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| 2. |
- Kim, Min Seo, et al.
(författare)
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Global burden of peripheral artery disease and its risk factors, 1990-2019 : a systematic analysis for the Global Burden of Disease Study 2019
- 2023
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Ingår i: The Lancet Global Health. - : Elsevier. - 2214-109X. ; 11:10, s. E1553-E1565
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Tidskriftsartikel (refereegranskat)abstract
- Background: Peripheral artery disease is a growing public health problem. We aimed to estimate the global disease burden of peripheral artery disease, its risk factors, and temporospatial trends to inform policy and public measures.Methods: Data on peripheral artery disease were modelled using the Global Burden of Disease, Injuries, and Risk Factors Study (GBD) 2019 database. Prevalence, disability-adjusted life years (DALYs), and mortality estimates of peripheral artery disease were extracted from GBD 2019. Total DALYs and age-standardised DALY rate of peripheral artery disease attributed to modifiable risk factors were also assessed.Findings: In 2019, the number of people aged 40 years and older with peripheral artery disease was 113 million (95% uncertainty interval [UI] 99 center dot 2-128 center dot 4), with a global prevalence of 1 center dot 52% (95% UI 1 center dot 33-1 center dot 72), of which 42 center dot 6% was in countries with low to middle Socio-demographic Index (SDI). The global prevalence of peripheral artery disease was higher in older people, (14 center dot 91% [12 center dot 41-17 center dot 87] in those aged 80-84 years), and was generally higher in females than in males. Globally, the total number of DALYs attributable to modifiable risk factors in 2019 accounted for 69 center dot 4% (64 center dot 2-74 center dot 3) of total peripheral artery disease DALYs. The prevalence of peripheral artery disease was highest in countries with high SDI and lowest in countries with low SDI, whereas DALY and mortality rates showed U-shaped curves, with the highest burden in the high and low SDI quintiles.Interpretation: The total number of people with peripheral artery disease has increased globally from 1990 to 2019. Despite the lower prevalence of peripheral artery disease in males and low-income countries, these groups showed similar DALY rates to females and higher-income countries, highlighting disproportionate burden in these groups. Modifiable risk factors were responsible for around 70% of the global peripheral artery disease burden. Public measures could mitigate the burden of peripheral artery disease by modifying risk factors.
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| 3. |
- Andrews, Jennifer E., et al.
(författare)
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SN 2017gmr : An Energetic Type II-P Supernova with Asymmetries
- 2019
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Ingår i: Astrophysical Journal. - : American Astronomical Society. - 0004-637X .- 1538-4357. ; 885:1
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Tidskriftsartikel (refereegranskat)abstract
- We present high-cadence UV, optical, and near-infrared data on the luminous Type II-P supernova SN;2017gmr from hours after discovery through the first 180 days. SN;2017gmr does not show signs of narrow, high-ionization emission lines in the early optical spectra, yet the optical light-curve evolution suggests that an extra energy source from circumstellar medium (CSM) interaction must be present for at least 2 days after explosion. Modeling of the early light curve indicates a ?500 R progenitor radius, consistent with a rather compact red supergiant, and late-time luminosities indicate that up to 0.130;;0.026 M of Ni-56 are present, if the light curve is solely powered by radioactive decay, although the Ni-56 mass may be lower if CSM interaction contributes to the post-plateau luminosity. Prominent multipeaked emission lines of H? and [O i] emerge after day 154, as a result of either an asymmetric explosion or asymmetries in the CSM. The lack of narrow lines within the first 2 days of explosion in the likely presence of CSM interaction may be an example of close, dense, asymmetric CSM that is quickly enveloped by the spherical supernova ejecta.
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| 4. |
- Gangopadhyay, Anjasha, et al.
(författare)
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Optical studies of two stripped-envelope supernovae – SN 2015ap (Type Ib) and SN 2016P (Type Ic)
- 2020
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Ingår i: Monthly notices of the Royal Astronomical Society. - : Oxford University Press (OUP). - 0035-8711 .- 1365-2966. ; 497:3, s. 3770-3789
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Tidskriftsartikel (refereegranskat)abstract
- We present the photometric and spectroscopic studies of a Type Ib SN 2015ap and a Type Ic SN 2016P. SN 2015ap is one of the bright (MV = −18.04 mag) Type Ib while SN 2016P lies at an average value among the Type Ic SNe (MV = −17.53 mag). Bolometric light-curve modelling of SNe 2015ap and 2016P indicates that both the SNe are powered by 56Ni + magnetar model with 56Ni masses of 0.01 and 0.002 M⊙, ejecta masses of 3.75 and 4.66 M⊙, spin period P0 of 25.8 and 36.5 ms, and magnetic field Bp of 28.39 × 1014 and 35.3 × 1014 G, respectively. The early spectra of SN 2015ap show prominent lines of He with a ‘W’ feature due to Fe complexes while other lines of Mg ii, Na i, and Si ii are present in both SNe 2015ap and 2016P. Nebular phase [O i] profile indicates an asymmetric profile in SN 2015ap. The [O i]/[Ca ii] ratio and nebular spectral modelling of SN 2015ap hint towards a progenitor mass between 12 and 20 M⊙.
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| 5. |
- Singh, Parminder, et al.
(författare)
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Dew-Cloud-Based Hierarchical Federated Learning for Intrusion Detection in IoMT
- 2023
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Ingår i: IEEE journal of biomedical and health informatics. - : IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC. - 2168-2194 .- 2168-2208. ; 27:2, s. 722-731
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Tidskriftsartikel (refereegranskat)abstract
- The coronavirus pandemic has overburdened medical institutions, forcing physicians to diagnose and treat their patients remotely. Moreover, COVID-19 has made humans more conscious about their health, resulting in the extensive purchase of IoT-enabled medical devices. The rapid boom in the market worth of the internet of medical things (IoMT) captured cyber attackers attention. Like health, medical data is also sensitive and worth a lot on the dark web. Despite the fact that the patients health details have not been protected appropriately, letting the trespassers exploit them. The system administrator is unable to fortify security measures due to the limited storage capacity and computation power of the resource-constrained network devices. Although various supervised and unsupervised machine learning algorithms have been developed to identify anomalies, the primary undertaking is to explore the swift progressing malicious attacks before they deteriorate the wellness systems integrity. In this paper, a Dew-Cloud based model is designed to enable hierarchical federated learning (HFL). The proposed Dew-Cloud model provides a higher level of data privacy with greater availability of IoMT critical application(s). The hierarchical long-term memory (HLSTM) model is deployed at distributed Dew servers with a backend supported by cloud computing. Data pre-processing feature helps the proposed model achieve high training accuracy (99.31%) with minimum training loss (0.034). The experiment results demonstrate that the proposed HFL-HLSTM model is superior to existing schemes in terms of performance metrics such as accuracy, precision, recall, and f-score.
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| 6. |
- Singh, Sanjay Kumar, et al.
(författare)
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A comparison between use of spray and freeze drying techniques for preparation of solid self-microemulsifying formulation of valsartan and in vitro and in vivo evaluation
- 2013
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Ingår i: BioMed Research International. - : Hindawi Limited. - 2314-6133 .- 2314-6141. ; 2013
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Tidskriftsartikel (refereegranskat)abstract
- The objective of the present study was to develop self micro emulsifying formulation (SMEF) of valsartan to improve its oral bioavailability. The formulations were screened on the basis of solubility, stability, emulsification efficiency, particle size and zeta potential. The optimized liquid SMEF contains valsartan (20% w/w), Capmul MCM C8 (16% w/w), Tween 80 (42.66% w/w) and PEG 400 (21.33% w/w) as drug, oil, surfactant and co-surfactant, respectively. Further, Liquid SMEF was adsorbed on Aerosol 200 by spray and freeze drying methods in the ratio of 2: 1 and transformed into free flowing powder. Both the optimized liquid and solid SMEF had the particle size <200 nm with rapid reconstitution properties. Both drying methods are equally capable for producing stable solid SMEF and immediate release of drug in in vitro and in vivo conditions. However, the solid SMEF produced by spray drying method showed high flowability and compressibility. The solid state characterization employing the FTIR, DSC and XRD studies indicated insignificant interaction of drug with lipid and adsorbed excipient. The relative bioavailability of solid SMEF was approximately 1.5 to 3.0 folds higher than marketed formulation and pure drug. Thus, the developed solid SMEF illustrates an alternative delivery of valsartan as compared to existing formulations with improved bioavailability
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| 7. |
- Ashish, K.C. 1982-, et al.
