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Träfflista för sökning "WFRF:(Singhal Sandeep) "

Sökning: WFRF:(Singhal Sandeep)

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1.
  • Dadaev, Tokhir, et al. (författare)
  • Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants.
  • 2018
  • Ingår i: ; 9:1
  • Tidskriftsartikel (refereegranskat)abstract
    • Prostate cancer is a polygenic disease with a large heritable component. A number of common, low-penetrance prostate cancer risk loci have been identified through GWAS. Here we apply the Bayesian multivariate variable selection algorithm JAM to fine-map 84 prostate cancer susceptibility loci, using summary data from a large European ancestry meta-analysis. We observe evidence for multiple independent signals at 12 regions and 99 risk signals overall. Only 15 original GWAS tag SNPs remain among the catalogue of candidate variants identified; the remainder are replaced by more likely candidates. Biological annotation of our credible set of variants indicates significant enrichment within promoter and enhancer elements, and transcription factor-binding sites, including AR, ERG and FOXA1. In 40 regions at least one variant is colocalised with an eQTL in prostate cancer tissue. The refined set of candidate variants substantially increase the proportion of familial relative risk explained by these known susceptibility regions, which highlights the importance of fine-mapping studies and has implications for clinical risk profiling.
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3.
  • Chawla, Amit Kumar, et al. (författare)
  • Study of composition dependent structural, optical, and magnetic properties of Cu-doped Zn1-xCdxS nanoparticles
  • 2010
  • Ingår i: Journal of Applied Physics. - 0021-8979 .- 1089-7550. ; 108:12, s. 123519-
  • Tidskriftsartikel (refereegranskat)abstract
    • Cu-doped Zn1-xCdxS nanoparticles were synthesized by coprecipitation technique in ice bath at 280 K. The band gap energy of Zn1-xCdxS:Cu nanoparticles can be tuned to a lower energy by increasing the Cd content, indicating the formation of the alloyed nanoparticles. The alloy structure is further supported by the systematic shifting of characteristic x-ray diffraction peaks to lower angles with increase in Cd content. Systematic copper doping induces a red shift in the energy band gap of Zn0.9Cd0.1S:Cu nanoparticles with increase in copper concentration. Cu-doped Zn0.9Cd0.1S nanoparticles were found to have ferromagnetic nature at 5 K whereas undoped particles were found to be diamagnetic. Green luminescence further proves proper doping of Cu into the ZnCdS matrix. It is believed that the green luminescence originates from the recombination between the shallow donor level (sulfur vacancy) and the t(2) level of Cu2+. This method provides an inexpensive and simple procedure to produce ternary ZnCdS: Cu nanoparticles with tunable optical properties via changing Cd and/or Cu concentrations.
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4.
  • Devi, Chandni, et al. (författare)
  • Electrical transport properties of InAs nanowires synthesized by a solvothermal method
  • 2020
  • Ingår i: Nanotechnology. - Bristol : Institute of Physics Publishing (IOPP). - 0957-4484 .- 1361-6528. ; 31:23
  • Tidskriftsartikel (refereegranskat)abstract
    • Nanowires are widely considered to be key elements in future disruptive electronics and photonics. This paper presents the first detailed study of transport mechanisms in single-crystalline InAs nanowires synthesized by a cheap solvothermal wet chemical method. From detailed analyses of temperature-dependent current-voltage characteristics, it was observed that contacted nanowires operate in a linear transport regime at biases below a critical cross-over voltage. For larger biases, the transport changes to space-charge-limited conduction assisted by traps. The characteristic parameters such as free electron concentration, trap concentration and energy distribution, and electron mobility were all calculated. It was demonstrated that the nanowires have key electrical properties comparable to those of InAs nanowires grown by molecular beam epitaxy. Our results might pave the way for cheap disruptive low-dimensional electronics such as resistive switching devices. © 2020 IOP Publishing Ltd.
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5.
  • Singhal, Sonal, et al. (författare)
  • Photoluminescence measurements in the phase transition region of Zn1-x Cd (x) S films
  • 2010
  • Ingår i: Journal of nanoparticle research. - 1388-0764 .- 1572-896X. ; 12:4, s. 1415-1421
  • Tidskriftsartikel (refereegranskat)abstract
    • Thin films of Zn1-x Cd (x) S (0.1 a parts per thousand currency sign x a parts per thousand currency sign 0.5) were prepared by using pulsed laser ablation technique on corning glass substrates. Phase transition from cubic to hexagonal in Zn1-x Cd (x) S films is determined by X-ray diffraction analysis. We observed a lowering in the phase transition temperature with increase in the cadmium concentration. Transmission electron microscopy suggests the crystalline nature of thin films with average particle size of 15 nm. The grown Zn1-x Cd (x) S samples show the high peak intensity ratio of the near band edge emission to the defect center luminescence even at room temperature, which indicates the small concentration of complex defects in the samples. Photoluminescence measurement show stoichiometric dependence of the energy band gap and is found to have quadratic dependence on x.
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