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Sökning: WFRF:(Rittner Ralf)

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  • Balidemaj, Festina, et al. (författare)
  • Prenatal Exposure to Locally Emitted Air Pollutants Is Associated with Birth Weight : An Administrative Cohort Study from Southern Sweden
  • 2022
  • Ingår i: Toxics. - : MDPI. - 2305-6304. ; 10:7
  • Tidskriftsartikel (refereegranskat)abstract
    • While prenatal exposure to ambient air pollution has been shown to be associated with reduced birth weight, there is substantial heterogeneity across studies, and few epidemiological studies have utilized source-specific exposure data. The aim of the present study was, therefore, to investigate the associations between local, source-specific exposure to fine particulate matter (PM2.5) during pregnancy and birth weight. An administrative cohort comprising 40,245 singleton births from 2000 to 2009 in Scania, Sweden, was combined with data on relevant covariates. Investigated sources of PM2.5 included all local sources together as well as tailpipe exhaust, vehicle wear-and-tear, and small-scale residential heating separately. The relationships between these exposures, rep-resented as interquartile range (IQR) increases, and birth weight (continuous) and low birth weight (LBW; <2500 g) were analyzed in crude and adjusted models. Each local PM2.5 source investigated was associated with reduced birth weight; average decreases varied by source (12–34 g). Only small-scale residential heating was clearly associated with LBW (adjusted odds ratio: 1.14 (95% confidence interval: 1.04–1.26) per IQR increase). These results add to existing evidence that prenatal exposure to ambient air pollution disrupts fetal growth and suggest that PM2.5 from both vehicles and small-scale residential heating may reduce birth weight.
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  • Björk, Jonas, et al. (författare)
  • Exploring inter-rater reliability and measurement properties of environmental ratings using kappa and colocation quotients
  • 2014
  • Ingår i: Environmental Health. - 1476-069X. ; 13
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: Available evidence suggest that perceptions or ratings of the neighborhood, e.g. as being green, walkable or noisy, are important for effects on health and wellbeing, also after controlling for objective measures of identical or similar features. When evaluating effects of the perceived environment, it is important that measurement properties and the reliability of the environmental ratings are evaluated before decisions about how these ratings should be handled in the statistical analyses are made. In this paper we broaden the usage of two association measures, the well-known kappa statistic and the novel colocation quotient (CLQ), to studies of inter-rater reliability and of associations between different categorical ratings in spatial contexts. Methods: We conducted reliability analysis of a survey instrument for assessing perceived greenness at geographical point locations, here the close outdoor environment within 5-10 minutes walking distance from home. Data were obtained from a public health survey conducted in 2008 in Scania, southern Sweden (n = 27 967 participants). Results: The results demonstrate the usefulness of kappa and CLQ as tools for assessing reliability and measurement properties of environmental rating scales when used at geographical point locations. We further show that the two measures are interchangeable, i.e. kappa can be accurately approximated from CLQ and vice versa, but can be used for somewhat different purposes in reliability analyses. Inter-rater reliability between the nearest neighbors was demonstrated for all five items of the evaluated instrument for assessing perceived greenness, albeit with clear differences across the items. Conclusion: Reliability analysis employing kappa and CLQ can be used as a basis for informed decisions about, for instance, how dichotomizations of the ratings should be defined and how missing or indefinite ratings should be handled. Such reliability analyses can thus serve as guidance for subsequent epidemiological studies of associations between environmental ratings, health and wellbeing.
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  • Bodin, Theo, et al. (författare)
  • Road traffic noise, air pollution and myocardial infarction: a prospective cohort study.
  • 2016
  • Ingår i: International Archives of Occupational and Environmental Health. - : Springer Science and Business Media LLC. - 1432-1246 .- 0340-0131. ; 89:5, s. 793-802
  • Tidskriftsartikel (refereegranskat)abstract
    • Both road traffic noise and air pollution have been linked to cardiovascular disease. However, there are few prospective epidemiological studies available where both road traffic noise and air pollution have been analyzed simultaneously. The aim of this study was to investigate the relation between road traffic noise, air pollution and incident myocardial infarction in both current (1-year average) and medium-term (3-year average) perspective.
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5.
