performed at the incident deuteron energies of 712 MeV and 1029 MeV. with the WASA detector assembly at CELSIUS in Uppsala, Sweden. We report the observation of a characteristic enhancement at low pi pi-invariant mass at 712 MeV, the lowest energy yet. At the higher energy, in addition to confirming previous experimental observations, Our results reveal a strong angular dependence of the pions in the overall centre of mass system. The results are qualitatively reproduced by a theoretical model, according to which the ABC effect is described as resulting from a kinematical enhancement in the production of the pion pairs from two parallel and independent NN -> d pi sub-processes. (C) 2009 Elsevier B.V. All rights reserved.
  •  
4.
  • Schonning, K., et al. (författare)
  • The pd -> He-3 eta pi(0) reaction at T-p=1450 MeV CELSIUS/WASA Collaboration
  • 2010
  • Ingår i: Physics Letters B. - 0370-2693. ; 685:1, s. 33-37
  • Tidskriftsartikel (refereegranskat)abstract
    • The cross section for the pd -> He-3 eta pi(0) reaction has been measured at a beam energy of 1450 MeV using the WASA detector at the CELSIUS storage ring. The He-3 was detected in coincidence with four photons from the decays of the two mesons. The data indicate that the production mechanism involves the formation of the Delta(1232) isobar. Although the beam energy does not allow the full peak of this resonance to be seen, the invariant mass distributions Of all three pairs of final particles are well reproduced by a phase space Monte Carlo simulation weighted with the p-wave factor of the square of the pi(0) momentum in the He-3 pi(0) system.
  •  
5.
  • Schönning, Karin, et al. (författare)
  • Production of eta and 3 pi mesons in the pd -> (HeX)-He-3 reaction at 1360 and 1450 MeV
  • 2010
  • Ingår i: European Physical Journal A. - 1434-6001 .- 1434-601X. ; 45:1, s. 11-21
  • Tidskriftsartikel (refereegranskat)abstract
    • The cross-sections of the pd -> He-3 eta, pd -> He-3 pi(0)pi(0)pi(0) and pd -> He-3 pi(+)pi(-)pi(0) reactions have been measured at the beam kinetic energies T-p = 1360 MeV and T-p = 1450 MeV using the CELSIUS/WASA detector setup. At both energies, the differential cross-section d sigma/d Omega of the eta meson in the pd -> He-3 eta reaction shows a strong forward-backward asymmetry in the CMS. The ratio between the pd -> He-3 pi(+)pi(-)pi(0) and pd -> He-3 pi(0)pi(0)pi(0) cross-sections has been analysed in terms of isospin amplitudes. The reconstructed invariant-mass distributions of the pi pi, He-3 pi and (3)He2 pi systems provide hints on the role of nucleon resonances in the 3 pi production process.
  •  
6.
  • Schönning, Karin, et al. (författare)
  • Production of the omega meson in the pd -> He-3 omega reaction at 1450 MeV and 1360 MeV
  • 2009
  • Ingår i: Physical Review C. Nuclear Physics. - 0556-2813 .- 1089-490X. ; 79:4, s. 044002
  • Tidskriftsartikel (refereegranskat)abstract
    • The production of omega mesons in the pd -> He-3 omega reaction has been studied at two energies near the kinematic threshold, T-p = 1450 MeV and T-p = 1360 MeV. The differential cross section was measured as a function of the omega c.m. angle at both energies over the whole angular range. Whereas the results at 1360 MeV are consistent with isotropy, strong rises are observed near both the forward and backward directions at 1450 MeV. Calculations made using a two-step model with an intermediate pion fail to reproduce the shapes of the measured angular distributions and also underestimate the total cross sections.
  •  
7.
  • Schönning, Karin, et al. (författare)
  • The pd →3Heηπ0 reaction at Tp = 1450 MeV
  • 2010
  • Ingår i: Physics Letters B. - 0370-2693 .- 1873-2445. ; 685:1, s. 33-37
  • Tidskriftsartikel (refereegranskat)abstract
    • The cross section for the pd→3Heηπ0 reaction has been measured at a beam energy of 1450 MeV using the WASA detector at the CELSIUS storage ring and detecting one 3He and four photons from the decays of the two mesons. The data indicate that the production mechanism involves the formation of the Δ(1232) isobar. Although the beam energy does not allow the full peak of this resonance to be seen, the invariant masses of all three pairs of final particles are well reproduce dby a phase space Monte Carlo simulation weighted with the p-wave factor of the square of the π0 momentum in the 3He π0 system.
  •  
8.
  • Skorodko, T., et al. (författare)
  • Delta Delta excitation in proton-proton induced pi(0)pi(0) production
  • 2011
  • Ingår i: Physics Letters B. - 0370-2693 .- 1873-2445. ; 695:1-4, s. 115-123
  • Tidskriftsartikel (refereegranskat)abstract
    • Exclusive measurements of the pp -> pp pi(0)pi(0) reaction have been performed at CELSIUS/WASA at energies from threshold up to T-p = 1.3 GeV. Total and differential cross sections have been obtained. Here we concentrate on energies T-p >= GeV. where the Delta Delta excitation becomes the leading process. No evidence is found for a significant ABC effect beyond that given by the conventional t-channel Delta Delta excitation. This holds also for the double-pionic fusion to the quasibound He-2. The data are compared to model predictions, which are based on both pi- and rho-exchange. Total and differential cross sections are at variance with these predictions and call for a profound modification of the rho-exchange. A phenomenological modification allowing only a small rho-exchange contribution leads to a quantitative description of the data.
  •  
9.
  • Skorodko, T., et al. (författare)
  • Exclusive measurement of the pp -> nn pi(+)pi(+) reaction at 1.1 GeV
  • 2011
  • Ingår i: European Physical Journal A. - 1434-6001 .- 1434-601X. ; 47:9, s. 108
  • Tidskriftsartikel (refereegranskat)abstract
    • First exclusive data for the pp -> nnp(+)pi(+) reaction have been obtained at CELSIUS with the WASA detector setup at a beam energy of T(p) - 1.1 GeV. Total and differential cross-sections disagree with theoretical calculations, which predict the Delta Delta excitation to be the dominant process at this beam energy. Instead, the data require the excitation of one of the nucleons to a higher-lying Delta state, preferably the Delta(1600)P(33), to be the leading process.
  •  
10.
  •  
Skapa referenser, mejla, bekava och länka
  • Resultat 1-10 av 16
  • [1]2Nästa
 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy