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Sökning: WFRF:(Roberts A.) > Högskolan Kristianstad

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1.
  • Zhang, X., et al. (författare)
  • Human total, basal and activity energy expenditures are independent of ambient environmental temperature
  • 2022
  • Ingår i: iScience. - : Elsevier Inc.. - 2589-0042. ; 25:8
  • Tidskriftsartikel (refereegranskat)abstract
    • Lower ambient temperature (Ta) requires greater energy expenditure to sustain body temperature. However, effects of Ta on human energetics may be buffered by environmental modification and behavioral compensation. We used the IAEA DLW database for adults in the USA (n = 3213) to determine the effect of Ta (−10 to +30°C) on TEE, basal (BEE) and activity energy expenditure (AEE) and physical activity level (PAL). There were no significant relationships (p > 0.05) between maximum, minimum and average Ta and TEE, BEE, AEE and PAL. After adjustment for fat-free mass, fat mass and age, statistically significant (p < 0.01) relationships between TEE, BEE and Ta emerged in females but the effect sizes were not biologically meaningful. Temperatures inside buildings are regulated at 18–25°C independent of latitude. Hence, adults in the US modify their environments to keep TEE constant across a wide range of external ambient temperatures.
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2.
  • Roberts, Frank A, et al. (författare)
  • Periodontitis vaccine decreases local prostaglandin E2 levels in a primate model.
  • 2004
  • Ingår i: Infection and Immunity. - 0019-9567 .- 1098-5522. ; 72:2, s. 1166-1168
  • Tidskriftsartikel (refereegranskat)abstract
    • Interleukin-1beta, tumor necrosis factor alpha, prostaglandin E2 (PGE2), and Porphyromonas gingivalis-specific immunoglobulin G levels in gingival crevicular fluid were measured in primates immunized with a P. gingivalis vaccine followed by ligature-induced periodontitis. Only PGE2 levels were dramatically suppressed (P < 0.0001) in immunized animals versus controls. A significant correlation (P < 0.027) was also found between PGE2 levels and decreased bone loss scores. This study presents the first evidence of a potential mechanism involved in periodontitis vaccine-induced suppression of bone loss in a nonhuman primate model and offers insight into the role of PGE2 in periodontal destruction.
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