  • Flanagan, Erin, et al. (författare)
  • Exposure to local, source-specific ambient air pollution during pregnancy and autism in children : a cohort study from southern Sweden
  • 2023
  • Ingår i: Scientific Reports. - : Springer Science and Business Media LLC. - 2045-2322. ; 13:1
  • Tidskriftsartikel (refereegranskat)abstract
    • Evidence of air pollution exposure, namely, ambient particulate matter (PM), during pregnancy and an increased risk of autism in children is growing; however, the unique PM sources that contribute to this association are currently unknown. The aim of the present study was to investigate local, source-specific ambient PM exposure during pregnancy and its associations with childhood autism, specifically, and autism spectrum disorders (ASD) as a group. A cohort of 40,245 singleton births from 2000 to 2009 in Scania, Sweden, was combined with data on locally emitted PM with an aerodynamic diameter < 2.5 µm (PM2.5). A flat, two-dimensional dispersion model was used to assess local PM2.5 concentrations (all-source PM2.5, small-scale residential heating- mainly wood burning, tailpipe exhaust, and vehicle wear-and-tear) at the mother’s residential address during pregnancy. Associations were analyzed using binary logistic regression. Exposure to local PM2.5 during pregnancy from each of the investigated sources was associated with childhood autism in the fully adjusted models. For ASD, similar, but less pronounced, associations were found. The results add to existing evidence that exposure to air pollution during pregnancy may be associated with an increased risk of childhood autism. Further, these findings suggest that locally produced emissions from both residential wood burning and road traffic-related sources (tailpipe exhaust and vehicle wear-and-tear) contribute to this association.
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6.
  • Hansson, Gert-Åke, et al. (författare)
  • Physical workload in various types of work: Part I. Wrist and forearm
  • 2009
  • Ingår i: International Journal of Industrial Ergonomics. - : Elsevier BV. - 0169-8141. ; 39:1, s. 221-233
  • Tidskriftsartikel (refereegranskat)abstract
    • The quantitative relationship between exposure to physical risk factors and upper extremity work-related musculoskeletal disorders (UE-WMSDs) is virtually unknown. To explore the variation, objective measurements were derived in 43 types of work (686 individuals), using goniometry for the wrists and electromyography (EMG) for the forearm extensor muscles. The variations due to work were great for wrist movements, wrist positions, muscular rest, as well as peak load, ranging 1.4-54 degrees/s (flexion velocity; 50th percentile), -30 degrees-3 degrees (flexion angle; 50th percentile), 0.2-23% of time, and 3.4-41% of maximal EMG (90th percentile), respectively. Even within work categories, e.g. "repetitive industrial", there were large variations for all measures. Hence, classification without measurements has limited value. All movement measures were highly correlated (vertical bar r(s)vertical bar=0.82-0.99), but only weakly so to positions (vertical bar r(s)vertical bar = 0.01-0.43). Muscular rest and "static load" (10th percentile), were highly correlated (r(s) = -0.92), but not associated to peak load (90th percentile; vertical bar r(s)vertical bar= 0.05 and 0.08, respectively). Most low-velocity work was accompanied by much muscular rest; however, the low velocity for mouse-intensive computer-work meant very little rest. Technical measurements are suitable as exposure measures in epidemiological studies, as well as a base for decisions about interventions. The multidimensional character of exposure - wrist movements, wrist postures, muscular recovery, and peak load - has to be considered. Relevance to industry: Direct measurements provide objective and quantitative measures of the main physical risk factors for UE-WMSDs, appropriate for estimating the risk, as well as giving priority to, and evaluating, interventions. (c) 2008 Elsevier B.V. All rights reserved.
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7.
  • Hansson, Gert-Åke, et al. (författare)
  • Physical workload in various types of work: Part II. Neck, shoulder and upper arm
  • 2010
  • Ingår i: International Journal of Industrial Ergonomics. - : Elsevier BV. - 0169-8141. ; 40:3, s. 267-281
  • Tidskriftsartikel (refereegranskat)abstract
    • To explore the correlation between, and the variation in, various measures of exposure to potential risk factors for work-related upper extremity musculoskeletal disorders (UE-WMSDs), physical workload was measured in 43 types of work (713 individuals), using inclinometry for the head and upper arms, and electromyography (EMG) for the trapezius muscles. Many exposure measures were highly correlated. Head flexion (90th percentile), extension (1st percentile), and movements (50th percentile); arm elevation (99th percentile) and movements (50th percentile); trapezius muscular rest (fraction of time) and peak load (90th percentile), constitute main exposure dimensions. The variations were large: head: flexion 9 degrees-63 degrees, extension -39 degrees-4 degrees, movements 2.3-33 degrees/s; arm: elevation 49 degrees-124 degrees, movements 3.0-103 degrees/s; trapezius: muscular rest 0.8%-52% of time, peak load 3.1%-24% of maximal EMC. Even within work categories, e.g. "repetitive industrial", there were large variations. Somewhat higher loads were recorded on the right as compared to the left side (differences: arm elevation 2, arm movements 19%; trapezius peak load 18%), but these were small compared to the differences due to work. There were high correlations between movements of arm and head (r(s) = 0.96), as well as arm and wrist (r(s) = 0.92), and between, on the one hand, trapezius muscular rest and peak load, and on the other, arm and head movements (vertical bar r(s)vertical bar = 0.47-0.62), as well as arm elevation (vertical bar r(s)vertical bar = 0.54-0.85), which has to be considered when assessing exposure-response relations. Relevance to industry: Direct measurements provide objective and quantitative data of the main physical risk factors for UE-WMSDs, appropriate for estimating the risk, as well as giving priority to and evaluating interventions. (C) 2009 Elsevier B.V. All rights reserved.
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