| 1. |
- Culverhouse, R. C., et al.
(författare)
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Collaborative meta-analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to the development of depression
- 2018
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Ingår i: Molecular Psychiatry. - : Springer Science and Business Media LLC. - 1359-4184 .- 1476-5578. ; 23:1, s. 133-142
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Tidskriftsartikel (refereegranskat)abstract
- The hypothesis that the S allele of the 5-HTTLPR serotonin transporter promoter region is associated with increased risk of depression, but only in individuals exposed to stressful situations, has generated much interest, research and controversy since first proposed in 2003. Multiple meta-analyses combining results from heterogeneous analyses have not settled the issue. To determine the magnitude of the interaction and the conditions under which it might be observed, we performed new analyses on 31 data sets containing 38 802 European ancestry subjects genotyped for 5-HTTLPR and assessed for depression and childhood maltreatment or other stressful life events, and meta-analysed the results. Analyses targeted two stressors (narrow, broad) and two depression outcomes (current, lifetime). All groups that published on this topic prior to the initiation of our study and met the assessment and sample size criteria were invited to participate. Additional groups, identified by consortium members or self-identified in response to our protocol (published prior to the start of analysis) with qualifying unpublished data, were also invited to participate. A uniform data analysis script implementing the protocol was executed by each of the consortium members. Our findings do not support the interaction hypothesis. We found no subgroups or variable definitions for which an interaction between stress and 5-HTTLPR genotype was statistically significant. In contrast, our findings for the main effects of life stressors (strong risk factor) and 5-HTTLPR genotype (no impact on risk) are strikingly consistent across our contributing studies, the original study reporting the interaction and subsequent meta-analyses. Our conclusion is that if an interaction exists in which the S allele of 5-HTTLPR increases risk of depression only in stressed individuals, then it is not broadly generalisable, but must be of modest effect size and only observable in limited situations.
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| 2. |
- Wang, R., et al.
(författare)
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Multi-resource dynamic coordinated planning of flexible distribution network
- 2024
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Ingår i: Nature Communications. - : Nature Portfolio. - 2041-1723. ; 15:1
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Tidskriftsartikel (refereegranskat)abstract
- The flexible distribution network presents a promising architecture to accommodate highly integrated distributed generators and increasing loads in an efficient and cost-effective way. The distribution network is characterised by flexible interconnections and expansions based on soft open points, which enables it to dispatch power flow over the entire system with enhanced controllability and compatibility. Herein, we propose a multi-resource dynamic coordinated planning method of flexible distribution network that allows allocation strategies to be determined over a long-term planning period. Additionally, we establish a probabilistic framework to address source-load uncertainties, which mitigates the security risks of voltage violations and line overloads. A practical distribution network is adopted for flexible upgrading based on soft open points, and its cost benefits are evaluated and compared with that of traditional planning approaches. By adjusting the acceptable violation probability in chance constraints, a trade-off between investment efficiency and operational security can be realised.
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| 3. |
- Christensen, L W, et al.
(författare)
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One-sided Gorenstein rings
- 2024
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Ingår i: Forum mathematicum. - 0933-7741 .- 1435-5337.
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Tidskriftsartikel (refereegranskat)abstract
- Distinctive characteristics of Iwanaga-Gorenstein rings are typically understood through their intrinsic symmetry. We show that several of those that pertain to the Gorenstein global dimensions carry over to the one-sided situation, even without the noetherian hypothesis. Our results yield new relations among homological invariants related to the Gorenstein property, not only Gorenstein global dimensions but also the suprema of projective/injective dimensions of injective/projective modules and finitistic dimensions.
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| 4. |
- Larsson, L. E., et al.
