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- Rylander, Christian, 1960
(författare)
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Historic review of long-term outcomes research
- 2019
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Ingår i: Current Opinion in Critical Care. - 1070-5295. ; 25:5, s. 523-529
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Forskningsöversikt (refereegranskat)abstract
- Purpose of reviewThis review summarizes the results from long-term intensive care outcome research over the past 50 years. Key findings from early studies are reflected in citations of contemporary research.Recent findingsThe postintensive care syndrome (PICS) is a multifaceted entity of residual disability and complications burdening survivors of critical illness. Some interventions applied early in the history of outcomes research have now been confirmed as effective in counteracting specific PICS components.SummaryInterest in patient-centred outcomes has been present since the beginning of modern intensive care. Findings from early long-term studies remain valid even in the face of contemporary large registries that facilitate follow-up of larger cohorts. A further understanding of the mechanisms leading to experienced physical and psychological impairment of PICS will be essential to the design of future intervention trials. © 2019 Wolters Kluwer Health, Inc. All rights reserved.
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- Rylander, Christian, 1960, et al.
(författare)
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Preoperative risk assessment in vascular surgery patients
- 1999
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Ingår i: Current Anaesthesia and Critical Care. ; 10, s. 179-185
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Forskningsöversikt (refereegranskat)abstract
- The patient scheduledf or peripheral vascular surgery is an increaseda naestheticc hallenge, mainly because of coexisting generalized cardiovascular atherosclerotic involvement leading to a high risk of perioperative cardiac complications. In clinical practice it is of importance preoperatively to predict, as accurately as possible, the potential risk of complications so that proper risk-reducing measures can be taken. Relevant clinical data, which have been included by Goldman and Detsky in multifactorial cardiac risk indices, are of potential value for differentiating between patients at low, intermediate, or high risk of perioperative cardiac morbidity and mortality. Patients with low risk scores can be accepted for surgery without further testing, thereby allowing more extensive cardiac testing, such as ambulatory ECG monitoring, exercise stresst esting, echocardiography,d ipyridamole thallium imaging, or coronary angiography,t o be reserved for patients with higher risk scores or overt cardiac problems. The risk stratification is of importance not only for decisions on preoperative prophylactic therapeutic measures (e.g. optimization of medical therapies, coronary artery revascularization), but also for decisions on intraoperative anaesthetic management and postoperative care
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