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1.	Pedersen, TR, et al. (author) Cholesterol lowering and the use of healthcare resources. Results of the Scandinavian Simvastatin Survival Study 1996 In: Circulation. - 0009-7322. ; 93:10, s. 1796-1802 Journal article (peer-reviewed)
2.	Jiang, X., et al. (author) Shared heritability and functional enrichment across six solid cancers 2019 In: Nature Communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 10 Journal article (peer-reviewed)abstract Quantifying the genetic correlation between cancers can provide important insights into the mechanisms driving cancer etiology. Using genome-wide association study summary statistics across six cancer types based on a total of 296,215 cases and 301,319 controls of European ancestry, here we estimate the pair-wise genetic correlations between breast, colorectal, head/neck, lung, ovary and prostate cancer, and between cancers and 38 other diseases. We observed statistically significant genetic correlations between lung and head/neck cancer (r(g) = 0.57, p = 4.6 x 10(-8)), breast and ovarian cancer (r(g) = 0.24, p = 7 x 10(-5)), breast and lung cancer (r(g) = 0.18, p = 1.5 x 10(-6)) and breast and colorectal cancer (r(g) = 0.15, p = 1.1 x 10(-4)). We also found that multiple cancers are genetically correlated with non-cancer traits including smoking, psychiatric diseases and metabolic characteristics. Functional enrichment analysis revealed a significant excess contribution of conserved and regulatory regions to cancer heritability. Our comprehensive analysis of cross-cancer heritability suggests that solid tumors arising across tissues share in part a common germline genetic basis.
3.	Orth, M, et al. (author) Observing Huntington's disease: the European Huntington's Disease Network's REGISTRY 2011 In: Journal of neurology, neurosurgery, and psychiatry. - : BMJ. - 1468-330X .- 0022-3050. ; 82:12, s. 1409- Journal article (other academic/artistic)
4.	Kapelios, CJ, et al. (author) Sacubitril/valsartan eligibility and outcomes in the ESC-EORP-HFA Heart Failure Long-Term Registry: bridging between European Medicines Agency/Food and Drug Administration label, the PARADIGM-HF trial, ESC guidelines, and real world 2019 In: European journal of heart failure. - : Wiley. - 1879-0844 .- 1388-9842. ; 21:11, s. 1383-1397 Journal article (peer-reviewed)
5.	Matejcic, M, et al. (author) Author Correction: Germline variation at 8q24 and prostate cancer risk in men of European ancestry 2019 In: Nature communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 10:1, s. 382- Journal article (peer-reviewed)abstract The original version of this Article contained an error in the spelling of the author Manuela Gago-Dominguez, which was incorrectly given as Manuela G. Dominguez. This has now been corrected in both the PDF and HTML versions of the Article.
6.	Speliotes, Elizabeth K., et al. (author) Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index 2010 In: Nature Genetics. - : Springer Science and Business Media LLC. - 1061-4036 .- 1546-1718. ; 42:11, s. 937-948 Journal article (peer-reviewed)abstract Obesity is globally prevalent and highly heritable, but its underlying genetic factors remain largely elusive. To identify genetic loci for obesity susceptibility, we examined associations between body mass index and ~2.8 million SNPs in up to 123,865 individuals with targeted follow up of 42 SNPs in up to 125,931 additional individuals. We confirmed 14 known obesity susceptibility loci and identified 18 new loci associated with body mass index (P < 5 × 10−8), one of which includes a copy number variant near GPRC5B. Some loci (at MC4R, POMC, SH2B1 and BDNF) map near key hypothalamic regulators of energy balance, and one of these loci is near GIPR, an incretin receptor. Furthermore, genes in other newly associated loci may provide new insights into human body weight regulation.
7.	Jiang, X, et al. (author) Publisher Correction: Shared heritability and functional enrichment across six solid cancers 2019 In: Nature communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 10:1, s. 4386- Journal article (other academic/artistic)abstract An amendment to this paper has been published and can be accessed via a link at the top of the paper.
8.	Mach, F., et al. (author) 2019 ESC/EAS guidelines for the management of dyslipidaemias: Lipid modification to reduce cardiovascular risk 2019 In: Atherosclerosis. - : Elsevier BV. - 0021-9150. ; 290, s. 140-205 Journal article (peer-reviewed)
9.	Wang, Anqi, et al. (author) Characterizing prostate cancer risk through multi-ancestry genome-wide discovery of 187 novel risk variants 2023 In: Nature Genetics. - : Springer Nature. - 1061-4036 .- 1546-1718. ; 55:12, s. 2065-2074 Journal article (peer-reviewed)abstract The transferability and clinical value of genetic risk scores (GRSs) across populations remain limited due to an imbalance in genetic studies across ancestrally diverse populations. Here we conducted a multi-ancestry genome-wide association study of 156,319 prostate cancer cases and 788,443 controls of European, African, Asian and Hispanic men, reflecting a 57% increase in the number of non-European cases over previous prostate cancer genome-wide association studies. We identified 187 novel risk variants for prostate cancer, increasing the total number of risk variants to 451. An externally replicated multi-ancestry GRS was associated with risk that ranged from 1.8 (per standard deviation) in African ancestry men to 2.2 in European ancestry men. The GRS was associated with a greater risk of aggressive versus non-aggressive disease in men of African ancestry (P = 0.03). Our study presents novel prostate cancer susceptibility loci and a GRS with effective risk stratification across ancestry groups.
10.	Conti, DV, et al. (author) Publisher Correction: Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction 2021 In: Nature genetics. - : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 53:3, s. 413-413 Journal article (other academic/artistic)

