| 1. |
- Niemi, MEK, et al.
(författare)
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- 2021
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swepub:Mat__t
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| 2. |
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| 3. |
- Yusuf, D, et al.
(författare)
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The transcription factor encyclopedia
- 2012
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Ingår i: Genome biology. - : Springer Science and Business Media LLC. - 1474-760X .- 1465-6906. ; 13:3, s. R24-
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Tidskriftsartikel (refereegranskat)
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| 4. |
- Anderson, J. P., et al.
(författare)
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A nearby super-luminous supernova with a long pre-maximum plateau and strong C (II) features
- 2018
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Ingår i: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 620
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Tidskriftsartikel (refereegranskat)abstract
- Context. Super-luminous supernovae (SLSNe) are rare events defined as being significantly more luminous than normal terminal stellar explosions. The source of the additional power needed to achieve such luminosities is still unclear. Discoveries in the local Universe (i.e. z < 0.1) are scarce, but afford dense multi-wavelength observations. Additional low-redshift objects are therefore extremely valuable.Aims. We present early-time observations of the type I SLSN ASASSN-18km/SN 2018bsz. These data are used to characterise the event and compare to literature SLSNe and spectral models. Host galaxy properties are also analysed.Methods. Optical and near-IR photometry and spectroscopy were analysed. Early-time ATLAS photometry was used to constrain the rising light curve. We identified a number of spectral features in optical-wavelength spectra and track their time evolution. Finally, we used archival host galaxy photometry together with H( II )region spectra to constrain the host environment.Results. ASASSN-18km/SN 2018bsz is found to be a type I SLSN in a galaxy at a redshift of 0.0267 (111 Mpc), making it the lowest-redshift event discovered to date. Strong C- II lines are identified in the spectra. Spectral models produced by exploding a Wolf-Rayet progenitor and injecting a magnetar power source are shown to be qualitatively similar to ASASSN-18km/SN 2018bsz, contrary to most SLSNe-I that display weak or non-existent C (II) lines. ASASSN-18km/SN 2018bsz displays along, slowly rising, red plateau of >26 days, before a steeper, faster rise to maximum. The host has an absolute magnitude of -19.8 mag (r), a mass of M-* = 1.5(-0.33)(+0.08) x 10(9) M-circle dot, and a star formation rate of =0.50(-0.19)(+2.22) M-circle dot yr(-1). A nearby H (II) region has an oxygen abundance (O3N2) of 8.31 +/- 0.01 dex.
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| 5. |
- Kurzawa-Akanbi, M., et al.
(författare)
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Retinal pigment epithelium extracellular vesicles are potent inducers of age-related macular degeneration disease phenotype in the outer retina
- 2022
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Ingår i: Journal of Extracellular Vesicles. - : Wiley. - 2001-3078. ; 11:12
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Tidskriftsartikel (refereegranskat)abstract
- Age-related macular degeneration (AMD) is a leading cause of blindness. Vision loss is caused by the retinal pigment epithelium (RPE) and photoreceptors atrophy and/or retinal and choroidal angiogenesis. Here we use AMD patient-specific RPE cells with the Complement Factor H Y402H high-risk polymorphism to perform a comprehensive analysis of extracellular vesicles (EVs), their cargo and role in disease pathology. We show that AMD RPE is characterised by enhanced polarised EV secretion. Multi-omics analyses demonstrate that AMD RPE EVs carry RNA, proteins and lipids, which mediate key AMD features including oxidative stress, cytoskeletal dysfunction, angiogenesis and drusen accumulation. Moreover, AMD RPE EVs induce amyloid fibril formation, revealing their role in drusen formation. We demonstrate that exposure of control RPE to AMD RPE apical EVs leads to the acquisition of AMD features such as stress vacuoles, cytoskeletal destabilization and abnormalities in the morphology of the nucleus. Retinal organoid treatment with apical AMD RPE EVs leads to disrupted neuroepithelium and the appearance of cytoprotective alpha B crystallin immunopositive cells, with some co-expressing retinal progenitor cell markers Pax6/Vsx2, suggesting injury-induced regenerative pathways activation. These findings indicate that AMD RPE EVs are potent inducers of AMD phenotype in the neighbouring RPE and retinal cells.
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| 6. |
- Yan, Lin, et al.
