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Träfflista för sökning "WFRF:(Sinusas Albert J) ;pers:(Ljungberg Michael)"

Sökning: WFRF:(Sinusas Albert J) > Ljungberg Michael

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1.
  • Fan, Peng, et al. (författare)
  • Scatter and crosstalk corrections for (99m)Tc/(123)I dual-radionuclide imaging using a CZT SPECT system with pinhole collimators.
  • 2015
  • Ingår i: Medical Physics. - : Wiley. - 0094-2405 .- 2473-4209. ; 42:12, s. 6895-6911
  • Tidskriftsartikel (refereegranskat)abstract
    • The energy spectrum for a cadmium zinc telluride (CZT) detector has a low energy tail due to incomplete charge collection and intercrystal scattering. Due to these solid-state detector effects, scatter would be overestimated if the conventional triple-energy window (TEW) method is used for scatter and crosstalk corrections in CZT-based imaging systems. The objective of this work is to develop a scatter and crosstalk correction method for (99m)Tc/(123)I dual-radionuclide imaging for a CZT-based dedicated cardiac SPECT system with pinhole collimators (GE Discovery NM 530c/570c).
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2.
  • Velo, Alexandre F., et al. (författare)
  • 99mTc/123I Dual-Radionuclide Correction for Self-Scatter, Down-Scatter, and Tailing Effect for a CZT SPECT With Varying Tracer Distributions
  • 2023
  • Ingår i: IEEE Transactions on Radiation and Plasma Medical Sciences. - 2469-7311. ; 7:8, s. 839-850
  • Tidskriftsartikel (refereegranskat)abstract
    • Single-photon emission computed tomography systems distinguish radionuclides by using multiple energy windows. For cadmium zinc telluride (CZT) detectors, the energy spectrum has a low-energy tail leading to additional crosstalk between the radionuclides. Previous work developed models to correct the scatter and crosstalk for CZT-based dedicated cardiac systems with similar 99mTc/123I tracer distributions. These models estimate the primary and scatter components by solving a set of equations employing the maximum-likelihood expectation–maximization approach. A penalty term is applied to ensure convergence. The present work estimates the penalty term for any 99mTc/123I activity level. An iterative approach incorporating Monte Carlo into the iterative image reconstruction loops was developed to estimate the penalty terms. We used SIMIND and extended cardiac-torso phantoms in this study. Distribution of tracers in the myocardial tissue and blood pool was varied to simulate a dynamic acquisition. Evaluations of the estimated and the real penalty terms were performed using simulations and large animal data. The myocardium to blood pool ratio was calculated using regions of interests in the myocardial tissue and the blood pool for quantitative analysis. All corrected images yielded a good agreement with the gold standard images. In conclusion, we developed a CZT crosstalk correction method for quantitative imaging of 99mTc/123I activity levels by dynamically estimating the penalty terms.
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