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1.	Jakobsson, J., et al. (author) Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 2021 In: Autophagy. - : Informa UK Limited. - 1554-8635 .- 1554-8627. ; 17:1, s. 1-382 Journal article (peer-reviewed)
2.	Ahmad, T, et al. (author) Global patient outcomes after elective surgery: prospective cohort study in 27 low-, middle- and high-income countries 2016 In: British journal of anaesthesia. - : Elsevier BV. - 1471-6771 .- 0007-0912. ; 117:5, s. 601- Journal article (peer-reviewed)
3.	Ahmad, T, et al. (author) In-hospital clinical outcomes after upper gastrointestinal surgery: Data from an international observational study 2017 In: European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology. - : Elsevier BV. - 1532-2157 .- 0748-7983. ; 43:12, s. 2324-2332 Journal article (peer-reviewed)
4.	Ahmad, T, et al. (author) Use of failure-to-rescue to identify international variation in postoperative care in low-, middle- and high-income countries: a 7-day cohort study of elective surgery 2017 In: British journal of anaesthesia. - : Elsevier BV. - 1471-6771 .- 0007-0912. ; 119:2, s. 258-266 Journal article (peer-reviewed)
5.	Aad, G, et al. (author) 2015 swepub:Mat__t
6.	Cortes-Ciriano, I, et al. (author) Author Correction: Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing 2023 In: Nature genetics. - : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 55:6, s. 1076- Journal article (other academic/artistic)
7.	Ridker, PM, et al. (author) Cardiovascular Efficacy and Safety of Bococizumab in High-Risk Patients 2017 In: The New England journal of medicine. - 1533-4406 .- 0028-4793. ; 376:16, s. 1527-1539 Journal article (peer-reviewed)
8.	Chen, A, et al. (author) Single-cell spatial transcriptome reveals cell-type organization in the macaque cortex 2023 In: Cell. - : Elsevier BV. - 1097-4172 .- 0092-8674. ; 186:17, s. 3726- Journal article (peer-reviewed)
9.	Abbafati, C, et al. (author) Five insights from the Global Burden of Disease Study 2019 2020 In: Lancet (London, England). - 1474-547X .- 0140-6736. ; 396:10258, s. 1135-1159 Journal article (peer-reviewed)
10.	Campbell, PJ, et al. (author) Pan-cancer analysis of whole genomes 2020 In: Nature. - : Springer Science and Business Media LLC. - 1476-4687 .- 0028-0836. ; 578:7793, s. 82- Journal article (peer-reviewed)abstract Cancer is driven by genetic change, and the advent of massively parallel sequencing has enabled systematic documentation of this variation at the whole-genome scale1–3. Here we report the integrative analysis of 2,658 whole-cancer genomes and their matching normal tissues across 38 tumour types from the Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium of the International Cancer Genome Consortium (ICGC) and The Cancer Genome Atlas (TCGA). We describe the generation of the PCAWG resource, facilitated by international data sharing using compute clouds. On average, cancer genomes contained 4–5 driver mutations when combining coding and non-coding genomic elements; however, in around 5% of cases no drivers were identified, suggesting that cancer driver discovery is not yet complete. Chromothripsis, in which many clustered structural variants arise in a single catastrophic event, is frequently an early event in tumour evolution; in acral melanoma, for example, these events precede most somatic point mutations and affect several cancer-associated genes simultaneously. Cancers with abnormal telomere maintenance often originate from tissues with low replicative activity and show several mechanisms of preventing telomere attrition to critical levels. Common and rare germline variants affect patterns of somatic mutation, including point mutations, structural variants and somatic retrotransposition. A collection of papers from the PCAWG Consortium describes non-coding mutations that drive cancer beyond those in the TERT promoter4; identifies new signatures of mutational processes that cause base substitutions, small insertions and deletions and structural variation5,6; analyses timings and patterns of tumour evolution7; describes the diverse transcriptional consequences of somatic mutation on splicing, expression levels, fusion genes and promoter activity8,9; and evaluates a range of more-specialized features of cancer genomes8,10–18.

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Result 1-10 of 349

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Type of publication: journal article (330); conference paper (10); research review (2)

Type of content: peer-reviewed (316); other academic/artistic (26)

Author/Editor: Easton, DF (72); Brenner, H (70); Teo, SH (67); Wang, Q. (66); Lubinski, J (60); Nevanlinna, H (60); show more...; Southey, MC (58); Chenevix-Trench, G (57); Zheng, W. (56); Giles, GG (56); Hamann, U (56); Benitez, J. (54); Dennis, J (54); Hall, P (54); Fasching, PA (54); Chang-Claude, J (54); Dunning, AM (53); Couch, FJ (53); Andrulis, IL (52); Jakubowska, A (52); Hopper, JL (51); Haiman, CA (51); Pharoah, PDP (51); Beckmann, MW (49); Garcia-Closas, M (49); Shu, XO (48); Dork, T (48); Matsuo, K (47); Czene, K (46); Peterlongo, P (46); Milne, RL (46); Bolla, MK (46); Shen, CY (46); Simard, J (46); Lindblom, A (45); Schmidt, MK (45); Mannermaa, A (45); Lambrechts, D (45); Kang, D. (44); Muir, K (44); Cox, A (43); Radice, P (43); Bojesen, SE (43); Schmutzler, RK (43); Anton-Culver, H (42); Truong, T (42); Le Marchand, L (42); Devilee, P (42); Chanock, SJ (42); Neuhausen, SL (42); show less...

University: Karolinska Institutet (308); Lund University (97); Uppsala University (65); University of Gothenburg (27); Umeå University (25); Högskolan Dalarna (20); show more...; Stockholm University (6); Linköping University (6); University of Skövde (5); Royal Institute of Technology (4); Chalmers University of Technology (3); Örebro University (2); Swedish University of Agricultural Sciences (2); Jönköping University (1); Mid Sweden University (1); Södertörn University (1); show less...

Language: English (349)

Research subject (UKÄ/SCB): Medical and Health Sciences (109); Natural sciences (43); Social Sciences (1)

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