| 1. |
- Lisacek, F., et al.
(författare)
-
Databases and associated tools for glycomics and glycoproteomics
- 2017
-
Ingår i: High-Throughput Glycomics and Glycoproteomics. Eds: Gordan Lauc & Manfred Wuhrer. - New York : Springer. - 1064-3745. - 9781493964932 - 9781493964918 ; , s. 235-264
-
Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- The access to biodatabases for glycomics and glycoproteomics has proven to be essential for current glycobiological research. This chapter presents available databases that are devoted to different aspects of glycobioinformatics. This includes oligosaccharide sequence databases, experimental databases, 3D structure databases (of both glycans and glycorelated proteins) and association of glycans with tissue, disease, and proteins. Specific search protocols are also provided using tools associated with experimental databases for converting primary glycoanalytical data to glycan structural information. In particular, researchers using glycoanalysis methods by U/HPLC (GlycoBase), MS (GlycoWorkbench, UniCarb-DB, GlycoDigest), and NMR (CASPER) will benefit from this chapter. In addition we also include information on how to utilize glycan structural information to query databases that associate glycans with proteins (UniCarbKB) and with interactions with pathogens (Sugar Bind). © Springer Science+Business Media New York 2017.
|
|
| 2. |
- Achcar, F., et al.
(författare)
-
The Silicon Trypanosome: A Test Case of Iterative Model Extension in Systems Biology
- 2014
-
Ingår i: Advances in Microbial Physiology. - : Elsevier. - 0065-2911. - 9780128001431 ; 64, s. 115-143
-
Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- The African trypanosome, Ttypanosoma brucei, is a unicellular parasite causing African Trypanosomiasis (sleeping sickness in humans and nagana in animals). Due to some of its unique properties, it has emerged as a popular model organism in systems biology. A predictive quantitative model of glycolysis in the bloodstream form of the parasite has been constructed and updated several times. The Silicon Trypanosome is a project that brings together modellers and experimentalists to improve and extend this core model with new pathways and additional levels of regulation. These new extensions and analyses use computational methods that explicitly take different levels of uncertainty into account. During this project, numerous tools and techniques have been developed for this purpose, which can now be used for a wide range of different studies in systems biology.
|
|
| 3. |
|
|
| 4. |
- Suárez-Rojas, Chaitanya, et al.
(författare)
-
Whale-watching tourism : future sustainability trends
- 2024
-
Ingår i: Routledge handbook of trends and issues in tourism sustainability, planning and development, management, and technology. - : Routledge. - 9781003291763 - 9781032271972 - 9781032271989 ; , s. 81-91
-
Bokkapitel (refereegranskat)abstract
- In whale-watching tourism, ensuring responsible human-cetacean interactions has raised critical academic debate over recent decades. This chapter reviews empirical evidence with the aim of progressing towards new trends that yield managerial responses for reconciling whale-watching tourism with sustainability principles. A co-word analysis of the last 30 years of scientific literature is conducted to explore the evolution of the leading topics, relate these to some industry milestones, and identify the research and managerial gaps. The evidence urges a new socio-ecological relationship approach in whale watching for sustainability, to be achieved by 2030 and beyond, by reorienting management practices to a more integrative approach based on scientific breakthroughs and collaborative stakeholder networks.
|
|
