| 1. |
-
- 2019
-
Tidskriftsartikel (refereegranskat)
|
|
| 2. |
|
|
| 3. |
- de la Torre-Robles, Amelia, et al.
(författare)
-
Estimation of the intake of phenol compounds from virgin olive oil of a population from southern Spain
- 2014
-
Ingår i: Food Additives & Contaminants. - Oxon, United Kingdom : Taylor & Francis Group. - 1944-0049 .- 1944-0057. ; 31:9, s. 1460-1469
-
Tidskriftsartikel (refereegranskat)abstract
- The objective of the study was to determine the mean polyphenol composition of different varieties of virgin olive oil (VOO) habitually consumed in the region of southern Spain and to estimate the dietary exposure to olive oil polyphenols in that population. There were statistically significant differences in total polyphenols among varieties, with the Picual variety containing the largest amount with a mean value of 591.8 mg kg(-1). The main phenolic compounds found in the VOOs under study were tyrosol and hydroxytyrosol. The highest amounts of both substances were found in Picual olive oils with concentrations of 2.3-6.6 mg kg(-1). The total intake of polyphenols from VOO ranged between 8.2 mg day(-1) (SD = 4.14) for the under 19 year olds and 21.3 mg day(-1) (SD = 3) for the over 50 year olds. Some polyphenols, including tyrosol and hydroxytyrosol, were consumed principally as olive oil. The intake of these compounds in the studied population was in the range of 88.5-237.4 μg day(-1). This has particular importance as recent studies have demonstrated that hydroxytyrosol helps to improve plasma lipids levels and repair oxidative damage related to cardiovascular disease. There was a greater dietary consumption of polyphenols in olive oil among the participants who more closely followed the Mediterranean diet pattern. A higher consumption of olive oil and therefore a greater exposure to polyphenols was observed in females versus males and in participants of normal weight versus those who were overweight. The total intake of polyphenols from VOO significantly increased with higher age, reflecting the greater intake of this oil by older people, who also show a closer adherence to the Mediterranean diet. The over 50-year-old age group showed the greatest consumption of this olive oil and therefore of phenolic compounds, which are healthy protectors in the human diet that contribute to the acknowledged benefits of the Mediterranean diet.
|
|
| 4. |
- Hamdan, May, et al.
(författare)
-
Development and validation of a nutritional questionnaire for the Palestine population
- 2014
-
Ingår i: Public Health Nutrition. - 1368-9800 .- 1475-2727. ; 17:11, s. 2512-2518
-
Tidskriftsartikel (refereegranskat)abstract
- Objective: Dietary habits vary widely among regions and cultural groups, and FFQ need to be designed for specific populations. The objectives of the present study were to develop and test the repeatability and relative validity of a medium-length semi-quantitative FFQ for measuring the energy and macronutrient intakes of a specific population and to contribute a methodological framework for this procedure.Setting: Palestinian families in the Hebron area.Design: After a preliminary survey of a subgroup of homemakers using 3 d diet recall, stepwise multiple regression analysis was used for selected nutrients to choose foods for inclusion in the FFQ.Subjects: The FFQ was administered to a study population of 169 women representing the same number of families.Results: The Wilcoxon test and Bland-Altman plots were used to compare the FFQ results with the mean 3 d diet recall results. A high level of concordance was found, validating the FFQ. In this population, the mean consumption of SFA was above recommendations and the intakes of vitamin D, folic acid, Ca, Fe and K were deficient.Conclusions: The availability of diet assessment instruments designed for specific populations and cultures is of immense value to researchers and policy makers. The study describes a simple and effective method to develop and validate an FFQ for a given population of interest.
|
|
| 5. |
- López, Miguel, et al.