(författare)
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Association of Sarcopenia and Its Defining Components with the Degree of Cognitive Impairment in a Memory Clinic Population
- 2023
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Ingår i: Journal of Alzheimer's Disease. - : IOS Press BV. - 1387-2877 .- 1875-8908. ; 96:2, s. 777-788
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Tidskriftsartikel (refereegranskat)abstract
- Background: Sarcopenia and cognitive impairment are two leading causes of disabilities. Objective: The objective was to examine the prevalence of sarcopenia and investigate the association between sarcopenia diagnostic components (muscle strength, muscle mass, and physical performance) and cognitive impairment in memory clinic patients. Methods: 368 patients were included (age 59.0±7.25 years, women: 58.7%), displaying three clinical phenotypes of cognitive impairments, i.e., subjective cognitive impairment (SCI, 57%), mild cognitive impairment (MCI, 26%), and Alzheimer's disease (AD, 17%). Sarcopenia was defined according to diagnostic algorithm recommended by the European Working Group on Sarcopenia in Older People. Components of sarcopenia were grip strength, bioelectrical impedance analysis, and gait speed. They were further aggregated into a score (0-3 points) by counting the numbers of limited components. Multi-nominal logistic regression was applied. Results: Probable sarcopenia (i.e., reduced grip strength) was observed in 9.6% of the patients, and 3.5% were diagnosed with sarcopenia. Patients with faster gait speed showed less likelihood of MCI (odds ratio [OR]: 0.24, 95% confidence interval [CI]: 0.06-0.90) and AD (OR: 0.12, 95% CI: 0.03-0.60). One or more limited sarcopenia components was associated with worse cognitive function. After adjusting for potential confounders, the association remained significant only for AD (OR 4.29, 95% CI 1.45-11.92). Conclusion: The results indicate a connection between the sarcopenia components and cognitive impairments. Limitations in the sarcopenia measures, especially slow walking speed, were related to poorer cognitive outcomes. More investigationsare required to further verify the causal relationship between sarcopenia and cognitive outcomes.
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| 5. |
- Liu, Z., et al.
(författare)
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Solar harvest : Enhancing carbon sequestration and energy efficiency in solar greenhouses with PVT and GSHP systems
- 2023
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Ingår i: Renewable energy. - : Elsevier Ltd. - 0960-1481 .- 1879-0682. ; 211, s. 112-125
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Tidskriftsartikel (refereegranskat)abstract
- It is universally acknowledged that climate change brings widespread attention to solar greenhouse plant carbon sequestration. Suitable technologies in solar greenhouses were, are, and will be play a leading role in this vital transition. The primary aim of this research is to examine the energy efficiency and carbon sequestration potential of a solar-assisted ground-source heat pump (SAGSHP) heating system. This hybrid system, which integrates a horizontal ground-source heat pump (GSHP) system with PVT and heat storage, can efficiently fulfill the heating demands of a greenhouse and function as a positive energy building. Four plants include cucumber, tomato, cowpea, and lettuce were selected to compare the carbon absorption effects. Results show that the hybrid system outperforms conventional systems, with a coefficient of performance (COP) of 6.71 during peak hours and PVT efficiency over 57.88%, which effectively meet the heat load of the greenhouse and keep the indoor heat comfortable. In addition, for the carbon sequestration potential of four plants, tomato exhibited the highest photosynthetic carbon sequestration of 3522 kgCO2·m−2. Cowpea showed the strongest daily carbon sequestration capacity at 26.86 gCO2m−2d−1 and better economic income. Through the application of this enhanced solar greenhouse, people can enhance the utilization of solar energy, establish flexible interaction between energy and information flow, and make a promising option for sustainable building design.
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| 6. |
- Lyu, Yuexia, et al.
(författare)
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Techno-economic evaluation of an optical fiber based hybrid solar lighting system
- 2020
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Ingår i: Energy Conversion and Management. - : Elsevier Ltd. - 0196-8904 .- 1879-2227. ; 225
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Tidskriftsartikel (refereegranskat)abstract
- Optical fiber solar lighting systems are an appealing approach for illumination applications with the aim of reducing energy consumption and greenhouse gas emissions from artificial lighting. This study presented the design, construction and assessment of an optical fiber based hybrid solar lighting system for illumination of interior spaces. The proposed system combines the features of optical fiber daylighting technology and photovoltaic power generation technology. Specifically, a secondary light concentrator was designed to improve the uniformity of flux distribution and solve the overheating problem of PMMA fibers. The technical feasibility of the hybrid solar lighting system was validated using the fabricated prototype in a 5 m2 darkroom during a whole day test. Experimental results showed that, an average illuminance of 105 lx at a distance of 2 m from the end of optical fiber bundle was achieved, saving 316.82 kWh and reducing 251.24 kg carbon dioxide emissions every year in the studied case. Finally, cost analysis of the proposed hybrid solar lighting system was carried out and compared with three conventional lighting systems. The total payback period of the hybrid solar lighting system was 3.7 years and further reduced to 1.7 years in mass production. In the studied case, the hybrid solar lighting system was economically competitive after 2 years and 12 years of operation in comparison with a 100 W incandescent bulb lighting system and a 30 W T8 fluorescent lamp lighting system, respectively.
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| 7. |
- Wang, F., et al.
