Sökning: WFRF:(Thornell L E)
> Fridén Jan 1953 >
Spastic wrist flexo...
Spastic wrist flexors are more severely affected than wrist extensors in children with cerebral palsy
-
- Ponten, E. (författare)
- Karolinska Institutet,Umeå universitet,Institutionen för integrativ medicinsk biologi (IMB),Department of Paediatric Orthopaedics, Astrid Lindgren Children’s Hospital, Karolinska University Hospital, Stockholm
-
- Fridén, Jan, 1953 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för de kirurgiska disciplinerna, Avdelningen för ortopedi,Institute of Surgical Sciences, Department of Orthopaedics
-
- Thornell, Lars-Eric (författare)
- Umeå universitet,Institutionen för integrativ medicinsk biologi (IMB)
-
visa fler...
-
Lieber, R. L. (författare)
-
visa färre...
-
(creator_code:org_t)
- John Wiley & Sons, 2005
- 2005
- Engelska.
-
Ingår i: Dev Med Child Neurol. - : John Wiley & Sons. - 0012-1622 .- 1469-8749. ; 47:6, s. 384-9
- Relaterad länk:
-
https://onlinelibrar...
-
visa fler...
-
https://gup.ub.gu.se...
-
https://urn.kb.se/re...
-
https://doi.org/10.1...
-
http://kipublication...
-
visa färre...
Abstract
Ämnesord
Stäng
- Morphological properties of skeletal muscle were compared between wrist flexors and extensors within the same children (n = 8, six females, two males; age range 4 to 9y, median age 7 y) with wrist muscle imbalance secondary to spastic cerebral palsy (CP). Five patients had hemiplegic CP, two diplegic CP, and one patient had tetraplegic CP. Muscle biopsies were taken during either tendon transfer or tendon lengthening procedures. Analyses included distribution of muscle fibre types, fibre sizes, and expression of developmental myosins. Extensor fibre area was significantly greater than flexor fibre area for type 2A fibres and type 2B fibres but not for type 1 fibres. Coefficient of variation (CV) of fibre size for all three fibre types was greater for flexors compared with extensors. The greatest CV was observed for the type 2A fibres in flexors (39.5 [3.6%]). A wide variation was observed for expression of developmental myosin with the magnitude of the expression being greater, but not statistically significant, in flexors compared with extensors (5.4/mm2 vs 0.53/mm2). These data demonstrate that significant secondary myopathy of wrist flexor muscles results from CP.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kirurgi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Surgery (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Pediatrik (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Pediatrics (hsv//eng)
Nyckelord
- Age Factors
- Analysis of Variance
- Biopsy/methods
- Cerebral Palsy/*pathology/*physiopathology
- Child
- Child
- Preschool
- Female
- Humans
- Male
- Muscle Fibers/pathology
- Muscle Spasticity/classification/*pathology/*physiopathology
- Muscle
- Skeletal/metabolism/*pathology/physiopathology
- Myosins/metabolism
- Regression Analysis
- Wrist/*physiopathology
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas