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Sökning: WFRF:(Takala Timo)

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1.
  • Kim, Chang, et al. (författare)
  • Training effects of electrically induced dynamic contractions in human quadriceps muscle.
  • 1995
  • Ingår i: Aviation, Space and Environmental Medicine. - 0095-6562 .- 1943-4448. ; 66, s. 251-255
  • Tidskriftsartikel (refereegranskat)abstract
    • The effects of electrically induced dynamic muscle contractions on muscle endurance, strength, morphology and enzymatic adaptation were studied in seven male physical education students. The training program consisted of electrically induced one-leg extensions on a modified Krogh cycle with a 30-Watt (W) load for 60 min, 3 times a week for 4 weeks. Muscle fiber type composition was unchanged, but diffusional capacity was increased after electromyostimulation training. The endurance capacity in the trained leg increased by 82% (p < 0.01), but there were no significant changes in citrate synthase, phosphofructokinase activities, and carbonic anhydrase III and myoglobin contents, suggesting that neural adaptation and learning were more important factors for the increased endurance capacity than enzymatic adaptation. Prolyl 4-hydroxylase activity, a marker of collagen biosynthesis, increased 3-fold (p < 0.01) as a result of the training. This could be due to muscle damage caused by electrically induced muscle contractions. In conclusion, electrically induced dynamic muscle contractions can increase muscle endurance without clear concominant changes in muscle morphologic and enzymatic adaptation. Increased prolyl 4-hydroxylase activity could suggest muscle damage caused by electrically induced muscle contractions.
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2.
  • Kääpä, Eeva, et al. (författare)
  • Elevated protein content and prolyl 4-hydroxylase activity in severely degenerated human annulus fibrosus.
  • 2000
  • Ingår i: Connective Tissue Research. - : Informa Healthcare. - 0300-8207 .- 1607-8438. ; 41:2, s. 93-99
  • Tidskriftsartikel (refereegranskat)abstract
    • Alterations involved with the intervertebral disc degeneration are partly well described, however, it is not so well known how collagen network is affected by the disease. We analyzed the rate of collagen biosynthesis (estimated by the enzymic activities of prolyl 4-hydroxylase and galactosylhydroxylysyl glucosyltransferase) and the level of hydroxylysylpyridinoline and lysylpyridinoline crosslinks both in normal (n=7) and degenerated (n=7) human annulus fibrosus. The activity of prolyl 4-hydroxylase was significantly increased in degenerated tissue. However, no significant changes in the collagen content or in the amount of hydroxylysylpyridinoline and lysylpyridinoline collagen crosslinks were observed. On the other hand, the content of soluble proteins was significantly increased. Our results suggest that collagen biosynthesis is increased in degenerated human annulus fibrosus, obviously to compensate the impairment of collagen fibers. The faster turnover of collagen in degenerated annulus fibrosus, suggested by the increased prolyl 4-hydroxylase activity and unchanged collagen content, seems not to cause any significant changes in its mature pyridinium crosslink concentrations.
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4.
  • Lohmander, Stefan, et al. (författare)
  • Osteoarthritis
  • 2003
  • Ingår i: Textbook of sports medicine. - 0632065095 ; , s. 422-422:10, s. 1402-1430, s. 1301-1301
  • Bokkapitel (övrigt vetenskapligt/konstnärligt)
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5.
  • Pulliainen, Jouni, et al. (författare)
  • Early snowmelt significantly enhances boreal springtime carbon uptake
  • 2017
  • Ingår i: Proceedings of the National Academy of Sciences of the United States of America. - : Proceedings of the National Academy of Sciences. - 0027-8424. ; 114:42, s. 11081-11086
  • Tidskriftsartikel (refereegranskat)abstract
    • We determine the annual timing of spring recovery from spaceborne microwave radiometer observations across northern hemisphere boreal evergreen forests for 1979–2014. We find a trend of advanced spring recovery of carbon uptake for this period, with a total average shift of 8.1 d (2.3 d/decade). We use this trend to estimate the corresponding changes in gross primary production (GPP) by applying in situ carbon flux observations. Micrometeoro-logical CO2 measurements at four sites in northern Europe and North America indicate that such an advance in spring recovery would have increased the January–June GPP sum by 29 g·C·m−2 [8.4 g·C·m−2 (3.7%)/decade]. We find this sensitivity of the measured springtime GPP to the spring recovery to be in accordance with the corresponding sensitivity derived from simulations with a land ecosystem model coupled to a global circulation model. The model-predicted increase in springtime cumulative GPP was 0.035 Pg/decade [15.5 g·C·m−2 (6.8%)/decade] for Eurasian forests and 0.017 Pg/decade for forests in North America [9.8 g·C·m−2 (4.4%)/decade]. This change in the springtime sum of GPP related to the timing of spring snowmelt is quantified here for boreal evergreen forests.
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