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Träfflista för sökning "WFRF:(Svensson J.) ;pers:(Svensson O)"

Search: WFRF:(Svensson J.) > Svensson O

  • Result 1-10 of 36
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  • Wuttke, Matthias, et al. (author)
  • A catalog of genetic loci associated with kidney function from analyses of a million individuals
  • 2019
  • In: Nature Genetics. - : NATURE PUBLISHING GROUP. - 1061-4036 .- 1546-1718. ; 51:6, s. 957-972
  • Journal article (peer-reviewed)abstract
    • Chronic kidney disease (CKD) is responsible for a public health burden with multi-systemic complications. Through transancestry meta-analysis of genome-wide association studies of estimated glomerular filtration rate (eGFR) and independent replication (n = 1,046,070), we identified 264 associated loci (166 new). Of these,147 were likely to be relevant for kidney function on the basis of associations with the alternative kidney function marker blood urea nitrogen (n = 416,178). Pathway and enrichment analyses, including mouse models with renal phenotypes, support the kidney as the main target organ. A genetic risk score for lower eGFR was associated with clinically diagnosed CKD in 452,264 independent individuals. Colocalization analyses of associations with eGFR among 783,978 European-ancestry individuals and gene expression across 46 human tissues, including tubulo-interstitial and glomerular kidney compartments, identified 17 genes differentially expressed in kidney. Fine-mapping highlighted missense driver variants in 11 genes and kidney-specific regulatory variants. These results provide a comprehensive priority list of molecular targets for translational research.
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  • Mauri, G., et al. (author)
  • The Multi-Blade Boron-10-based neutron detector performance using a focusing reflectometer
  • 2020
  • In: Journal of Instrumentation. - : IOP PUBLISHING LTD. - 1748-0221. ; 15:3
  • Journal article (peer-reviewed)abstract
    • The Multi-Blade is a Boron-10-based neutron detector designed for neutron reflectometers and developed for the two instruments (Estia and FREIA) planned for the European Spallation Source in Sweden. A demonstrator has been installed at the AMOR reflectometer at the Paul Scherrer Institut (PSI - Switzerland). AMOR exploits the Selene guide concept and can be considered a scaled-down demonstrator of Estia. The results of these tests are discussed. It will be shown how the characteristics of the Multi-Blade detector are features that allow the focusing reflectometry operation mode. Additionally the performance of the Multi-Blade, in terms of rate capability, exceeds current state-of-the-art technology. The improvements with respect to the previous prototypes are also highlighted; from background considerations to the linear and angular uniformity response of the detector.
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  • Result 1-10 of 36
Type of publication
journal article (32)
reports (3)
other publication (1)
Type of content
peer-reviewed (28)
other academic/artistic (8)
Author/Editor
Svensson, O (23)Undo refine
Raymond, C (4)
Gunnarsson, J (4)
Ahlberg, G (4)
Ponzer, S (4)
Tidermark, J (4)
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Nilsson, O (3)
Ryden, S (3)
Wallentin, L (3)
Swahn, E (3)
Holmberg, B (3)
Perk, J. (3)
Agrenius, Stefan, 19 ... (3)
Albertsson, J (3)
Tornkvist, H (3)
Hedman, A (3)
Lindahl, B (3)
Gustafsson, G. (3)
Lofmark, R (3)
Friden, J. (3)
Nicol, P (3)
Hulting, J (3)
Nilsson, J. (2)
Holm, T (2)
Larsson, O (2)
Larsson, L (2)
Karlsson, E (2)
Svensson, Lars E. O. (2)
Andersson, I (2)
Boman, K. (2)
Lundin, P (2)
Bastani, H (2)
Svensson, E. (2)
Samad, B (2)
Ohlsson, J (2)
Rehnqvist, N (2)
Lundin, L (2)
LUNDSTROM, T (2)
Andren, B (2)
Aronson, D. (2)
Sundqvist, C. (2)
Ekholm, J (2)
Nielsen, N. (2)
Nilsson, T.K. (2)
Svensson, P. O. (2)
Venge, P (2)
Thygesen, K (2)
Wilhelmsen, L (2)
THORSEN, S (2)
Lindstrom, G. (2)
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University
Karolinska Institutet (15)
Uppsala University (5)
Lund University (4)
University of Gothenburg (3)
Mid Sweden University (3)
Umeå University (2)
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Stockholm University (2)
Royal Institute of Technology (1)
Linköping University (1)
Jönköping University (1)
Swedish Environmental Protection Agency (1)
Linnaeus University (1)
RISE (1)
Högskolan Dalarna (1)
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Language
English (32)
Swedish (4)
Research subject (UKÄ/SCB)
Natural sciences (5)
Medical and Health Sciences (5)
Engineering and Technology (2)
Social Sciences (2)

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