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1.	Lim, Stephen S, et al. (author) A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. 2012 In: Lancet. - 1474-547X. ; 380:9859, s. 2224-60 Journal article (peer-reviewed)abstract Quantification of the disease burden caused by different risks informs prevention by providing an account of health loss different to that provided by a disease-by-disease analysis. No complete revision of global disease burden caused by risk factors has been done since a comparative risk assessment in 2000, and no previous analysis has assessed changes in burden attributable to risk factors over time.
2.	Ludvigsson, Jonas F., 1969-, et al. (author) Outcome measures in coeliac disease trials : the Tampere recommendations 2018 In: Gut. - : BMJ Publishing Group Ltd. - 0017-5749 .- 1468-3288. ; 67:8, s. 1410-1424 Journal article (peer-reviewed)abstract Objective: A gluten-free diet is the only treatment option of coeliac disease, but recently an increasing number of trials have begun to explore alternative treatment strategies. We aimed to review the literature on coeliac disease therapeutic trials and issue recommendations for outcome measures.Design: Based on a literature review of 10 062 references, we (17 researchers and 2 patient representatives from 10 countries) reviewed the use and suitability of both clinical and non-clinical outcome measures. We then made expert-based recommendations for use of these outcomes in coeliac disease trials and identified areas where research is needed. Results: We comment on the use of histology, serology, clinical outcome assessment (including patient-reported outcomes), quality of life and immunological tools including gluten immunogenic peptides for trials in coeliac disease.Conclusion: Careful evaluation and reporting of outcome measures will increase transparency and comparability of coeliac disease therapeutic trials, and will benefit patients, healthcare and the pharmaceutical industry.

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Type of publication: journal article (2)

Type of content: peer-reviewed (2)

Author/Editor: Romieu, Isabelle (1); Petzold, Max, 1973 (1); Brunekreef, Bert (1); Sapkota, Amir (1); Farzadfar, Farshad (1); Jonas, Jost B. (1); show more...; Khang, Young-Ho (1); Lopez, Alan D. (1); Lozano, Rafael (1); Malekzadeh, Reza (1); Micha, Renata (1); Mozaffarian, Dariush (1); Naghavi, Mohsen (1); Vos, Theo (1); Murray, Christopher ... (1); Lim, Stephen S. (1); Mensah, George A. (1); Salomon, Joshua A. (1); Kurppa, Kalle (1); Gakidou, Emmanuela (1); Ludvigsson, Jonas F. ... (1); Woolf, Anthony D (1); Giovannucci, Edward (1); Room, Robin (1); Gmel, Gerhard (1); Walker, Marjorie M. (1); Li, Yang (1); Lan, Qing (1); Bell, Michelle L (1); Kan, Haidong (1); Cohen, Aaron (1); Roy, Ananya (1); Smith, Kirk R. (1); Graham, Kathryn (1); Anderson, H Ross (1); Shibuya, Kenji (1); Neal, Bruce (1); Laden, Francine (1); Pearce, Neil (1); Buchbinder, Rachelle (1); Borges, Guilherme (1); Ritz, Beate (1); Danaei, Goodarz (1); Lu, Yuan (1); Ezzati, Majid (1); Amann, Markus (1); Murray, Joseph A. (1); Smith, Emma (1); Kanis, John A (1); Straif, Kurt (1); show less...

University: University of Gothenburg (1); Örebro University (1); Karolinska Institutet (1)

Language: English (2)

Research subject (UKÄ/SCB): Medical and Health Sciences (2)

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