| 1. |
- Andersson, Sten, et al.
(författare)
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Aktiebolagslagen - En kommentar. Del 1-3, med supplement 9
- 2014
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Bok (övrigt vetenskapligt/konstnärligt)abstract
- Lagen kommenteras utförligt paragraf för paragraf. Den nya lagen innehåller både sakliga och redaktionella ändringa, bl.a. reglerna om bolagsbildning, som utformats för att bättre överensstämma med hur bolagsbildning i praktiken går till, nya bestämmelser för samtyckes- och förköpsförbehåll, ett särskilt system för fullmaktsinsamling samt en mer enhetlig utformning av bestämmelserna om olika slag av värdeöverföringar från bolaget.
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| 2. |
- Klauninger, R, et al.
(författare)
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Serologic follow-up of children born to mothers with Ro/SSA autoantibodies
- 2009
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Ingår i: Lupus. - : SAGE Publications. - 0961-2033 .- 1477-0962. ; 18:9, s. 792-798
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Tidskriftsartikel (refereegranskat)abstract
- Neonatal lupus erythematosus (NLE) develops in foetuses of mothers with Ro/SSA and La/SSB antibodies and may include foetal atrioventricular block and dermatologic manifestations. In this study, we investigated postnatal Ro and La IgG, IgA and IgM antibody levels up to 1 year of age in 32 children born to Ro/SSA positive mothers. Antibody levels were correlated with NLE manifestations, and the role of breast feeding in transfer of autoantibodies from mother to child was evaluated. Ro52, Ro60 and La IgG antibodies all transferred from the mothers to their foetus in utero and were present in the infant at birth as detected by enzyme-linked immunosorbent assay using recombinant antigens and a synthetic peptide. A significant decrease in Ro52, Ro60 and La IgG autoantibody levels of the infants was observed from birth to 4–5 weeks of age ( P < 0.05, P < 0.05 and P < 0.01). Ro- and La-specific IgA and IgM antibodies were detected in the serum from a subset of mothers. However, Ro- and La-specific IgA and IgM antibody levels were low or non-detectable in children raised both with and without breastfeeding. Furthermore, NLE skin lesions developed independently of breastfeeding. Our findings support a role for placental materno-foetal transfer of IgG autoantibodies in the pathogenesis of NLE and indicate that refraining from breastfeeding does not protect from NLE skin involvement.
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| 3. |
- Maguire, Casey A., et al.
(författare)
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Microvesicle-associated AAV Vector as a Novel Gene Delivery System
- 2012
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Ingår i: Molecular Therapy. - New York : Nature Publishing Group. - 1525-0016 .- 1525-0024. ; 20:5, s. 960-971
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Tidskriftsartikel (refereegranskat)abstract
- Adeno-associated virus (AAV) vectors have shown remarkable efficiency for gene delivery to cultured cells and in animal models of human disease. However, limitations to AAV vectored gene transfer exist after intravenous transfer, including off-target gene delivery (e.g., liver) and low transduction of target tissue. Here, we show that during production, a fraction of AAV vectors are associated with microvesicles/exosomes, termed vexosomes (vector-exosomes). AAV capsids associated with the surface and in the interior of microvesicles were visualized using electron microscopy. In cultured cells, vexosomes outperformed conventionally purified AAV vectors in transduction efficiency. We found that purified vexosomes were more resistant to a neutralizing anti-AAV antibody compared to conventionally purified AAV. Finally, we show that vexosomes bound to magnetic beads can be attracted to a magnetized area in cultured cells. Vexosomes represent a unique entity which offers a promising strategy to improve gene delivery.
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| 4. |
- Nilsson, Jonas, et al.
(författare)
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Prostate cancer-derived urine exosomes : a novel approach to biomarkers for prostate cancer.
- 2009
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Ingår i: British journal of cancer. - : Springer Science and Business Media LLC. - 1532-1827 .- 0007-0920. ; 100:10, s. 1603-1607
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Tidskriftsartikel (refereegranskat)abstract
- Herein, we describe a novel approach in the search for prostate cancer biomarkers, which relies on the transcriptome within tumour exosomes. As a proof-of-concept, we show the presence of two known prostate cancer biomarkers, PCA-3 and TMPRSS2:ERG the in exosomes isolated from urine of patients, showing the potential for diagnosis and monitoring cancer patients status.
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| 5. |
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| 6. |
- Schuch, Reinhold, et al.
(författare)
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The new Stockholm Electron Beam Ion Trap (S-EBIT)
- 2010
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Ingår i: Journal of Instrumentation. - 1748-0221. ; 5, s. C12018-
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Tidskriftsartikel (refereegranskat)abstract
- A new laboratory for highly charged ions is being built up at Stockholm University. A fully refrigerated electron beam ion trap (R-EBIT, 3 T magnet, 30 keV electron energy) was installed. It was used for spectroscopic studies, ion cooling experiments, electron ion collisions, and highly-charged ion surface studies. Here we report on an upgrade of this EBIT to a ``Super EBIT'' (S-EBIT, 4 T magnet, 260 keV electron energy). The high-voltage trapping system, the ion injection as well as the extraction scheme of S-EBIT and the LabView based operational system of S-EBIT are described.
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| 7. |
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| 8. |
- Skog, Isaac, 1981-, et al.
(författare)
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Position and orientation estimation of a permanent magnet using a small-scale sensor array
- 2018
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Ingår i: I2MTC 2018 - 2018 IEEE International Instrumentation and Measurement Technology Conference. - : Institute of Electrical and Electronics Engineers Inc.. ; , s. 1-5
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Konferensbidrag (refereegranskat)abstract
- A maximum likelihood estimator for the determination of the position and orientation of a permanent magnet using an array of magnetometers is presented. To reduce the complexity and increase the robustness of the estimator, the likelihood function is concentrated and an iterative solution method for the resulting low-dimensional optimization problem is presented. The performance of the estimator is experimentally evaluated with a miniaturized sensor array that consists of 32 magnetometer triads. The results are compared to the Cramér-Rao bound for the estimation problem at hand. The comparisons show that the performance of the estimator is close to the Cramer-Rao bound; hence, the estimator is close to optimal. Further, the results illustrate that even with a matchbox-sized array and a small magnet with a dipole moment that has a magnitude of 7 2 · 10-3 Am2 the position and orientation of the magnet can, within a 80×80×80 mm volume, be estimated with a root mean square error of less than 10 mm and 15 deg, respectively.
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| 9. |
- Skog, Rolf, 1954, et al.
(författare)
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Aktiebolagslagen, del I-III inkl suppl 7
- 2012
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Bok (övrigt vetenskapligt/konstnärligt)abstract
- Ny reviderad upplaga. Lagen kommenteras utförligt paragraf för paragraf och nu har verket uppdaterats med ett supplement 7.
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| 10. |
- Sten, Andersson, et al.
(författare)
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Aktiebolagslagen, del I-III : inkl suppl 6
- 2011
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Bok (övrigt vetenskapligt/konstnärligt)abstract
- Ny reviderad upplaga. Lagen kommenteras utförligt paragraf för paragraf och nu har verket uppdaterats med ett Supplement 6. I arbetet har författningsförändringar intill SFS 2010:1516 kunnat beaktas. Även ny rättspraxis och nyutkommen litteratur har beaktats.
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