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| 2. |
- Björnsson, Bergthor, et al.
(författare)
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Digital twins to personalize medicine
- 2020
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Ingår i: Genome Medicine. - : Springer Science and Business Media LLC. - 1756-994X. ; 12:1
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Forskningsöversikt (refereegranskat)abstract
- Personalized medicine requires the integration and processing of vast amounts of data. Here, we propose a solution to this challenge that is based on constructing Digital Twins. These are high-resolution models of individual patients that are computationally treated with thousands of drugs to find the drug that is optimal for the patient.
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| 3. |
- Fritioff, Karin, et al.
(författare)
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Observation of an excited C2-4 ion
- 2004
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Ingår i: Journal of Physics B: Atomic, Molecular and Optical Physics. - : IOP Publishing. - 0953-4075 .- 1361-6455. ; 37:11, s. 2241-2246
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Tidskriftsartikel (refereegranskat)abstract
- This paper reports an experimental investigation of the electron impact detachment of C−4. We observe structure in the electron impact cross section for detaching a single electron from a C−4 cluster anion, which we attribute to the formation and decay of the C2−4 dianion. The system is energetically unstable and very rapidly decays via double autodetachment. The energy and width of the resonance were determined to be 8.8(5) eV and 1.4(5) eV, respectively, and the resonance lies 1.5(5) eV above the ground state of the neutral system. The experiment was conducted by merging monoenergetic electron and ion beams in the heavy ion storage ring CRYRING. The detachment channel was monitored by detecting neutral C4 fragments.
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| 4. |
- Fritioff, K, et al.
(författare)
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Single and double detachment from H-
- 2004
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Ingår i: Physical Review A. Atomic, Molecular, and Optical Physics. - 1050-2947 .- 1094-1622 .- 2469-9926 .- 2469-9934. ; 69:4, s. 042707-
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Tidskriftsartikel (refereegranskat)abstract
- Absolute cross sections for single and double detachment from H- following electron impact have been measured over a range of collision energies from the thresholds to 170 eV. The measurements were made using a magnetic storage ring. The ions in the ring were merged with a monoenergetic electron beam and neutral and positively charged fragments were detected. We cover larger energy ranges than in many of the previous experiments, and this is the first time both single and double detachment have been measured simultaneously. This allows us to present accurate ratios between the single and double detachment cross sections. On the basis of these ratio measurements we discuss possible mechanisms leading to double detachment.
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| 5. |
- Nitze, Florian, 1981, et al.
(författare)
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Direct support mixture painting, using Pd(0) organo-metallic compounds - an easy and environmentally sound approach to combine decoration and electrode preparation for fuel cells
- 2014
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Ingår i: Journal of Materials Chemistry A. - : Royal Society of Chemistry (RSC). - 2050-7488 .- 2050-7496. ; 2:48, s. 20973-20979
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Tidskriftsartikel (refereegranskat)abstract
- An inventive, fast and straight-forward approach for the direct preparation of fuel cell electrodes has been developed and tested. Our approach avoids long catalyst preparation and post-synthesis treatment. It reduces the use of chemicals and thereby concomitantly lowers the environmental impact and improves cost efficiency. It combines decoration of the support by palladium nanoparticles with electrode preparation through a simple one-step ink-painting and annealing process. Composites have been investigated by high resolution transmission electron microscopy, scanning electron microscopy, and Xray diffraction. Crystalline particles are well-attached and well-distributed on the support. Particles are of few nanometers in size and spherical for decorated Vulcan whereas they are larger and irregularly shaped for decorated helical carbon nanofibers (HCNFs). Electrodes with a metal loading of 0.8 mg cm(-2) have been tested in a direct formic acid fuel cell. Both the Vulcan and the HCNF electrodes show a similar and high power output of up to 120 mW mg(-1). They also show similar performances in deactivation experiments conducted at 200 mA cm(-2) even when using only high purity grade formic acid. After deactivation the electrodes show no structural damage, making them superior to most commercial catalysts. The electrodes can be completely regenerated to initial activity by simple treatment with water. The easy regeneration process indicates that CO-adsorption on the fuel cell anode catalyst is not the main poisoning mechanism responsible for electrode degeneration.
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| 6. |
- Sandström, Joakim, 1968, et al.
(författare)
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Laser photodetachment mass spectrometry
- 2004
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Ingår i: Nuclear Instruments and Methods in Physics Reseach B. - : Elsevier BV. - 0168-583X. ; 217:3, s. 513-520
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Tidskriftsartikel (refereegranskat)abstract
- We demonstrate that the technique of laser photodetachment spectroscopy on atomic negative ions can be used as a sensitivity enhancement tool in mass spectrometry, useful for suppressing both isotopic as well as molecular isobaric interferences. In the experiment a beam of negative ions and a laser beam are merged in a collinear geometry and the wavelength of the laser is tuned across the photodetachment threshold region. Due to the large differential Doppler shifts associated with the fast moving ions of different masses, it is possible to selectively detach ions of certain isotopes while leaving others unaffected. By choosing co-propagating laser and ion beams, the heavier isotopes of an element can be selectively detached, whereas counter propagating beams can be used to detach the lighter ones. In this paper we demonstrate the feasibility of the method in an experiment that was designed to selectively detach either 32S− or 34S− ions. The isotopic ratio of 34S/32S was enhanced by a factor of >50 over the natural value. This factor can be improved by using a laser that is better adapted to the measurement and by improving the vacuum conditions in order to further suppress the collisional background. The applicability of this technique to selectivity enhancement in measurements of the abundances of rare or ultra-rare isotopes is discussed.
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