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Träfflista för sökning "WFRF:(Westerlund Fredrik 1978) ;pers:(Tegenfeldt J. O.)"

Sökning: WFRF:(Westerlund Fredrik 1978) > Tegenfeldt J. O.

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1.
  • Alizadehheidari, Mohammadreza, 1987, et al. (författare)
  • Nanoconfined circular DNA
  • 2014
  • Ingår i: 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014. - 9780979806476 ; , s. 1353-1355
  • Konferensbidrag (refereegranskat)abstract
    • Studies of nanoconfined circular DNA are of interest both from a biological as well as a fundamental polymer physics perspective. We here present the use of nanofluidic channels as a tool for comparing statics and dynamics of the linear and circular configuration of the same DNA molecule.
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2.
  • Beech, J. P., et al. (författare)
  • What do photons do to fluorescently stained DNA in confinement?
  • 2013
  • Ingår i: 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013; Freiburg; Germany; 27 October 2013 through 31 October 2013. ; 1, s. 5-7
  • Konferensbidrag (refereegranskat)abstract
    • We have studied a selection of factors influencing the damage of DNA in nanochannels during fluorescence imaging. For cutting and nicking of DNA we show that the DNA is shortened during imaging. To avoid photodamage over the course of several hours of a typical experiment, we demonstrate the importance of an oxygen free gas to propel the buffer solution through the device. Finally, by varying the size of the channels, we show indications that higher DNA concentrations lead to higher rates of photodamage necessitating a balance between needs for highly stretched DNA and needs for long measurement times.
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