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Type of publication: journal article (355); conference paper (51); reports (2); book chapter (2); other publication (1); research review (1); show more...; show less...

Type of content: peer-reviewed (343); other academic/artistic (69)

Author/Editor: Wiklund, F (99); Wiklund, P (85); Gronberg, H (75); Kote-Jarai, Z (52); Schleutker, J (49); Haiman, CA (45); show more...; Kibel, AS (43); Travis, RC (43); Muir, K (42); Stanford, JL (42); Maier, C (42); Brenner, H (41); Giles, GG (40); Al Olama, AA (40); Batra, J (40); Cybulski, C (39); Teixeira, MR (38); Kaneva, R (38); Nordestgaard, BG (37); Cannon-Albright, L (37); Eeles, RA (37); Berndt, SI (35); Khaw, KT (34); Pashayan, N (34); Neal, DE (34); Thibodeau, SN (33); Egevad, L (32); Benlloch, S (32); Albanes, D (31); Pandha, H (30); Easton, DF (29); Kraft, P (29); Hamdy, FC (29); Park, JY (29); Hunter, DJ (28); Donovan, JL (28); Wiklund, Fredrik (27); Henderson, BE (27); Aly, M (27); Wiklund, NP (26); Le Marchand, L (25); John, EM (24); Mottrie, A (23); Conti, DV (23); Lindstrom, S (23); Schumacher, FR (23); Hosseini, A. (22); Richstone, L (22); Xu, JF (22); Ingles, SA (22); show less...

University: Karolinska Institutet (276); University of Gothenburg (63); Uppsala University (60); Umeå University (55); Lund University (11); Mälardalen University (10); show more...; Linköping University (9); Royal Institute of Technology (5); Stockholm University (4); Högskolan Dalarna (4); Jönköping University (3); Mid Sweden University (3); Karlstad University (3); Luleå University of Technology (2); Örebro University (2); Linnaeus University (2); RISE (2); Halmstad University (1); University of Skövde (1); University of Borås (1); Blekinge Institute of Technology (1); Marie Cederschiöld högskola (1); Swedish University of Agricultural Sciences (1); show less...

Language: English (406); Swedish (3); Danish (1); Norwegian (1); Undefined language (1)

Research subject (UKÄ/SCB): Medical and Health Sciences (100); Natural sciences (26); Engineering and Technology (12); Social Sciences (5); Agricultural Sciences (1); Humanities (1)

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