SwePub
Tyck till om SwePub Sök här!
Sök i SwePub databas

  Utökad sökning

Träfflista för sökning "WFRF:(Wik E) "

Sökning: WFRF:(Wik E)

  • Resultat 1-10 av 22
Sortera/gruppera träfflistan
   
NumreringReferensOmslagsbildHitta
1.
  •  
2.
  •  
3.
  •  
4.
  •  
5.
  •  
6.
  •  
7.
  •  
8.
  • Husby, O., et al. (författare)
  • Dealing with L1 background and L2 dialects in Norwegian CAPT
  • 2011
  • Ingår i: Proceedings of ISCA International Workshop on Speech and Language Technology in Education. - : The International Society for Computers and Their Applications (ISCA).
  • Konferensbidrag (refereegranskat)abstract
    • This article describes the CALST project, in which the primary aim is to develop Ville-N, a CAPT system for learners of Norwegian as a second language. Since there is no accepted pronunciation standard in Norwegian, the system uses four dialects (represented by one male and one female speaker each). Ville-N makes use of L1-L2map, a tool for multi-lingual contrastive analysis, to generate a list of expected pronunciation problems. These can be used to tailor pronunciation and listening exercises. The tool can also be used for other target languages. We propose L1-L2map as a collaborative tool for the CAPT community. Index Terms. CAPT, Ville-N, Norwegian, dialects, multi-lingual contrastive analysis, L1-L2map
  •  
9.
  • Kruger, K, et al. (författare)
  • Expression of Nestin associates with BRCA1 mutations, a basal-like phenotype and aggressive breast cancer
  • 2017
  • Ingår i: Scientific reports. - : Springer Science and Business Media LLC. - 2045-2322. ; 7:1, s. 1089-
  • Tidskriftsartikel (refereegranskat)abstract
    • We here examined whether Nestin, by protein and mRNA levels, could be a predictor of BRCA1 related breast cancer, a basal-like phenotype, and aggressive tumours. Immunohistochemical staining of Nestin was done in independent breast cancer hospital cohorts (Series I-V, total 1257 cases). Also, TCGA proteomic data (n = 103), mRNA microarray data from TCGA (n = 520), METABRIC (n = 1992), and 6 open access breast cancer datasets (n = 1908) were analysed. Patients with Nestin protein expression in tumour cells more often had BRCA1 germline mutations (OR 8.7, p < 0.0005, Series III), especially among younger patients (<40 years at diagnosis) (OR 16.5, p = 0.003). Nestin protein positivity, observed in 9–28% of our hospital cases (Series I-IV), was independently associated with reduced breast cancer specific survival (HR = 2.0, p = 0.035) and was consistently related to basal-like differentiation (by Cytokeratin 5, OR 8.7–13.8, p < 0.0005; P-cadherin OR 7.0–8.9, p < 0.0005; EGFR staining, OR 3.7–8.2, p ≤ 0.05). Nestin mRNA correlated significantly with Nestin protein expression (ρ = 0.6, p < 0.0005), and high levels were seen in the basal-like intrinsic subtype. Gene expression signalling pathways linked to high Nestin were explored, and revealed associations with stem-like tumour features. In summary, Nestin was strongly associated with germline BRCA1 related breast cancer, a basal-like phenotype, reduced survival, and stemness characteristics.
  •  
10.
  •  
Skapa referenser, mejla, bekava och länka
  • Resultat 1-10 av 22

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy