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Numrering	Referens	Omslagsbild	Hitta
1.	Kapelios, CJ, et al. (författare) Sacubitril/valsartan eligibility and outcomes in the ESC-EORP-HFA Heart Failure Long-Term Registry: bridging between European Medicines Agency/Food and Drug Administration label, the PARADIGM-HF trial, ESC guidelines, and real world 2019 Ingår i: European journal of heart failure. - : Wiley. - 1879-0844 .- 1388-9842. ; 21:11, s. 1383-1397 Tidskriftsartikel (refereegranskat)
2.	Toma, M, et al. (författare) Left Heart Disease Phenotype in Elderly Patients with Pulmonary Arterial Hypertension: Insights from the Italian PATRIARCA Registry 2022 Ingår i: Journal of clinical medicine. - : MDPI AG. - 2077-0383. ; 11:23 Tidskriftsartikel (refereegranskat)abstract Pulmonary arterial hypertension (PAH) in the elderly is often associated with left heart disease (LHD), prompting concerns about the use of pulmonary vasodilators. The PATRIARCA registry enrolled ≥70 year-old PAH or chronic thromboembolic pulmonary hypertension (CTEPH) patients at 11 Italian centers from 1 December 2019 through 15 September 2022. After excluding those with CTEPH, post-capillary PH at the diagnostic right heart catheterization (RHC), and/or incomplete data, 23 (33%) of a total of 69 subjects met the criteria proposed in the AMBITION trial to suspect LHD. Diabetes [9 (39%) vs. 6 (13%), p = 0.01] and chronic kidney disease [14 (61%) vs. 12 (26%), p = 0.003] were more common, and the last RHC pulmonary artery wedge pressure [14 ± 5 vs. 10 ± 3 mmHg, p < 0.001] was higher and pulmonary vascular resistance [5.56 ± 3.31 vs. 8.30 ± 4.80, p = 0.02] was lower in LHD than non-LHD patients. However, PAH therapy was similar, with 13 (57%) and 23 (50%) subjects, respectively, taking two oral drugs. PAH medication patterns remained comparable between LHD and non-LHD patients also when the former [37, 54%] were identified by atrial fibrillation and echocardiographic features of LHD, in addition to the AMBITION criteria. In this real-world snapshot, elderly PAH patients were treated with pulmonary vasodilators, including combinations, despite a remarkable prevalence of a LHD phenotype.

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Typ av publikation: tidskriftsartikel (2)

Typ av innehåll: refereegranskat (2)

Författare/redaktör: Stolfo, D (2); Bauer, F. (1); Ferrari, R. (1); Hanna, R. (1); Malek, F. (1); Stanescu, C. (1); visa fler...; Horvat, S. (1); Castro, A. (1); Morel, M. (1); Ilic, MD (1); Pereira, A (1); Rodrigues, J. (1); Di Mauro, M. (1); Santos, R. (1); Rosano, G (1); Metra, M (1); Filippatos, G (1); Moura, B (1); Savarese, G (1); Bayes-Genis, A (1); Anker, SD (1); Seferovic, P (1); Lainscak, M (1); Lund, LH (1); Lima, G. (1); Ilic, S. (1); Confalonieri, M (1); Ferreira, C (1); Inciardi, RM (1); Frea, S (1); Sinagra, G (1); Leon, V (1); Pidello, S (1); Crespo-Leiro, MG (1); McDonagh, T (1); Piepoli, MF (1); Ruschitzka, F (1); Maggioni, AP (1); Ristic, AD (1); Afzelius, M. (1); Olsson, B (1); Aguiar, C (1); FERREIRA, A (1); Miceli, R (1); Coats, A (1); Reda, A (1); Araujo, I (1); Giordano, A (1); Silva, P (1); Petrovic, D. (1); visa färre...

Lärosäte: Karolinska Institutet (2)

Språk: Engelska (2)

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