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Chronic inflammatio...
Chronic inflammation in the etiology of disease across the life span
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- Furman, David (author)
- Stanford University,Buck Institute for Research on Aging,Austral University, Argentina
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- Campisi, Judith (author)
- Buck Institute for Research on Aging,Lawrence Berkeley National Laboratory
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- Verdin, Eric (author)
- Buck Institute for Research on Aging
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- Carrera-Bastos, Pedro (author)
- Lund University,Lunds universitet,Allmänmedicin och klinisk epidemiologi,Forskargrupper vid Lunds universitet,Family Medicine and Clinical Epidemiology,Lund University Research Groups,Center for Primary Health Care Research,Skåne University Hospital
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- Targ, Sasha (author)
- University of California, San Francisco
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- Franceschi, Claudio (author)
- N. I. Lobachevsky State University of Nizhny Novgorod,IRCCS Network Of Neuroscience And Neurorehabilitation, Bologna
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- Ferrucci, Luigi (author)
- National Institute on Aging, United States
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- Gilroy, Derek W. (author)
- University College London
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- Fasano, Alessio (author)
- Harvard Medical School
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- Miller, Gary W. (author)
- Columbia University
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- Miller, Andrew H. (author)
- Emory University
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- Mantovani, Alberto (author)
- Humanitas University,Humanitas Research Hospital,Queen Mary University
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- Weyand, Cornelia M. (author)
- Stanford University
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- Barzilai, Nir (author)
- Yeshiva University
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- Goronzy, Jorg J. (author)
- Stanford University
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- Rando, Thomas A. (author)
- Stanford University,VA Palo Alto Health Care System
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- Effros, Rita B. (author)
- University of California, Los Angeles
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- Lucia, Alejandro (author)
- European University of Madrid,12 de Octubre University Hospital
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- Kleinstreuer, Nicole (author)
- National Institute of Environmental Health Sciences
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- Slavich, George M. (author)
- University of California, Los Angeles
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(creator_code:org_t)
- 2019-12-05
- 2019
- English.
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In: Nature Medicine. - : Springer Science and Business Media LLC. - 1078-8956 .- 1546-170X. ; 25:12, s. 1822-1832
- Related links:
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http://dx.doi.org/10...
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https://www.nature.c...
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https://doi.org/10.1...
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Abstract
Subject headings
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- Although intermittent increases in inflammation are critical for survival during physical injury and infection, recent research has revealed that certain social, environmental and lifestyle factors can promote systemic chronic inflammation (SCI) that can, in turn, lead to several diseases that collectively represent the leading causes of disability and mortality worldwide, such as cardiovascular disease, cancer, diabetes mellitus, chronic kidney disease, non-alcoholic fatty liver disease and autoimmune and neurodegenerative disorders. In the present Perspective we describe the multi-level mechanisms underlying SCI and several risk factors that promote this health-damaging phenotype, including infections, physical inactivity, poor diet, environmental and industrial toxicants and psychological stress. Furthermore, we suggest potential strategies for advancing the early diagnosis, prevention and treatment of SCI.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
Publication and Content Type
- art (subject category)
- ref (subject category)
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To the university's database
- By the author/editor
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Furman, David
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Campisi, Judith
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Verdin, Eric
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Carrera-Bastos, ...
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Targ, Sasha
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Franceschi, Clau ...
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show more...
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Ferrucci, Luigi
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Gilroy, Derek W.
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Fasano, Alessio
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Miller, Gary W.
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Miller, Andrew H ...
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Mantovani, Alber ...
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Weyand, Cornelia ...
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Barzilai, Nir
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Goronzy, Jorg J.
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Rando, Thomas A.
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Effros, Rita B.
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Lucia, Alejandro
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Kleinstreuer, Ni ...
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Slavich, George ...
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Health Sciences
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and Public Health Gl ...
- Articles in the publication
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Nature Medicine
- By the university
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Lund University