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- Backman, PB, et al.
(författare)
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Epidemiology of firearm injuries in a Scandinavian trauma center
- 2020
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Ingår i: European journal of trauma and emergency surgery : official publication of the European Trauma Society. - : Springer Science and Business Media LLC. - 1863-9941. ; 46:3, s. 641-647
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Tidskriftsartikel (refereegranskat)
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- Daryapeyma, A, et al.
(författare)
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Perioperative cytokine response to infection associated with elective arterial surgery
- 2014
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Ingår i: Vascular and endovascular surgery. - : SAGE Publications. - 1938-9116 .- 1538-5744. ; 48:2, s. 116-122
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Tidskriftsartikel (refereegranskat)abstract
- The aim was to assess the cytokine response to acute inflammation and infection in vascular surgery.Design of Study:Single-center, prospective cohort study.Methods:Blood samples from 96 consecutive patients undergoing elective vascular surgery were analyzed for C-reactive protein (CRP), total leukocyte counts (LPK), neutrophil CD64 expression, and cytokines using enzyme-linked immunosorbent assay.Results:Of the 25 investigated cytokines, 22 had lower postoperative mean values compared to preoperative values. Interleukin (IL) 6 (IL-6) was the only cytokine that increased significantly postoperatively. Combined analysis of CRP and CD64 together with IL-6 or IL-10 showed an individually unique association with postoperative infection ( P < .05).Conclusion:We have shown a positive correlation with perioperative infection for the proinflammatory cytokines and the anti-inflammatory cytokine IL-10 as well as a number of chemokines. To our knowledge, this is the first report linking IL-10 and chemokine plasma levels to perioperative infection in vascular surgery.
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