(författare)
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Helium-rich Superluminous Supernovae from the Zwicky Transient Facility
- 2020
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Ingår i: Astrophysical Journal Letters. - : American Astronomical Society. - 2041-8205 .- 2041-8213. ; 902:1
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Tidskriftsartikel (refereegranskat)abstract
- Helium is expected to be present in the massive ejecta of some hydrogen-poor superluminous supernovae (SLSN-I). However, until now only one event has been identified with He features in its photospheric spectra (PTF10hgi). We present the discovery of a new He-rich SLSN-I, ZTF19aawfbtg (SN2019hge), atz = 0.0866. This event has more than 10 optical spectra at phases from -41 to +103 days relative to the peak, most of which match well with that of PTF10hgi. Confirmation comes from a near-IR spectrum taken at +34 days, revealing Heifeatures with P-Cygni profiles at 1.083 and 2.058 mu m. Using the optical spectra of PTF10hgi and SN2019hge as templates, we examined 70 other SLSNe-I discovered by Zwicky Transient Facility in the first two years of operation and found five additional SLSNe-I with distinct He-features. The excitation of Heiatoms in normal core-collapse supernovae requires nonthermal radiation, as proposed by previous studies. These He-rich events cannot be explained by the traditional(56)Ni mixing model because of their blue spectra, high peak luminosities, and long rise timescales. Magnetar models offer a possible solution since pulsar winds naturally generate high-energy particles, potential sources of nonthermal excitation. An alternative model is the interaction between the ejecta and dense H-poor circumstellar material, which may be supported by observed undulations in the light curves. These six SLSNe-Ib have relatively low-peak luminosities (rest frameM(g) = -20.06 0.16).
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| 7. |
- Fremling, C., et al.
(författare)
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The Zwicky Transient Facility Bright Transient Survey. I. Spectroscopic Classification and the Redshift Completeness of Local Galaxy Catalogs
- 2020
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Ingår i: Astrophysical Journal. - : American Astronomical Society. - 0004-637X .- 1538-4357. ; 895:1
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Tidskriftsartikel (refereegranskat)abstract
- The Zwicky Transient Facility (ZTF) is performing a three-day cadence survey of the visible northern sky (similar to 3 pi) with newly found transient candidates announced via public alerts. The ZTF Bright Transient Survey (BTS) is a large spectroscopic campaign to complement the photometric survey. BTS endeavors to spectroscopically classify all extragalactic transients with m(peak) <= 18.5 mag in either the g(ZTF) or r(ZTF) filters, and publicly announce said classifications. BTS discoveries are predominantly supernovae (SNe), making this the largest flux-limited SN survey to date. Here we present a catalog of 761 SNe, classified during the first nine months of ZTF (2018 April 1-2018 December 31). We report BTS SN redshifts from SN template matching and spectroscopic host-galaxy redshifts when available. We analyze the redshift completeness of local galaxy catalogs, the redshift completeness fraction (RCF; the ratio of SN host galaxies with known spectroscopic redshift prior to SN discovery to the total number of SN hosts). Of the 512 host galaxies with SNe Ia, 227 had previously known spectroscopic redshifts, yielding an RCF estimate of 44% 4%. The RCF decreases with increasing distance and decreasing galaxy luminosity (for z < 0.05, or similar to 200 Mpc, RCF 0.6). Prospects for dramatically increasing the RCF are limited to new multifiber spectroscopic instruments or wide-field narrowband surveys. Existing galaxy redshift catalogs are only similar to 50% complete at r 16.9 mag. Pushing this limit several magnitudes deeper will pay huge dividends when searching for electromagnetic counterparts to gravitational wave events or sources of ultra-high-energy cosmic rays or neutrinos.
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| 8. |
- Lunnan, Ragnhild, et al.
