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| 2. |
- Mårild, Karl, 1982, et al.
(författare)
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Association of Celiac Disease and Inflammatory Bowel Disease: A Nationwide Register-Based Cohort Study
- 2022
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Ingår i: The American journal of gastroenterology. - : Ovid Technologies (Wolters Kluwer Health). - 1572-0241 .- 0002-9270. ; 117:9, s. 1471-1481
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Tidskriftsartikel (refereegranskat)abstract
- INTRODUCTION: To determine the risk of inflammatory bowel disease (IBD) in patients with celiac disease (CeD) (and vice versa ) compared with general-population comparators. METHODS: Using Swedish histopathology and healthcare register data, we identified 48,551 patients with CeD and 83,529 with IBD diagnosed in 1969-2016. Each patient was compared with age- and sex-matched general-population comparators (CeD: n = 240,136; IBD: n = 408,195). Cox regression estimated hazard ratios (HRs) for IBD in patients with CeD and vice versa . Our main analyses were limited to events beyond the first year of follow-up to reduce potential surveillance bias. RESULTS: During follow-up, 784 (1.6%) patients with CeD were diagnosed with IBD compared with 1,015 (0.4%) matched comparators. In patients with CeD, the HR for IBD was 3.91 (95% confidence interval [CI] 3.56-4.31), with largely similar HRs for Crohn's disease (4.36; 3.72-5.11) and ulcerative colitis (3.40; 3.00-3.85). During follow-up, 644 (0.8%) patients with IBD and 597 (0.1%) comparators were diagnosed with CeD. The HR for CeD in patients with IBD was 5.49 (95% CI 4.90-6.16), with the highest risk estimates seen in ulcerative colitis (HR = 6.99; 6.07-8.05), and the HR for Crohn's disease was 3.31 (2.69-4.06). In patients with CeD and IBD, the diagnostic interval was usually <1 year; however, HRs of 3-4 were seen even after 10 years of follow-up. During 20 years of follow-up, 2.5% of patients with CeD developed incident IBD, and 1.3% of patients with IBD developed CeD. DISCUSSION: The bidirectional association between CeD diagnosis and IBD warrants attention in the initial assessment and follow-up of these conditions. Their co-occurrence, independent of temporal sequence, suggests shared etiology. Copyright © 2022 by The American College of Gastroenterology.
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- Castro Alves, Victor, 1986-, et al.
(författare)
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Aroma-Active Compounds of Capsicum Chinense Var. Biquinho
- 2014. - 1
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Ingår i: Flavour Science. - Salt Lake City : Academic Press. - 9780123985491 ; , s. 567-571
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Bokkapitel (refereegranskat)abstract
- Capsicum chinense var. Biquinho presents a strong aroma without the burning pepper sensation. Headspace volatile compounds were isolated by SPME and analyzed by GC-FID, GC-MS, and GC-O. The major compounds profile showed similarity to the profile of spicier peppers, but several minor compounds presented high importance to Biquinho’s characteristic flavor. Aromagram showed 72 compounds; where α-cardinol, heptylisopentanoate, p-xylene, isohexanol, hexyl butanoate, and (Z)-3-hexenyl pentanoate may be potential markers for the sweet and mild pepper flavor of Biquinho. In future, genetic materials of other chili peppers may have crosses with this pepper, which will improve their sensory characteristics.
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- Penha, Maria Flávia A., et al.
(författare)
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Varietal Differences in the Volatile Profile of Bananas with Resistance to Black Leaf Streak Disease
- 2014. - 1
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Ingår i: Flavour Science. - Salt Lake City : Academic Press. - 9780123985491 ; , s. 597-600
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Bokkapitel (refereegranskat)abstract
- In Brazil, black leaf streak disease, also known as black Sigatoka, is devastating to traditional banana cultivars. Government research institutes are developing new resistant varieties, but if the sensory properties are not taken into account, the breeding program may not succeed. The objective of this work was to compare, by principal component analysis (PCA), the volatile profile (GC-MS) of the most popular banana cultivars in Brazil (Prata and Pacovan), susceptible to black Sigatoka, with nine resistant hybrids. Results showed that Galil 18 and Pacovan Ken were similar to traditional cultivars. Japira presented the richest volatile profile. These cultivars have great potential to replace fruits that are susceptible to banana diseases.
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- Pinto, Náyra O.F., et al.
(författare)
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Volatile Profile of New Improved Brazilian Capsicum chinense Peppers
- 2014. - 1
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Ingår i: Flavour Science. - Salt Lake City : Academic Press. - 9780123985491 ; , s. 643-647
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Bokkapitel (refereegranskat)abstract
- Brazilian geneticists are developing aromatic peppers that, besides their burning sensation, can also add flavor to foods. In this work, the volatile profiles of two new genotypes, CNPH 3931 and CNPH 4080, were compared to the profile of Orange Biquinho pepper, a very scented but not pungent Brazilian variety. Headspace volatile compounds were isolated by SPME and identified by GC-MS. The new genotypes presented very similar volatile profiles, with fewer compounds but higher volatile quantity when compared to Biquinho. They lack some important compounds to Biquinho’s aroma, but the presence of other esters can add a variety of desirable notes. These CNPH peppers were shown to be promising materials.
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| 6. |
- Trindade, Inês, 1990, et al.
(författare)
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Behavioural response to illness: development and validation of a self-report measure of illness behaviour avoidance
- 2023
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Ingår i: Current Psychology. - : Springer Science and Business Media LLC. - 1046-1310 .- 1936-4733. ; 42:11, s. 9261-9269
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Tidskriftsartikel (refereegranskat)abstract
- A robust scale capable of assessing illness-related experiential avoidance (EA) in any given medical condition is currency lacking. Further, there is no available measure that assesses EA related to illness behaviours, i.e., actions and/or reactions in relation to feeling unwell that have the purpose of defining one's state of health and obtaining physical or emotional relief from perceived or actual illness. This study intends to fill this significant gap by presenting the development and psychometric test of a measure of EA related to illness behaviour, the Illness Behaviour Avoidance Scale (IBAS). A total of 370 Portuguese adults with chronic illness participated in the study. The structure and validity of the IBAS was tested through an Exploratory Factor Analysis (EFA; n = 185), a Confirmatory Factor Analysis (CFA; n = 185), and reliability analyses. The IBAS presented a 7-item unifactorial structure, with good global (CMIN/DF = 2.08; CFI = 0.97; TLI = 0.94; SRMR = 0.04; RMSEA = 0.08, p = 0.139) and local adjustments (SRWs 0.56-0.73; SMCs 0.31-0.53). It also presented a good internal consistency (with alpha s = 0.82), and construct and discriminant validity. The IBAS appears to be a significant improvement from the use of previous EA measures in illness contexts. This scale can provide a measurement of whether the behavioural response to any given condition is a manifestation of EA.
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