(författare)
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Coverage, associated factors, and impact of companionship during labor : A large-scale observational study in six hospitals in Nepal
- 2019
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Ingår i: Birth. - : John Wiley & Sons. - 0730-7659 .- 1523-536X. ; 47:1, s. 80-88
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: Companionship at the time of birth is a nonclinical intervention that has been proven to improve the quality of intrapartum care. This study aims to evaluate the coverage, associated factors, and impact of companionship during labor at public hospitals in Nepal.METHODS: We conducted a cross-sectional observational study in six public hospitals in Nepal. The study was conducted from July 2018 to August 2018. Data were collected on sociodemographic, maternal, obstetric, and neonatal characteristics from patient case notes and through predischarge interviews. Coverage of companionship during labor and its association with intrapartum care was analyzed. Bivariate and multivariate analyses were done to assess the association between companionship during labor and demographic, obstetric, and neonatal characteristics.RESULTS: A total of 63 077 women participated in the study with 19% of them having a companion during labor. Women aged 19-24 years had 65% higher odds of having a companion during labor compared with women aged 35 years and older (aOR 1.65 [95% CI, 1.40-1.94]). Women who were from an advantaged ethnic group (Chhetri/Brahmin) had fourfold higher odds of having a companion than women from a disadvantaged group (aOR 3.84; [95% CI, 3.24-4.52]). Women who had companions during labor had fewer unnecessary cesarean births than those who had no companions (5.2% vs 6.8%, P < .001).CONCLUSIONS: In Nepal, sociodemographic factors affect women's likelihood of having a companion during labor. As companionship during labor is associated with improved quality of care, health facilities should encourage women's access to birth companions.
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| 8. |
- Baranwal, Neha, 1988-, et al.
(författare)
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Extracting Primary Objects and Spatial Relations from Sentences
- 2019
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Konferensbidrag (refereegranskat)abstract
- In verbal human-robot interaction natural language utterances have to be grounded in visual scenes by the robot. Visual language grounding is a challenging task that includes identifying a primary object among several objects, together with the object properties and spatial relations among the objects. In this paper we focus on extracting this information from sentences only. We propose two language modelling techniques, one uses regular expressions and the other one utilizes Euclidian distance. We compare these two proposed techniques with two other techniques that utilize tree structures, namely an extended Hobb’s algorithm and an algorithm that utilizes a Stanford parse tree. A comparative analysis between all language modelling techniques shows that our proposed two approaches require less computational time than the tree-based approaches. All approaches perform good identifying the primary object and its property, but for spatial relation extraction the Stanford parse tree algorithm performs better than the other language modelling techniques. Time elapsed for the Stanford parse tree algorithm is higher than for the other techniques.
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| 9. |
- Baranwal, Neha, 1988-, et al.
(författare)
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Fusion of Gesture and Speech for Increased Accuracy in Human Robot Interaction
- 2019
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Ingår i: 2019 24th International Conference on Methods and Models in Automation and Robotics (MMAR). - : IEEE. - 9781728109336 ; , s. 139-144
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Konferensbidrag (refereegranskat)abstract
- An approach for decision-level fusion for gesture and speech based human-robot interaction (HRI) is proposed. A rule-based method is compared with several machine learning approaches. Gestures and speech signals are initially classified using hidden Markov models, reaching accuracies of 89.6% and 84% respectively. The rule-based approach reached 91.6% while SVM, which was the best of all evaluated machine learning algorithms, reached an accuracy of 98.2% on the test data. A complete framework is deployed in real time humanoid robot (NAO) which proves the efficacy of the system.
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| 10. |
- Bind, A. K., et al.
(författare)
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Influence of loading rate and hydrogen content on fracture toughness of Zr-2.5Nb pressure tube material
- 2015
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Ingår i: Journal of Nuclear Materials. - : Elsevier BV. - 0022-3115. ; 465, s. 177-188
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Tidskriftsartikel (refereegranskat)abstract
- For the safety assessment of PHWR, it is required to study the flaw tolerance capacity of the pressure tubes as a function of the loading rate. In this work, the effect of loading rate and hydrogen content on the fracture behaviour of a Zr-2.5Nb alloy pressure tube was investigated between 25 and 300 degrees C. For the as received material, the pulling rate only had an effect on fracture toughness at 25 degrees C whereas for. hydrided material the pulling rate affected fracture toughness in the transition regime. For all pulling rates, hydrided materials showed typical S curve behavior with an increase in lower shelf, upper shelf and transition temperature with pulling rate. The number of axial splits on fracture surfaces increased with an increase in the pulling rate and a decrease in temperature and fracture toughness was found to decrease with an increase in the number of axial splits. The reduction in fracture toughness is attributed to a localised deformation between axial splits. (C) 2015 Elsevier B.V. All rights reserved.
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