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Search: WFRF:(Strauss John) > Uppsala University

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1.	Jones, Gregory T., et al. (author) Meta-Analysis of Genome-Wide Association Studies for Abdominal Aortic Aneurysm Identifies Four New Disease-Specific Risk Loci 2017 In: Circulation Research. - 0009-7330 .- 1524-4571. ; 120:2, s. 341- Journal article (peer-reviewed)abstract Rationale: Abdominal aortic aneurysm (AAA) is a complex disease with both genetic and environmental risk factors. Together, 6 previously identified risk loci only explain a small proportion of the heritability of AAA. Objective: To identify additional AAA risk loci using data from all available genome-wide association studies. Methods and Results: Through a meta-analysis of 6 genome-wide association study data sets and a validation study totaling 10 204 cases and 107 766 controls, we identified 4 new AAA risk loci: 1q32.3 (SMYD2), 13q12.11 (LINC00540), 20q13.12 (near PCIF1/MMP9/ZNF335), and 21q22.2 (ERG). In various database searches, we observed no new associations between the lead AAA single nucleotide polymorphisms and coronary artery disease, blood pressure, lipids, or diabetes mellitus. Network analyses identified ERG, IL6R, and LDLR as modifiers of MMP9, with a direct interaction between ERG and MMP9. Conclusions: The 4 new risk loci for AAA seem to be specific for AAA compared with other cardiovascular diseases and related traits suggesting that traditional cardiovascular risk factor management may only have limited value in preventing the progression of aneurysmal disease.
2.	Abazov, V. M., et al. (author) Search for first generation leptoquark pair production in the electron plus missing energy plus jets final state 2011 In: Physical Review D. - 1550-7998 .- 1550-2368. ; 84:7, s. 071104- Journal article (peer-reviewed)abstract We present a search for the pair production of first generation scalar leptoquarks (LQ) in data corresponding to an integrated luminosity of 5.4 fb(-1) collected with the D0 detector at the Fermilab Tevatron Collider in p (p) over bar collisions at root s = 1.96 TeV. In the channel LQLQ -> eqv(e)q', where q, q' are u or d quarks, no significant excess of data over background is observed, and we set a 95% C. L. lower limit of 326 GeV on the LQ mass, assuming equal probabilities of LQ decays to eq and v(e)q'.
3.	Bombarda, F., et al. (author) Runaway electron beam control 2019 In: Plasma Physics and Controlled Fusion. - : IOP Publishing. - 1361-6587 .- 0741-3335. ; 61:1 Journal article (peer-reviewed)
4.	2018 In: Nuclear Fusion. - : IOP Publishing. - 1741-4326 .- 0029-5515. ; 58:1 Research review (peer-reviewed)

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Type of publication: journal article (3); research review (1)

Type of content: peer-reviewed (4)

Author/Editor: Price, D. (3); Jones, G. (2); Li, L. (2); Liu, Y. (2); Nowak, S. (2); Spagnolo, S. (2); show more...; Walker, R. (2); Yao, L. (2); Young, C. (2); Gao, Y. (2); Urban, J. (2); Buchanan, J. (2); Santos, J. (2); Thomas, P. (2); Kaufman, M (2); Taylor, D (2); Baker, A. (2); Clark, M. (2); Martin, A. (2); Robinson, S. (2); Gallagher, J. (2); Madsen, J. (2); Day, C. (2); Page, A. (2); Zhang, W. (2); West, A. (2); Smith, P. (2); Morris, J. (2); Lee, S (2); Williams, J (2); Wood, R (2); Williams, M (2); Bowden, M. (2); Davis, W. (2); Olsen, J. (2); Pereira, A (2); Afzal, M (2); Young, R. (2); Rodrigues, P (2); Silva, C. (2); Rodriguez, J. (2); Duran, I (2); Mayer, M. (2); Sinha, A. (2); Kundu, A. (2); Abreu, P. (2); Lopez, J. M. (2); Thomas, J. (2); Martin, Y. (2); Hjalmarsson, A. (2); show less...

University: Uppsala University (4)Undo refine; Royal Institute of Technology (2); Chalmers University of Technology (2); Stockholm University (1); Karolinska Institutet (1)

Language: English (4)

Research subject (UKÄ/SCB): Natural sciences (3); Medical and Health Sciences (1)

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