(författare)
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Four (Super)luminous Supernovae from the First Months of the ZTF Survey
- 2020
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Ingår i: Astrophysical Journal. - : American Astronomical Society. - 0004-637X .- 1538-4357. ; 901:1
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Tidskriftsartikel (refereegranskat)abstract
- We present photometry and spectroscopy of four hydrogen-poor luminous supernovae discovered during the 2-month long science commissioning and early operations of the Zwicky Transient Facility (ZTF) survey. Three of these objects, SN 2018bym (ZTF18aapgrxo), SN 2018avk (ZTF18aaisyyp), and SN 2018bgv (ZTF18aavrmcg), resemble typical SLSN-I spectroscopically, while SN 2018don (ZTF18aajqcue) may be an object similar to SN 2007bi experiencing considerable host galaxy reddening, or an intrinsically long-lived, luminous, and red SN Ic. We analyze the light curves, spectra, and host galaxy properties of these four objects and put them in context of the population of SLSN-I. SN 2018bgv stands out as the fastest-rising SLSN-I observed to date, with a rest-frame g-band rise time of just 10 days from explosion to peak—if it is powered by magnetar spin-down, the implied ejecta mass is only 1 M ⊙. SN 2018don also displays unusual properties—in addition to its red colors and comparatively massive host galaxy, the light curve undergoes some of the strongest light-curve undulations postpeak seen in an SLSN-I, which we speculate may be due to interaction with circumstellar material. We discuss the promises and challenges of finding SLSNe in large-scale surveys like ZTF given the observed diversity in the population.
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| 9. |
- Petrushevska, T., et al.
(författare)
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The rise and fall of the iron-strong nuclear transient PS16dtm
- 2023
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Ingår i: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 669
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Tidskriftsartikel (refereegranskat)abstract
- Context. Thanks to the advent of large-scale optical surveys, a diverse set of flares from the nuclear regions of galaxies has recently been discovered. These include the disruption of stars by supermassive black holes at the centers of galaxies – nuclear transients known as tidal disruption events (TDEs). Active galactic nuclei (AGN) can show extreme changes in the brightness and emission line intensities, often referred to as changing-look AGN (CLAGN). Given the physical and observational similarities, the interpretation and distinction of nuclear transients as CLAGN or TDEs remains difficult. One of the obstacles of making progress in the field is the lack of well-sampled data of long-lived nuclear outbursts in AGN.Aims. Here, we study PS16dtm, a nuclear transient in a Narrow Line Seyfert 1 (NLSy1) galaxy, which has been proposed to be a TDE candidate. Our aim is to study the spectroscopic and photometric properties of PS16dtm, in order to better understand the outbursts originating in NLSy1 galaxies.Methods. Our extensive multiwavelength follow-up that spans around 2000 days includes photometry and spectroscopy in the UV/optical, as well as mid-infrared (MIR) and X-ray observations. Furthermore, we improved an existing semiempirical model in order to reproduce the spectra and study the evolution of the spectral lines.Results. The UV/optical light curve shows a double peak at ∼50 and ∼100 days after the first detection, and it declines and flattens afterward, reaching preoutburst levels after 2000 days of monitoring. The MIR light curve rises almost simultaneously with the optical, but unlike the UV/optical which is approaching the preoutburst levels in the last epochs of our observations, the MIR emission is still rising at the time of writing. The optical spectra show broad Balmer features and the strongest broad Fe II emission ever detected in a nuclear transient. This broad Fe II emission was not present in the archival preoutburst spectrum and almost completely disappeared +1868 days after the outburst. We found that the majority of the flux of the broad Balmer and Fe II lines is produced by photoionization. We detect only weak X-ray emission in the 0.5−8 keV band at the location of PS16dtm, at +848, +1130, and +1429 days past the outburst. This means that the X-ray emission continues to be lower by at least an order of magnitude, compared to archival, preoutburst measurements.Conclusions. We confirm that the observed properties of PS16dtm are difficult to reconcile with normal AGN variability. The TDE scenario continues to be a plausible explanation for the observed properties, even though PS16dtm shows differences compared to TDE in quiescent galaxies. We suggest that this event is part of a growing sample of TDEs that show broad Balmer line profiles and Fe II complexes. We argue that the extreme variability seen in the AGN host due to PS16dtm may have easily been misclassified as a CLAGN, especially if the rising part of the light curve had been missed. This implies that some changing look episodes in AGN may be triggered by TDEs. Imaging and spectroscopic data of AGN with good sampling are needed to enable testing of possible physical mechanisms behind the extreme variability in AGN.
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| 10. |
- Wijns, W, et al.
(författare)
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Myocardial revascularization
- 2011
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Ingår i: REVISTA PORTUGUESA DE CARDIOLOGIA. - : Elsevier BV. - 0870-2551 .- 2174-2049. ; 30:12, s. 951-1005
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
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