(författare)
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Optimal design and operation of hybrid renewable energy system for drinking water treatment
- 2021
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Ingår i: Energy. - : Elsevier Ltd. - 0360-5442 .- 1873-6785. ; 219
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Tidskriftsartikel (refereegranskat)abstract
- The industrial process of drinking water treatment requires intensive energy, leading to high enterprise costs and abundant carbon emissions. To ensure cost-effective and low polluting power supply for the above process, this paper proposes to deploy the grid-connected hybrid renewable system. A multi-objective nonlinear dynamic model mixed with integer variables is established for the decision makers, in which both system configurations and operations as well as benefits trade-offs from four dimensions are simultaneously considered. The ε-constraint method and system planner attitude parameters are introduced to transform the proposed model into its equivalent single objective form, which is further been solved by the LINGO software. A case study in China is given to assess the viability of the proposed model, in which optimal system configuration, economically feasible self-sufficiency ratio and optimal energy balance are obtained. Influences of electricity pricing strategies and natural resource changes on the systems are also analyzed and compared. It is found that the deployment of grid-connected hybrid wind/PV/storage system can help power users to cope with the future electricity price variation risks, with the feasible self-sufficiency ratio reaching 95%.
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| 8. |
- Wang, L., et al.
(författare)
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Design on CO2 capture based on adsorption-absorption integration and energy storage for energy supply buildings with fixed carbon emission
- 2024
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Ingår i: International Journal of Green Energy. - : Taylor and Francis Ltd.. - 1543-5075 .- 1543-5083.
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Tidskriftsartikel (refereegranskat)abstract
- A novel design for the energy storage by adsorption-absorption for the partial CO2 capture of the energy supply buildings with fixed CO2 emission is proposed. The new design successfully utilizes the attainment of the low energy consumption and implements energy storage through adsorption part, overcoming the deficiencies of poor selectivity through absorption part. Numerical approaches have been developed for modeling the adsorption-absorption procedure, while attaining satisfactory agreement with experimental data. The adsorption process is modeled based on the finite volume method, and the absorption process is simulated based on the double-film theory and the rate-based model. The issue of operating parameters upon system assessments has received considerable critical attention by numerical implementations. The results show that the mass fraction of CO2 in the flue gas has been increased to 39.0%. The comprehensive enhancement effects are instrumental at a height of 20 m in the absorption tower. As the CO2 concentration of the flue gas increases from 5.0% to 20.0%, the absorbent flow, absorber diameter, and reboiler specific load decrease by 13.0%, 42.1%, and 16.6%, in respective. The present analysis and design will provide guidance and gain fresh prominence with advantages in the CO2 capture and purification.
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| 9. |
- Ding, J., et al.
(författare)
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Theoretical prediction of the local structures and transport properties of binary alkali chloride salts for concentrating solar power
- 2017
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Ingår i: Nano Energy. - : Elsevier. - 2211-2855 .- 2211-3282. ; 39, s. 380-389
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Tidskriftsartikel (refereegranskat)abstract
- Comprehensive molecular simulations have been carried out to compute local structures and transport properties of different components of binary NaCl-KCl over a wide operating temperature range. The partial radial distribution functions, coordination number curves and angular distribution functions were calculated to analyze the influence of temperature and component on local structures of molten Alkali Chlorides. Transport properties were calculated by using reverse non-equilibrium molecular dynamics (RNEMD) simulations including densities, shear viscosity and thermal conductivity. The results show that ion clusters are considered to be formed and the distance of ion clusters become larger with increasing temperature which has great influence on macro-properties. The calculated properties have a good agreement with the experimental data, and similar method could be used to computationally calculate the properties of various molten salts and their mixtures.
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| 10. |
- Fatima, R., et al.
(författare)
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Sharing information online rationally : An observation of user privacy concerns and awareness using serious game
- 2019
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Ingår i: Journal of Information Security and Applications. - : Elsevier Ltd. - 2214-2134 .- 2214-2126. ; 48
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Tidskriftsartikel (refereegranskat)abstract
- Recent studies have shown that excessive online information disclosure is a major reason of privacy breach. It makes it easy for social engineers to gather information about their targets. The objective of this study is to gather user privacy concerns reported in the literature and categorize them into themes, then design a serious game covering the categorized privacy concerns and evaluate the educational effect of the game regarding dangers associated with excessive online information disclosure. We have conducted a literature review and extracted user privacy concerns reported in 109+ publications. Then we designed a serious game and empirically evaluated the game players awareness of dangers associated with excessive online information disclosure. We find that privacy awareness has a positive long-term impact on users online behavior in terms of controlled information sharing. However, social networking needs drive users to share information online, even knowing the potential risks. The proposed serious game shows positive effect in improving the privacy awareness of participants.
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