(författare)
-
Hypothalamic AMPK and fatty acid metabolism mediate thyroid regulation of energy balance
- 2010
-
Ingår i: Nature Medicine. - : Nature Publishing Group. - 1078-8956 .- 1546-170X. ; 16:9, s. 1001-1008
-
Tidskriftsartikel (refereegranskat)abstract
- Thyroid hormones have widespread cellular effects; however it is unclear whether their effects on the central nervous system (CNS) contribute to global energy balance. Here we demonstrate that either whole-body hyperthyroidism or central administration of triiodothyronine (T3) decreases the activity of hypothalamic AMP-activated protein kinase (AMPK), increases sympathetic nervous system (SNS) activity and upregulates thermogenic markers in brown adipose tissue (BAT). Inhibition of the lipogenic pathway in the ventromedial nucleus of the hypothalamus (VMH) prevents CNS-mediated activation of BAT by thyroid hormone and reverses the weight loss associated with hyperthyroidism. Similarly, inhibition of thyroid hormone receptors in the VMH reverses the weight loss associated with hyperthyroidism. This regulatory mechanism depends on AMPK inactivation, as genetic inhibition of this enzyme in the VMH of euthyroid rats induces feeding-independent weight loss and increases expression of thermogenic markers in BAT. These effects are reversed by pharmacological blockade of the SNS. Thus, thyroid hormone-induced modulation of AMPK activity and lipid metabolism in the hypothalamus is a major regulator of whole-body energy homeostasis.
|
|
| 6. |
- Monteagudo, Celia, 1984-, et al.
(författare)
-
Proposal of a mediterranean diet serving score
- 2015
-
Ingår i: PLOS ONE. - : Public Library Science. - 1932-6203. ; 10:6
-
Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND AND AIMS: Numerous studies have demonstrated a relationship between Mediterranean Diet (MD) adherence and the prevention of cardiovascular diseases, cancer, and diabetes, etc. The study aim was to validate a novel instrument to measure MD adherence based on the consumption of food servings and food groups, and apply it in a female population from southern Spain and determining influential factors.METHODS AND RESULTS: The study included 1,155 women aged 12-83 yrs, classified as adolescents, adults, and over-60-yr-olds. All completed a validated semi-quantitative food frequency questionnaire (FFQ). The Mediterranean Dietary Serving Score (MDSS) is based on the latest update of the Mediterranean Diet Pyramid, using the recommended consumption frequency of foods and food groups; the MDSS ranges from 0 to 24. The discriminative power or correct subject classification capacity of the MDSS was analyzed with the Receiver Operating Characteristic (ROC) curve, using the MDS as reference method. Predictive factors for higher MDSS adherence were determined with a logistic regression model, adjusting for age. According to ROC curve analysis, MDSS evidenced a significant discriminative capacity between adherents and non-adherents to the MD pattern (optimal cutoff point=13.50; sensitivity=74%; specificity=48%). The mean MDSS was 12.45 (2.69) and was significantly higher with older age (p<0.001). Logistic regression analysis showed highest MD adherence by over 60-year-olds with low BMI and no habit of eating between meals.CONCLUSIONS: The MDSS is an updated, easy, valid, and accurate instrument to assess MD adherence based on the consumption of foods and food groups per meal, day, and week. It may be useful in future nutritional education programs to prevent the early onset of chronic non-transmittable diseases in younger populations.
|
|
| 7. |
- Rivas, Ana, et al.
(författare)
-
Association of bisphenol A exposure with dietary quality indices in Spanish schoolchildren
- 2016
-
Ingår i: Food and Chemical Toxicology. - Oxford, United, Kingdom : Elsevier. - 0278-6915 .- 1873-6351. ; 94, s. 25-30
-
Tidskriftsartikel (refereegranskat)abstract
- Young children, whose growth and development are highly dependent on the endocrine system, are particularly vulnerable to endocrine disruptor exposure. The main objectives of this study were to measure BPA migration levels from cans, fruit juice bottles/packs, and microwave containers used for food/drinks consumed by a sample of 6- to 8-year old schoolchildren in Spain and to estimate the relationship between their resulting BPA exposure and diet quality index scores (Mediterranean Diet Score and Breakfast Quality Index). The mean BPA concentration was 11.8 ng/mL for vegetable cans, 22.1 ng/mL for pulse cans, 3.6 ng/mL for juice bottles/packs, and 1.2 ng/mL for microwave containers. Results revealed a significant association between the Mediterranean Diet Score and low BPA exposure of the children. BPA exposure below the median level was significantly associated with a higher score in both the first-grade (P = 0.030) and second-grade (p = 0.0001) groups. However, no association was found between BPA exposure and the Breakfast Quality Index. In conclusion, children with a stronger adherence to a Mediterranean-like diet appear to be less exposed to BPA migrating from food packaging and microwave containers. Further research is warranted on the inadvertent exposure of children to endocrinedisrupting chemicals from these sources.
|
|
| 8. |
- Thomas, HS, et al.
(författare)
-
- 2019
-
swepub:Mat__t
|
|
