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Melting mapping in nanochannels

Reisner, Walter W. (author)
Lund University
Flyvbjerg, Henrik (author)
Technical University of Denmark
Tegenfeldt, Jonas O. (author)
Lund University,Lunds universitet,Fasta tillståndets fysik,Fysiska institutionen,Institutioner vid LTH,Lunds Tekniska Högskola,Solid State Physics,Department of Physics,Departments at LTH,Faculty of Engineering, LTH
 (creator_code:org_t)
2008
2008
English 3 s.
In: ; , s. 1516-1518
  • Conference paper (peer-reviewed)
Abstract Subject headings
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  • We demonstrate direct visualization of melting mapping of DNA stretched in nanoscale channels[1] using standard staining methods and epifluorescence microscopy to gain information on the local AT/GC ratio along large DNA molecules. Our development opens up a novel route to mapping of large-scale genomic variations.

Keyword

DNA
Genomics
Melting
Nanofluidics

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